Difference between revisions of "Apligraf"

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Apligraf is a synthetic skin created from harvested foreskins.<ref>{{REFweb
 
Apligraf is a synthetic skin created from harvested foreskins.<ref>{{REFweb
  | quote=Human keratinocytes and fibroblasts are derived from neonatal foreskins
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  |quote=Human keratinocytes and fibroblasts are derived from neonatal foreskins
  | url=http://www.apligraf.com/professional/what_is_apligraf/how_is_it_made/
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  |url=http://www.apligraf.com/professional/what_is_apligraf/how_is_it_made/
  | title=Apligraf: How Is It Made?
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  |title=Apligraf: How Is It Made?
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  | publisher=Organogenesis
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  |publisher=Organogenesis
  | date=
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  | accessdate=2011-03-06
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  |accessdate=2011-03-06
 
}}</ref> It is [[FDA]] approved,<ref>{{REFweb
 
}}</ref> It is [[FDA]] approved,<ref>{{REFweb
  | quote=Apligraf® is the first bio-engineered cell based product to receive FDA approval (in 1998).
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  |quote=Apligraf® is the first bio-engineered cell based product to receive FDA approval (in 1998).
  | url=http://www.organogenesis.com/products/bioactive_woundhealing/apligraf.html
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  |url=http://www.organogenesis.com/products/bioactive_woundhealing/apligraf.html
  | title=Apligraf
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  |title=Apligraf
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  | publisher=Organogenesis
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  |publisher=Organogenesis
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  | accessdate=2011-03-06
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  |accessdate=2011-03-06
 
}}</ref> and it is made and sold by [[Organogenesis]], which a corporation based in Canton, MA. Novartis Pharmaceuticals Corp. has global marketing rights to Apligraf.
 
}}</ref> and it is made and sold by [[Organogenesis]], which a corporation based in Canton, MA. Novartis Pharmaceuticals Corp. has global marketing rights to Apligraf.
  
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Revision as of 18:18, 17 November 2019

Apligraf is a synthetic skin created from harvested foreskins.[1] It is FDA approved,[2] and it is made and sold by Organogenesis, which a corporation based in Canton, MA. Novartis Pharmaceuticals Corp. has global marketing rights to Apligraf.

Apligraph Oral

Organogenesis is presently seeking FDA approval for Apligraph Oral, a foreskin-derived product for the "treatment of surgically treated gingival and alveolar mucosal surface defects in adults."[3]

Sponsor slides: http://www.fda.gov/downloads/advisorycommittees/committeesmeetingmaterials/bloodvaccinesandotherbiologics/cellulartissueandgenetherapiesadvisorycommittee/ucm284480.pdf

References

  1. REFweb Apligraf: How Is It Made?, Organogenesis. Retrieved 6 March 2011.
    Quote: Human keratinocytes and fibroblasts are derived from neonatal foreskins
  2. REFweb Apligraf, Organogenesis. Retrieved 6 March 2011.
    Quote: Apligraf® is the first bio-engineered cell based product to receive FDA approval (in 1998).
  3. REFnews (17 November 2011)."November 17, 2011: Cellular, Tissue and Gene Therapies Advisory Committee Meeting: Transcript", FDA. Retrieved 20 December 2011.