Difference between revisions of "Microbiome"

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The '''microbiome''' is the complete genetic content of all the microorganisms that typically inhabit a particular environment, especially a site on or in the body, such as the skin or the gastrointestinal tract.<ref>{{REFweb
 
The '''microbiome''' is the complete genetic content of all the microorganisms that typically inhabit a particular environment, especially a site on or in the body, such as the skin or the gastrointestinal tract.<ref>{{REFweb
 
  |url=https://medical-dictionary.thefreedictionary.com/Microbiome
 
  |url=https://medical-dictionary.thefreedictionary.com/Microbiome
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Segre (2023) points out that the microbiome is "good" and contributes to human health in various ways, such as digestion of food and prevention of colonization by pathogens.<ref name="segre2023">{{REFweb
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The Human Microbiome Project Consortium (2012) reported a remarkable diversity in the healthy human microbiome.<ref>{{REFjournal
|url=https://www.genome.gov/genetics-glossary/Microbiome
 
|title=Microbiome
 
|last=Segre
 
|first=Julie
 
|init=
 
|publisher=National Human Genome Research Institute
 
|date=2023-09-23
 
|accessdate=2023-09-24
 
}}</ref>
 
 
 
The Human Microbiome Project Consortium reported a remarkable diversity in the healthy human microbiome.<ref>{{REFjournal
 
 
  |last=Human Microbiome Project Consortium
 
  |last=Human Microbiome Project Consortium
 
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  |accessdate=2023-09-24
 
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Segre (2023) pointed out that the microbiome is "good" and contributes to human health in various ways, such as digestion of food and prevention of colonization by pathogens.<ref name="segre2023">{{REFweb
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|url=https://www.genome.gov/genetics-glossary/Microbiome
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|title=Microbiome
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|last=Segre
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|first=Julie
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|init=
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|publisher=National Human Genome Research Institute
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|date=2023-09-23
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|accessdate=2023-09-24
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}}</ref>
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== Penile microbiome ==
 
== Penile microbiome ==
 
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Mishra et al. (2023) surveyed the microbiome and mycobiome of eleven toilet-trained pediatric patients before and after elective non-therapeutic [[circumcision]]. Circumcision amputates the [[foreskin]] and destroys the [[preputial sac]] where the microbiome is found.<ref name="cold-taylor1999">{{ColdCJ TaylorJR 1999}}</ref> The authors reported a "significant drop" in the bacterial and fungal population after [[circumcision]], but did ''not'' report any improvement in patient health.<ref>{{REFjournal
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|last=Mishra
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|first=
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|init=K
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|author-link=
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|last2=Isali
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|init2=I
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|last3=Sidhani
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|last4=Prunty
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|title=Characterization of Changes in Penile Microbiome Following Pediatric Circumcision
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|journal=Eur Urol Focus
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|location=
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|date=2023-07
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|volume=9
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|issue=4
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|pages=660-80
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|url=https://www.eu-focus.europeanurology.com/article/S2405-4569(22)00290-5/fulltext
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|archived=
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|quote=
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|pubmedID=36566099
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|DOI=10.1016/j.euf.2022.12.007
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|accessdate=2023-09-25
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}}</ref>
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{{SEEALSO}}
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* [[Immunological and protective function of the foreskin]]
 
{{REF}}
 
{{REF}}
  
 
[[Category:Medical term]]
 
[[Category:Medical term]]
 
[[Category:Physiology]]
 
[[Category:Physiology]]

Latest revision as of 14:31, 26 April 2024

The microbiome is the complete genetic content of all the microorganisms that typically inhabit a particular environment, especially a site on or in the body, such as the skin or the gastrointestinal tract.[1]

The Human Microbiome Project Consortium (2012) reported a remarkable diversity in the healthy human microbiome.[2]

Segre (2023) pointed out that the microbiome is "good" and contributes to human health in various ways, such as digestion of food and prevention of colonization by pathogens.[3]

Penile microbiome

Mishra et al. (2023) surveyed the microbiome and mycobiome of eleven toilet-trained pediatric patients before and after elective non-therapeutic circumcision. Circumcision amputates the foreskin and destroys the preputial sac where the microbiome is found.[4] The authors reported a "significant drop" in the bacterial and fungal population after circumcision, but did not report any improvement in patient health.[5]

See also

References

  1. REFweb microbiome, The Free Dictionary by Farlex. Retrieved 24 September 2023.
  2. REFjournal Human Microbiome Project Consortium. Structure, function and diversity of the healthy human microbiome. Nature. 13 June 2012; 486(7402): 207-14. PMID. PMC. DOI. Retrieved 24 September 2023.
  3. REFweb Segre, Julie (23 September 2023). Microbiome, National Human Genome Research Institute. Retrieved 24 September 2023.
  4. REFjournal Cold CJ, Taylor JR. The prepuce. BJU Int. January 1999; 83, Suppl. 1: 34-44. PMID. DOI. Retrieved 8 July 2021.
  5. REFjournal Mishra K, Isali I, Sidhani M, Prunty M, et al. Characterization of Changes in Penile Microbiome Following Pediatric Circumcision. Eur Urol Focus. July 2023; 9(4): 660-80. PMID. DOI. Retrieved 25 September 2023.