Histogen - Revision history

WikiModEn2: Wikify.

2022-11-01T13:09:09Z

Wikify.

← Older revision		Revision as of 13:09, 1 November 2022
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	HSC contains proteins, chemicals called growth factors and other substances produced by [[skin]] cells called fibroblasts. The substances are produced when the cells are grown in a low-oxygen environment mimicking an embryonic environment.		HSC contains proteins, chemicals called growth factors and other substances produced by [[skin]] cells called fibroblasts. The substances are produced when the cells are grown in a low-oxygen environment mimicking an embryonic environment.

	The fibroblasts are taken from neonatal foreskins, the byproduct of circumcisions. These are the same cells used by the defunct San Diego company Advanced Tissue Sciences, which produced a living [[skin]] product called Dermagraft It's not a coincidence: Naughton was president and COO of the company. Dermagraft is now being made in San Diego by a subsidiary of Shire, a medical company based in Dublin, Ireland.<ref name="hairgrowth"/> Shire was sold to Takeda Pharmaceutical Company on 8 January 2019.		The fibroblasts are taken from neonatal foreskins, the byproduct of circumcisions. These are the same cells used by the defunct San Diego company [[Advanced Tissue Sciences]], which produced a living [[skin]] product called Dermagraft It's not a coincidence: Naughton was president and COO of the company. Dermagraft is now being made in San Diego by a subsidiary of Shire, a medical company based in Dublin, Ireland.<ref name="hairgrowth"/> Shire was sold to Takeda Pharmaceutical Company on 8 January 2019.

	The United States Patent & Trademark Office issued patent 8,257,947, entitled "Extracellular Matrix Compositions Produced Under Hypoxic Culture Conditions" to Histogen. The patent, which is the Company's first patent issued in the United States, covers Histogen's method of growing cells under low oxygen and suspension conditions, and the process through which the naturally-secreted protein compositions are produced.<ref name="hairgrowth"/>		The United States Patent & Trademark Office issued patent 8,257,947, entitled "Extracellular Matrix Compositions Produced Under Hypoxic Culture Conditions" to Histogen. The patent, which is the Company's first patent issued in the United States, covers Histogen's method of growing cells under low oxygen and suspension conditions, and the process through which the naturally-secreted protein compositions are produced.<ref name="hairgrowth"/>

	On October 2012 Histogen announced preliminary data from a combined Phase 1/2 clinical trial. In this trial, patients aged ~~40-59~~ showed a mean increase of 39 percent in so-called terminal hair, as opposed to fine hair called vellus hair. Hair regrowth took place across all regions of the scalp.<ref name="hairgrowth"/>		On October 2012 Histogen announced preliminary data from a combined Phase 1/2 clinical trial. In this trial, patients aged 40–59 showed a mean increase of 39 percent in so-called terminal hair, as opposed to fine hair called vellus hair. Hair regrowth took place across all regions of the scalp.<ref name="hairgrowth"/>

	{{REF}}		{{REF}}

WikiModEn2: Wikify.

2022-07-09T19:22:31Z

Wikify.

← Older revision		Revision as of 19:22, 9 July 2022
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	'''Histogen''' is a biotech company from San Diego founded by [[Gail K. Naughton]]. They are researching an injectable treatment to promote hair growth called Hair Stimulating Complex, or HSC. This treatment is manufactured using harvested infant foreskins removed by circumcision.<ref name="hairgrowth">{{REFweb		'''Histogen''' is a biotech company from San Diego founded by [[Gail K. Naughton]]. They are researching an injectable treatment to promote hair growth called Hair Stimulating Complex, or HSC. This treatment is manufactured using harvested infant [[Foreskin\| foreskins]] removed by [[circumcision]].<ref name="hairgrowth">{{REFweb
	\|last=		\|last=
	\|first=		\|first=

WikiModEn2: /* Hair Stimulating Complex */ Add sale of Shire.

2022-07-09T19:19:24Z

Hair Stimulating Complex: Add sale of Shire.

← Older revision		Revision as of 19:19, 9 July 2022
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	HSC contains proteins, chemicals called growth factors and other substances produced by [[skin]] cells called fibroblasts. The substances are produced when the cells are grown in a low-oxygen environment mimicking an embryonic environment.		HSC contains proteins, chemicals called growth factors and other substances produced by [[skin]] cells called fibroblasts. The substances are produced when the cells are grown in a low-oxygen environment mimicking an embryonic environment.

	The fibroblasts are taken from neonatal foreskins, the byproduct of circumcisions. These are the same cells used by the defunct San Diego company Advanced Tissue Sciences, which produced a living [[skin]] product called Dermagraft It's not a coincidence: Naughton was president and COO of the company. Dermagraft is now being made in San Diego by a subsidiary of Shire, a medical company based in Dublin, Ireland.<ref name="hairgrowth"/>		The fibroblasts are taken from neonatal foreskins, the byproduct of circumcisions. These are the same cells used by the defunct San Diego company Advanced Tissue Sciences, which produced a living [[skin]] product called Dermagraft It's not a coincidence: Naughton was president and COO of the company. Dermagraft is now being made in San Diego by a subsidiary of Shire, a medical company based in Dublin, Ireland.<ref name="hairgrowth"/> Shire was sold to Takeda Pharmaceutical Company on 8 January 2019.

	The United States Patent & Trademark Office issued patent 8,257,947, entitled "Extracellular Matrix Compositions Produced Under Hypoxic Culture Conditions" to Histogen. The patent, which is the Company's first patent issued in the United States, covers Histogen's method of growing cells under low oxygen and suspension conditions, and the process through which the naturally-secreted protein compositions are produced.<ref name="hairgrowth"/>		The United States Patent & Trademark Office issued patent 8,257,947, entitled "Extracellular Matrix Compositions Produced Under Hypoxic Culture Conditions" to Histogen. The patent, which is the Company's first patent issued in the United States, covers Histogen's method of growing cells under low oxygen and suspension conditions, and the process through which the naturally-secreted protein compositions are produced.<ref name="hairgrowth"/>

WikiAdmin: wikify skin

2021-12-27T14:44:57Z

wikify skin

← Older revision		Revision as of 14:44, 27 December 2021
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	== Hair Stimulating Complex ==		== Hair Stimulating Complex ==

	HSC contains proteins, chemicals called growth factors and other substances produced by skin cells called fibroblasts. The substances are produced when the cells are grown in a low-oxygen environment mimicking an embryonic environment.		HSC contains proteins, chemicals called growth factors and other substances produced by [[skin]] cells called fibroblasts. The substances are produced when the cells are grown in a low-oxygen environment mimicking an embryonic environment.

	The fibroblasts are taken from neonatal foreskins, the byproduct of circumcisions. These are the same cells used by the defunct San Diego company Advanced Tissue Sciences, which produced a living skin product called Dermagraft It's not a coincidence: Naughton was president and COO of the company. Dermagraft is now being made in San Diego by a subsidiary of Shire, a medical company based in Dublin, Ireland.<ref name="hairgrowth"/>		The fibroblasts are taken from neonatal foreskins, the byproduct of circumcisions. These are the same cells used by the defunct San Diego company Advanced Tissue Sciences, which produced a living [[skin]] product called Dermagraft It's not a coincidence: Naughton was president and COO of the company. Dermagraft is now being made in San Diego by a subsidiary of Shire, a medical company based in Dublin, Ireland.<ref name="hairgrowth"/>

	The United States Patent & Trademark Office issued patent 8,257,947, entitled "Extracellular Matrix Compositions Produced Under Hypoxic Culture Conditions" to Histogen. The patent, which is the Company's first patent issued in the United States, covers Histogen's method of growing cells under low oxygen and suspension conditions, and the process through which the naturally-secreted protein compositions are produced.<ref name="hairgrowth"/>		The United States Patent & Trademark Office issued patent 8,257,947, entitled "Extracellular Matrix Compositions Produced Under Hypoxic Culture Conditions" to Histogen. The patent, which is the Company's first patent issued in the United States, covers Histogen's method of growing cells under low oxygen and suspension conditions, and the process through which the naturally-secreted protein compositions are produced.<ref name="hairgrowth"/>

WikiAdmin: using singular name for category

2021-11-29T13:13:49Z

using singular name for category

← Older revision		Revision as of 13:13, 29 November 2021
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	[[Category:Company]]		[[Category:Company]]
	[[Category:Financial gain]]		[[Category:Financial gain]]
	[[Category:Foreskin ~~products~~]]		[[Category:Foreskin product]]

	[[Category:From CircLeaks]]		[[Category:From CircLeaks]]

WikiAdmin: adjusted category

2021-11-09T19:09:02Z

adjusted category

← Older revision		Revision as of 19:09, 9 November 2021
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	{{REF}}		{{REF}}

	[[Category:~~Organizations~~]]		[[Category:Company]]
	[[Category:Financial gain]]		[[Category:Financial gain]]
	[[Category:Foreskin products]]		[[Category:Foreskin products]]

WikiAdmin at 10:38, 9 February 2020

2020-02-09T10:38:06Z

← Older revision		Revision as of 10:38, 9 February 2020
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	On October 2012 Histogen announced preliminary data from a combined Phase 1/2 clinical trial. In this trial, patients aged 40-59 showed a mean increase of 39 percent in so-called terminal hair, as opposed to fine hair called vellus hair. Hair regrowth took place across all regions of the scalp.<ref name="hairgrowth"/>		On October 2012 Histogen announced preliminary data from a combined Phase 1/2 clinical trial. In this trial, patients aged 40-59 showed a mean increase of 39 percent in so-called terminal hair, as opposed to fine hair called vellus hair. Hair regrowth took place across all regions of the scalp.<ref name="hairgrowth"/>

	~~== Gail K. Naughton ==~~
	Naughton was president and COO of [[Advanced Tissue Sciences]], which produced a living skin product call [[Dermagraft]] used to help healing of diabetic foot ulcers. Dermagraft is now being made in San Diego by a subsidiary of [[Shire]], a medical company based in Dublin, Ireland.

	~~Naughton founded Histogen in 2007, when she was dean of San Diego State University's College of Business Administration. Naughton, who had been dean since 2002, left in 2010 to focus on Histogen.~~
	~~<ref>{{REFweb~~
	~~\|last=~~
	~~\|first=~~
	~~\|date=2012-09-05~~
	~~\|title=U.S. Patent issued for Histogen's Novel Cell Growth Process~~
	~~\|url=http://www.histogen.com/aboutus/news_events.htm#37~~
	~~\|publisher=Histogen~~
	~~\|accessdate=2012-11-16~~
	~~}}</ref>~~

	{{REF}}		{{REF}}

WikiAdmin: add interlanguage link

2019-11-22T20:37:51Z

add interlanguage link

← Older revision		Revision as of 20:37, 22 November 2019
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	[[Category:From CircLeaks]]		[[Category:From CircLeaks]]
	[[Category:From IntactWiki]]		[[Category:From IntactWiki]]

			[[de:{{FULLPAGENAME}}]]

WikiAdmin: decapitalize category names

2019-10-19T18:29:41Z

decapitalize category names

← Older revision		Revision as of 18:29, 19 October 2019
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	'''Histogen''' is a biotech company from San Diego founded by [[Gail K. Naughton]]. They are researching an injectable treatment to promote hair growth called Hair Stimulating Complex, or HSC. This treatment is manufactured using harvested infant foreskins removed by circumcision.<ref name="hairgrowth">{{REFweb		'''Histogen''' is a biotech company from San Diego founded by [[Gail K. Naughton]]. They are researching an injectable treatment to promote hair growth called Hair Stimulating Complex, or HSC. This treatment is manufactured using harvested infant foreskins removed by circumcision.<ref name="hairgrowth">{{REFweb
	\| last=		\|last=
	\| first=		\|first=
	\| date=2012-10-19		\|date=2012-10-19
	\| title=Hair growth treatment works, says San Diego's Histogen		\|title=Hair growth treatment works, says San Diego's Histogen
	\| url=http://www.utsandiego.com/news/2012/oct/19/hair-growth-treatment-safe-shows-signs-working-say/		\|url=http://www.utsandiego.com/news/2012/oct/19/hair-growth-treatment-safe-shows-signs-working-say/
	\| publisher=UT San Diego		\|publisher=UT San Diego
	\| accessdate=2012-11-16		\|accessdate=2012-11-16
	}}</ref>		}}</ref>

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	Naughton founded Histogen in 2007, when she was dean of San Diego State University's College of Business Administration. Naughton, who had been dean since 2002, left in 2010 to focus on Histogen.		Naughton founded Histogen in 2007, when she was dean of San Diego State University's College of Business Administration. Naughton, who had been dean since 2002, left in 2010 to focus on Histogen.
	<ref>{{REFweb		<ref>{{REFweb
	\| last=		\|last=
	\| first=		\|first=
	\| date=2012-09-05		\|date=2012-09-05
	\| title=U.S. Patent issued for Histogen's Novel Cell Growth Process		\|title=U.S. Patent issued for Histogen's Novel Cell Growth Process
	\| url=http://www.histogen.com/aboutus/news_events.htm#37		\|url=http://www.histogen.com/aboutus/news_events.htm#37
	\| publisher=Histogen		\|publisher=Histogen
	\| accessdate=2012-11-16		\|accessdate=2012-11-16
	}}</ref>		}}</ref>

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	[[Category:Organizations]]		[[Category:Organizations]]
	[[Category:Financial ~~Gain~~]]		[[Category:Financial gain]]
	[[Category:Foreskin ~~Products~~]]		[[Category:Foreskin products]]

	[[Category:From CircLeaks]]		[[Category:From CircLeaks]]
	[[Category:From IntactWiki]]		[[Category:From IntactWiki]]

WikiAdmin at 14:55, 14 September 2019

2019-09-14T14:55:00Z

← Older revision		Revision as of 14:55, 14 September 2019
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	[[Category:Financial Gain]]		[[Category:Financial Gain]]
	[[Category:Foreskin Products]]		[[Category:Foreskin Products]]
	~~[[Category:CircLeaks]]~~

			[[Category:From CircLeaks]]
	[[Category:From IntactWiki]]		[[Category:From IntactWiki]]