Microbiome: Difference between revisions
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The '''microbiome''' is the complete genetic content of all the microorganisms that typically inhabit a particular environment, especially a site on or in the body, such as the skin or the gastrointestinal tract.<ref>{{REFweb | The '''microbiome''' is the complete genetic content of all the microorganisms that typically inhabit a particular environment, especially a site on or in the body, such as the skin or the gastrointestinal tract.<ref>{{REFweb | ||
|url=https://medical-dictionary.thefreedictionary.com/Microbiome | |url=https://medical-dictionary.thefreedictionary.com/Microbiome | ||
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}}</ref> | }}</ref> | ||
Segre (2023) | The Human Microbiome Project Consortium (2012) reported a remarkable diversity in the healthy human microbiome.<ref>{{REFjournal | ||
|last=Human Microbiome Project Consortium | |||
|first= | |||
|init= | |||
|author-link= | |||
|etal=no | |||
|title=Structure, function and diversity of the healthy human microbiome | |||
|trans-title= | |||
|language= | |||
|journal=Nature | |||
|location= | |||
|date=2012-06-13 | |||
|volume=486 | |||
|issue=7402 | |||
|article= | |||
|pages=207-14 | |||
|url=https://www.nature.com/articles/nature11234 | |||
|archived= | |||
|quote= | |||
|pubmedID=22699609 | |||
|pubmedCID=3564958 | |||
|DOI=10.1038/nature11234 | |||
|accessdate=2023-09-24 | |||
}}</ref> | |||
Segre (2023) pointed out that the microbiome is "good" and contributes to human health in various ways, such as digestion of food and prevention of colonization by pathogens.<ref name="segre2023">{{REFweb | |||
|url=https://www.genome.gov/genetics-glossary/Microbiome | |url=https://www.genome.gov/genetics-glossary/Microbiome | ||
|title=Microbiome | |title=Microbiome | ||
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}}</ref> | }}</ref> | ||
== Penile microbiome == | |||
Mishra et al. (2023) surveyed the microbiome and mycobiome of eleven toilet-trained pediatric patients before and after elective non-therapeutic [[circumcision]]. Circumcision amputates the [[foreskin]] and destroys the [[preputial sac]] where the microbiome is found.<ref name="cold-taylor1999">{{ColdCJ TaylorJR 1999}}</ref> The authors reported a "significant drop" in the bacterial and fungal population after [[circumcision]], but did ''not'' report any improvement in patient health.<ref>{{REFjournal | |||
|last=Mishra | |||
|first= | |||
|init=K | |||
|author-link= | |||
|last2=Isali | |||
|first2= | |||
|init2=I | |||
|author2-link= | |||
|last3=Sidhani | |||
|first3= | |||
|init3=M | |||
|author3-link= | |||
|last4=Prunty | |||
|first4= | |||
|init4=M | |||
|author4-link= | |||
|etal=yes | |||
|title=Characterization of Changes in Penile Microbiome Following Pediatric Circumcision | |||
|trans-title= | |||
|language= | |||
|journal=Eur Urol Focus | |||
|location= | |||
|date=2023-07 | |||
|volume=9 | |||
|issue=4 | |||
|pages=660-80 | |||
|url=https://www.eu-focus.europeanurology.com/article/S2405-4569(22)00290-5/fulltext | |||
|archived= | |||
|quote= | |||
|pubmedID=36566099 | |||
|pubmedCID= | |||
|DOI=10.1016/j.euf.2022.12.007 | |||
|accessdate=2023-09-25 | |||
}}</ref> | |||
{{SEEALSO}} | |||
* [[Immunological and protective function of the foreskin]] | |||
{{REF}} | {{REF}} | ||
[[Category:Medical term]] | [[Category:Medical term]] | ||
[[Category:Physiology]] | [[Category:Physiology]] | ||
Latest revision as of 13:31, 26 April 2024
The microbiome is the complete genetic content of all the microorganisms that typically inhabit a particular environment, especially a site on or in the body, such as the skin or the gastrointestinal tract.[1]
The Human Microbiome Project Consortium (2012) reported a remarkable diversity in the healthy human microbiome.[2]
Segre (2023) pointed out that the microbiome is "good" and contributes to human health in various ways, such as digestion of food and prevention of colonization by pathogens.[3]
Penile microbiome
Mishra et al. (2023) surveyed the microbiome and mycobiome of eleven toilet-trained pediatric patients before and after elective non-therapeutic circumcision. Circumcision amputates the foreskin and destroys the preputial sac where the microbiome is found.[4] The authors reported a "significant drop" in the bacterial and fungal population after circumcision, but did not report any improvement in patient health.[5]
See also
References
- ↑
microbiome
, The Free Dictionary by Farlex. Retrieved 24 September 2023. - ↑
Human Microbiome Project Consortium. Structure, function and diversity of the healthy human microbiome. Nature. 13 June 2012; 486(7402): 207-14. PMID. PMC. DOI. Retrieved 24 September 2023.
- ↑ Segre, Julie (23 September 2023).
Microbiome
, National Human Genome Research Institute. Retrieved 24 September 2023. - ↑ Cold CJ, Taylor JR. The prepuce. BJU Int. January 1999; 83, Suppl. 1: 34-44. PMID. DOI. Retrieved 8 July 2021.
- ↑ Mishra K, Isali I, Sidhani M, Prunty M, et al. Characterization of Changes in Penile Microbiome Following Pediatric Circumcision. Eur Urol Focus. July 2023; 9(4): 660-80. PMID. DOI. Retrieved 25 September 2023.
