Preputial mucosa: Difference between revisions

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The '''preputial mucosa''' of the [[penis]] is the epithelium of the inside of the prepuce, or [[foreskin]]. To differentiate it from the cutaneous skin of the outside of the [[Foreskin|prepuce]], it is sometimes referred to as the '''inner mucosa'''. It starts at the mucocutaneous junction at the tip of the [[Foreskin|prepuce]] and continues to the coronal sulcus (groove behind the [[glans penis]]), where it meets the epithelium of the glans and  penile shaft.<ref name="cold-taylor1999">{{ColdCJ TaylorJR 1999}}</ref> The preputial mucosa is devoid of hair, as is the cutaneous surface.<ref name="taylor1996">{{TaylorJR LockwoodAP TaylorAJ 1996}}</ref>
The '''preputial mucosa''' of the [[penis]] is the epithelium of the inside of the prepuce, or [[foreskin]]. To differentiate it from the cutaneous [[skin]] of the outside of the [[Foreskin|prepuce]], it is sometimes referred to as the '''inner mucosa'''. It starts at the mucocutaneous junction at the tip of the [[Foreskin|prepuce]] and continues to the coronal sulcus (groove behind the [[glans penis]]), where it meets the epithelium of the glans and  penile shaft.<ref name="cold-taylor1999">{{ColdCJ TaylorJR 1999}}</ref> The preputial mucosa is devoid of hair, as is the cutaneous surface.<ref name="taylor1996">{{TaylorJR LockwoodAP TaylorAJ 1996}}</ref> The preputial mucosa includes the [[ridged band]] and is richly endowed with [[Meissner's corpuscles]].<ref name="garcía-mesa2021">{{REFjournal
|last=García-Mesa
|first=Yolanda
|init=
|author-link=
|last2=García-Piqueras
|first2=Jorge
|init2=
|author2-link=
|last3=Cobo
|first3=Ramón
|init3=
|author3-link=
|last4=Martín-Cruces
|first4=José
|init4=
|author4-link=
|last5=Suazo
|first5=Iván
|init5=
|author5-link=
|last6=García-Suárez
|first6=Olivia
|init6=
|author6-link=
|last7=Feito
|first7=Jorge
|init7=
|author7-link=
|last8=
|first8=Vega
|init8=José A.
|author8-link=
|etal=no
|title=Sensory innervation of the human male prepuce: Meissner's corpuscles predominate
|trans-title=
|language=
|journal=Journal of Anatomy
|location=
|date=2021-10
|volume=239
|issue=4
|article=
|page=
|pages=892-902
|url=https://onlinelibrary.wiley.com/doi/full/10.1111/joa.13481
|archived=
|quote=
|pubmedID=34120333
|pubmedCID=8450466
|DOI=10.1111/joa.13481
|accessdate=2022-03-18
}}</ref>
 
[[Paul M. Fleiss| Fleiss]] et al. (1998) reported the inner [[mucosa]] contains apocrine glands, which secrete cathepsin B, lysozyme, chymotrypsin, neutrophil elastase, and hormones such as androsterone. The first four substances have protective immunological functions.<ref name="fleiss-hodges-vanhowe1998">{{FleissP HodgesF VanHoweRS 1998}}</ref>
 
After [[circumcision]], the residual [[mucosa]] is found between the [[circumcision scar]] and the [[glans penis]]. The [[mucosa]] is no longer moisturized by [[transudation]] from the [[foreskin]] and becomes desiccated and [[Keratinization|keratinized]]. Non-surgical [[foreskin restoration]] helps the mucosa to return to normal by [[dekeratinization]].


Fleiss et al. (1998) report the inner [[mucosa]] contains apocrine glands, which secrete cathepsin B, lysozyme, chymotrypsin, neutrophil elastase, and hormones such as androsterone. The first four substances have protective immunological functions.<ref name="fleiss-hodges-vanhowe1998">{{REFjournal
==Care==
  |last=Fleiss
Birley et al. (1993) recommended that the use of soap and excessive washing inside the [[foreskin]] be avoided.<ref>{{REFjournal
  |init=P
  |last=Birley
  |author-link=Paul M. Fleiss
  |init=HDL
  |last2=Hodges
  |author-link=
  |init2=F
  |last2=Walker
  |author2-link=Frederick M. Hodges
  |init2=MM
  |last3=Van Howe
  |author2-link=
  |init3=RS
  |last3=Luzzi
  |author3-link=Robert S. Van Howe
  |init3=GA
  |title=Immunological functions of the human prepuce
  |author3-link=
  |journal=Sex Trans Infect
|last4=Bell
  |date=1998-10
|init4=R
  |volume=74
|author4-link=
|etal=yes
  |title=Clinical Features and management of recurrent
balanitis; association with atopy and genital
washing]
|trans-title=
|language=
  |journal=Genitourin Med
|location=
  |date=1993-10
  |volume=69
  |issue=5
  |issue=5
  |pages=364-67
  |pages=400-3
  |url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1758142/pdf/v074p00364.pdf
  |url=
  |quote=
  |quote=
  |pubmedID=10195034
  |pubmedID=8244363
  |pubmedCID=
  |pubmedCID=1195128
  |DOI=
  |DOI=10.1136/sti.69.5.400
  |accessdate=2019-12-01
  |accessdate=2022-02-08
}}</ref>
}}</ref>


After circumcision, the residual [[mucosa]] is found between the [[circumcision scar]] and the [[glans penis]]. The [[mucosa]] is no longer moisturized by [[transudation]] from the [[foreskin]] and becomes desiccated.
{{SEEALSO}}


{{SEEALSO}}
* [[Immunological and protective function of the foreskin]]
* [[Jojoba]]
* [[Pheromone]]
* [[Preputial sac]]
* [[Ridged band]]
* [[Ridged band]]


{{LINKS}}
* {{REFweb
|url=http://www.cirp.org/library/hygiene/
|archived=
|title=Penile hygiene for intact (non-circumcised) males
|trans-title=
|language=
|last=Hill
|first=George
|author-link=
|publisher=Circumcision Reference Library
|website=
|date=2004-08-08
|accessdate=2022-03-05
|format=
|quote=The foreskin keeps the mucosal surfaces moist, emolliated, and maintains optimum health, while preventing drying, and keratinization of the mucosa. The sub-preputial moisture contains pathogen-fighting substances.
}}
* {{URLwikipedia|Preputial_mucosa|Preputial mucosa}}
{{REF}}
{{REF}}


[[Category:Foreskinned life]]
[[Category:Genital]]
[[Category:Genital]]
[[Category:Penile anatomy]]
[[Category:Penile anatomy]]
[[Category:Foreskin anatomy]]
[[Category:Foreskin anatomy]]
[[de:Präputialschleimhaut]]