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==Attempts to link lack of circumcision to HIV infection==
==Attempts to link lack of circumcision to HIV infection==


Despite the known [[Immunological and protective function of the foreskin| immunological functions]] of the [[foreskin]], certain [[:Category:Promoter|promoters of male circumcision]] attempted to link HIV infection to lack of [[circumcision]]. Three randomized controlled trials (RCTs) were carried out in Africa in an attempt to prove their hypothesis. [[Gregory J. Boyle|Boyle]] & [[George Hill|Hill]] (2011) however studied their reports and found disabling methodological and statistical errors that invalidated their purported findings.<ref name="boyle-hill2011">{{BoyleGJ HillG 2011}}</ref>
Despite the known [[Immunological and protective function of the foreskin| immunological functions]] of the [[foreskin]], certain [[:Category:Promoter|promoters of male circumcision]] attempted to link HIV infection to lack of [[circumcision]]. Three randomized controlled trials (RCTs) were carried out in Africa in an attempt to prove their hypothesis.  
 
Green et al. (2008), in a preliminary report, published a long list of methodological issues with the RCTs.<ref name="green2008">{{REFjournal
|last=Green
|first=Lawrence W
|init=
|author-link=
|last2=McAllister
|first2=Ryan S.
|init2=
|author2-link=
|last3=Peterson
|first3=Kent W.
|init3=
|author3-link=
|last4=Travis
|first4=John W.
|init4=
|author4-link=
|etal=no
|title=Male circumcision is not the HIV ‘vaccine’ we have been waiting for!
|trans-title=
|language=
|journal=Future HIV Therapy
|location=
|date=2008
|volume=2
|issue=3
|article=
|page=
|pages=193-9
|url=http://www.futuremedicine.com/doi/full/10.2217/17469600.2.3.193
|archived=
|quote=
|pubmedID=
|pubmedCID=
|DOI=10.2217/17469600.2.3.193
|accessdate=2021-11-29
}}</ref>
 
[[Gregory J. Boyle|Boyle]] & [[George Hill|Hill]] (2011) studied their reports and found disabling methodological and statistical errors that invalidated their purported findings.<ref name="boyle-hill2011">{{BoyleGJ HillG 2011}}</ref>


[[Robert S. Van Howe|Van Howe]] & [[Gregory J. Boyle|Boyle]] (2018) further elaborated on these findings and suggested possible coordination between the RCTs and hinted at the possibility of fraud.<ref name= "vanhowe2018">{{REFjournal
[[Robert S. Van Howe|Van Howe]] & [[Gregory J. Boyle|Boyle]] (2018) further elaborated on these findings and suggested possible coordination between the RCTs and hinted at the possibility of fraud.<ref name= "vanhowe2018">{{REFjournal