Stephen Moses

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Stephen Moses
Associates With:
Gilgal Society
Circlist
Colleagues & Benefactors:
Daniel T. Halperin
Edgar J. Schoen
Robert C. Bailey
Bertran Auvert
Maria J. Wawer
Brian J. Morris
Avahan project
Funded by The World Bank

Stephen Moses, Professor, Departments of Medical Microbiology, Community Health Sciences and Medicine. Stephen Moses has been a circumcision proponent since at least 1994.[1] Moses (along with Robert C. Bailey) was responsible for one of the three major African circumcision trials (funded by NIAID and the Canadian Institutes of Health Research)[2] which are being used by the World Health Organization (under the guide of UNAIDS) to endorse circumcision as an HIV prevention method.[3]

Interests

According to Stephen's bio, his interest is in biological and behavioural risk factors for STI/HIV transmission.[4] Moses has been an advocate of circumcision since at least 1994.[1]

RCT in Kenya

Three trials were funded by the American National Institutes of Health.[5]Of the three RCTs being used by the WHO to endorse circumcision as HIV prevention, Stephen Moses and Robert C. Bailey headed the RCT that was carried out in Kenya.[6] Moses obviously brought his pre-existing bias in favor of male circumcision into the trial, so he did not start from a neutral position.

Moses' research on circumcision protection from HIV infection is now completely discredited. Boyle & Hill (2011) reviewed the three randomized controlled trials (RCTs) and found disabling methodological and statistical errors in all three. Although a 60 percent relative reduction in HIV was claimed, the absolute reduction was a statistically insignificant 1.3 percent.[7] Garenne & Matthews (2019) report that circumcised men have as much HIV infection as intact men.[8]

Active projects

Recent publications

  • Prevalence and risk factors for human papillomavirus infection by penile site in uncircumcised Kenyan men.[9]
    Smith JS, Hudgens MG, Bailey RC, Agot K, Ndinya-Achola JO, Moses S, et al. Int J Cancer 2010; 126: 572-7.
  • Top Achievements in Health Research: Male circumcision: a new approach to reducing HIV transmission.[10]
    Moses S. CIHR/CMAJ 2009; 181: E134-5.
  • Does sex in the early period after circumcision increase HIV-seroconversion risk? Pooled analysis of adult male circumcision clinical trials.[11]
    Mehta SD, Gray RH, Auvert B, Moses S , Kigozi G, Taljaard D, Puren A, Agot K, Serwadda D, Parker CB, Wawer MJ, Bailey RC. AIDS 2009; 23: 1557-64.
  • Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomised controlled trial.[12]
    Bailey RC, Moses S , Parker CB, Agot K, Maclean I, Krieger JN, et al. Lancet 2007; 369: 643-56.
  • Modelling the public health impact of male circumcision for HIV prevention in high prevalence areas in Africa.[13]
    Nagelkerke NJD, Moses S, de Vlas S, Bailey RC. BMC Infect Dis 2007; 7: 16.
  • Adult male circumcision outcomes: experience in a developing country setting.[14]
    Krieger J, Bailey RC, Agot K, Parker C, Ndinya-Achola JO, Moses S, et al. Urol Int 2007; 78: 235-40.

See also

References

  1. ↑ a b REFjournal Moses, S., Bradley, J.E., Ndinya-Achola, J.O., Nagelkerke, N.J., Ronald, A.R.. The association between lack of male circumcision and risk for HIV infection: a review of the epidemiological data. Sex Transm Dis. 1994; 21: 201-210.
  2. ↑ REFjournal Krieger, J.N., Bailey, R.C., Opeya, J., et al. Adult male circumcision: results of a standardized procedure in Kisumu District, Kenya. BJU Int.. November 2005; 96(7): 1109–13. PMID. DOI.
  3. ↑ REFweb World Health Organization (27 March 2007). WHO and UNAIDS announce recommendations from expert consultation on male circumcision for HIV prevention. Retrieved 23 February 2011.
  4. ↑ a b c d e f REFweb Dr. Moses, Stephen. [<title> parameter missing!, University of Manitoba. Retrieved 23 February 2011.
  5. ↑ REFweb (2016). HIV/AIDS, Doctors Opposing Circumcision. Retrieved 23 March 2020.
    Quote: ...funding from the United States National Institutes of Health to conduct randomized controlled trials (RCTs) in Africa.
  6. ↑ Bailey RC, Moses S, Parker CB, et al. Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomised controlled trial. Lancet 2007;369:643-56. Abstract
  7. ↑ REFjournal Boyle, Gregory J., Hill, George. Sub-Saharan African randomised clinical trials into male circumcision and HIV transmission: Methodological, ethical and legal concerns. J Law Med. December 2011; 19(2): 316-334. PMID. Retrieved 23 March 2020.
  8. ↑ REFjournal Garenne, M, Matthews, A. Voluntary medical male circumcision and HIV in Zambia: expectations and observations. J Biosoc Science. 1 October 2019; 14: 1-13. PMID. DOI. Retrieved 25 March 2020.
  9. ↑ REFjournal Smith, J.S., Backes, D.M., Hudgens, M.G., et al. Prevalence and risk factors of human papillomavirus infection by penile site in uncircumcised Kenyan men. Int. J. Cancer. January 2010; 126(2): 572–7. PMID. PMC. DOI.
  10. ↑ REFjournal Moses, S.. Male circumcision: a new approach to reducing HIV transmission. CMAJ. October 2009; 181(8): E134–5. PMID. PMC. DOI.
  11. ↑ REFjournal Mehta, S.D., Gray, R.H., Auvert, B., et al. Does sex in the early period after circumcision increase HIV-seroconversion risk? Pooled analysis of adult male circumcision clinical trials. AIDS. July 2007; 23(12): 1557–64. PMID. PMC. DOI.
  12. ↑ REFjournal Bailey, R.C., Moses, S., Parker, C.B., et al. Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomised controlled trial. Lancet. February 2007; 369(9562): 643–56. PMID. DOI.
  13. ↑ REFjournal Nagelkerke, N.J., Moses, S., de Vlas, S.J., Bailey, R.C.. Modelling the public health impact of male circumcision for HIV prevention in high prevalence areas in Africa. BMC Infect. Dis.. 2007; 7: 16. PMID. PMC. DOI.
  14. ↑ REFjournal Krieger, J.N., Bailey, R.C., Opeya, J.C., et al. Adult male circumcision outcomes: experience in a developing country setting. Urol. Int.. 2007; 78(3): 235–40. PMID. DOI.
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