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Two separate very-large-scale population based studies found no relationship between circumcision status and the risk of contracting [[HIV]] infection.
Two separate very-large-scale population based studies found no relationship between circumcision status and the risk of contracting [[HIV]] infection:


Mayan et al. (2021) carried out a massive empirical study of the male population of the province of Ontario, [[Canada]] (569,950 males), of whom 203,588 (35.7%) were circumcised between 1991 and 2017. The study concluded that circumcision status is not related to risk of [[HIV]] infection.<ref name="mayan2021">{{REFjournal
# Mayan et al. (2021) carried out a massive empirical study of the male population of the province of Ontario, [[Canada]] (569,950 males), of whom 203,588 (35.7%) were circumcised between 1991 and 2017. The study concluded that circumcision status is not related to risk of [[HIV]] infection.<ref name="mayan2021">{{REFjournal
  |last=Mayan
  |last=Mayan
  |first=Madhur
  |first=Madhur
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  |accessdate=2021-11-20
  |accessdate=2021-11-20
}}</ref>
}}</ref>
 
# [[Morten Frisch]] and Jacob Simonsen (2021) carried out a large scale empirical population study in [[Denmark]] of 855,654 males regarding the alleged value of male circumcision in preventing [[HIV]] and other sexually transmitted infections in men. They found that circumcised men have a higher rate of STI and [[HIV]] infection overall than intact men.<ref name="frisch2021">{{FrischM SimonsenJ 2021}}</ref>
[[Morten Frisch]] and Jacob Simonsen (2021) carried out a large scale empirical population study in [[Denmark]] of 855,654 males regarding the alleged value of male circumcision in preventing [[HIV]] and other sexually transmitted infections in men. They found that circumcised men have a higher rate of STI and [[HIV]] infection overall than intact men.<ref name="frisch2021">{{REFjournal
|last=Frisch
|first=Morten
|init=
|author-link=Morten Frisch
|last2=Simonsen
|first2=Jacob
|init2=
|author2-link=
|etal=no
|title=Non-therapeutic male circumcision in infancy or childhood and risk of human immunodeficiency virus and other sexually transmitted infections: national cohort study in Denmark
|trans-title=
|language=
|journal=Eur J Epidemiol
|location=
|date=2021-09-26
|volume=Published online ahead of print
|issue=
|article=
|page=
|pages=
|url=https://link.springer.com/article/10.1007/s10654-021-00809-6
|archived=
|quote=
|pubmedID=34564796
|pubmedCID=
|DOI=10.1007/s10654-021-00809-6
|accessdate=2021-11-20
}}</ref>


There now is credible evidence that the massive, expensive African circumcision programs have ''not'' been effective in preventing [[HIV]] infection.
There now is credible evidence that the massive, expensive African circumcision programs have ''not'' been effective in preventing [[HIV]] infection.