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|first=C.J.
|first=C.J.
adjusted REFjournal
Anatomical investigations have identified the prepuce as a primary erogenous zone in humans.<ref name="ErogenousZones">{{REFjournal
|last=Winkelmann
|firstinit=R.K.RK
|title="The Erogenous Zones: Their nerve supply and significance"
|journal=Proceedings of the staff meetings of the Mayo Clinic
For over a hundred years, anatomical research has confirmed that both the penile and clitoral prepuce ([[foreskin]]) are richly innervated, specific erogenous tissue with specialised encapsulated (corpuscular) sensory receptors, such as [[Meissner's corpuscles]], Pacinian corpuscles, genital corpuscles, Krause end bulbs, Ruffini corpuscles, and mucocutaneous corpuscles. These receptors transmit sensations of fine touch, pressure, proprioception, and temperature.<ref name="Nervenendigungen">{{REFjournal
|last=Dogiel
|firstinit=A.S.AS
|title=Die Nervenendigungen in der Schleimhaut der äusseren Genitalorgane des Menschen
|trans-title=Nerve endings in a mucous membrane of external genital organs of the human
}}</ref><ref>{{REFjournal
|last=Dogiel
|firstinit=A.S.AS
|title=Über die Nervenendapparate in der Haut des Menschen
|trans-title=About the nerve end apparatuses in the human skin
}}</ref><ref name="Ohmori">{{REFjournal
|last=Ohmori
|firstinit=D.
|title=Über die Entwicklung der Innervation der Genitalapparate als peripheren Aufnahmeapperat der genitalen Reflexe
|trans-title=About development of the innervation of the genital apparatuses as a peripheral recording device of the genital reflexes
}}</ref><ref>{{REFjournal
|last=Yamada
|firstinit=K. |title=Studies in the innervation in tenth month human embryo.
|journal=Tohoku J Exper Med
|year=1951
}}</ref><ref>{{REFjournal
|last=Yamada
|firstinit=K.
|title=On the sensory nerve terminations in clitoris in human adult
|journal=Tohoku J Exper Med
}}</ref><ref name="CutaneousInnervation">{{REFjournal
|last=Winkelmann
|firstinit=R.K.RK
|title=The cutaneous innervation of human newborn prepuce
|journal=Journal of investigative dermatology
}}</ref><ref>{{REFjournal
|last=Winkelmann
|firstinit=R.K.RK
|title=The mucocutaneous end-organ
|journal=Arch Dermatol
}}</ref><ref>{{REFjournal
|last=Krantz
|firstinit=K.E.KE
|title=Innervation of the human vulva and vagina: a microscopic study
|journal=Obstet Gynecol
The Innervation of the foreskin is impressive <ref>{{REFjournal
|last=Moldwin
|firstinit=R.M.RM
|last2=Valderrama
|first2init2=E.
|title=Immunohistochemical analysis of nerve distribution patterns within preputial tissues
|journal=J Urol
* [[Meissner's corpuscles]],<ref name="Mucosa">{{REFjournal
|last=Taylor
|firstinit=J.R.JR
|author-link=John R. Taylor
|last2=Lockwood
|first2init2=A.P.AP
|last3=Taylor
|first3init3=A.J.AJ
|title=The prepuce: Specialized mucosa of the penis and its loss to circumcision
|journal=British Journal of Urology International
* free nerve endings, end bulbs of Krause,<ref name="Nervenendigungen"/><ref name="Depth">{{REFjournal
|last=Bazett
|firstinit=H.C.HC
|last2=McGlone
|first2init2=B.
|last3=Williams
|first3init3=R.G.RG
|last4=Lufkin
|first4init4=H.M.HM
|title=Depth, distribution and probable identification in the prepuce of sensory end-organs concerned in sensations of temperature and touch; thermometric conductivity
|journal=Archives of Neurology and psychiatry
* genital and bulbs <ref>{{REFjournal
|last=Halata
|firstinit=Z.
|last2=Munger
|first2init2=B.L.BL
|title=The neuroanatomical basis for the protopathic sensibility og the human glans penis
|journal=Brain Res
|last=Cauna
|first=Nikolajs
|init=N
|last2=Ross
|first2=Leonard L.
|last2init2=RossLL
|title=The fine structure of [[Meissner's corpuscles|Meissner's touch corpuscles]] of human fingers
|journal=Journal of Cell Biology
}}</ref> They are concentrated in areas of the body denoted as erogenous zones, which include the foreskin, clitoris, lip and nipple.<ref name="ErogenousZones"/> J.R. Taylor (1996) noted their presence in the foreskin,<ref name="Mucosa"/> and C.J. Cold & Taylor (1999) reported "Most of the encapsulated receptors of the foreskin are [[Meissner's corpuscles|Meissner corpuscles]], as they contact the epithelial basement membrane."<ref>{{
REFjournal
|last=Cold
|first2init=J.R.CJ
|last2=Taylor
|init2=JR
|title=The prepuce
|journal=British Journal of Urology International
}}</ref> Early observations were noted by A.S. Dogiel (1893),<ref name="Nervenendigungen"/> D. Ohmori (1924),<ref name="Ohmori"/> and H. C. Bazett (1935),<ref>{{REFjournal
|last=Bazett
|firstinit=H.C.HC
|title=Methods of investigation of sensation in man and the theoretical value of the results obtained
|journal=Proc. A. Research Nerv. & Ment. Dis.
|volume=15
|date=1935
The foreskin has important sexual nerve receptors that are removed during circumcision.<ref name="CutaneousInnervation"/><ref name="ErogenousZones"/><ref name="Mucosa"/><ref>{{REFjournal
|last=Cold
|first2init=J.R.CJ
|last2=Taylor
|init2=JR
|title=The prepuce
|journal=British Journal of Urology International
|pubmedID=10349413
}}</ref> Circumcision removes the most sensitive part of a man's penis. The five most sensitive areas of the penis are on the foreskin. The transitional region from the external to the internal foreskin is the most sensitive region of the fully intact penis, and more sensitive than the most sensitive region of the circumcised penis.<ref name="FineTouchPressure">{{REFjournal
|last=Sorrells
|first=Morris L.
|lastinit=SorrellsML |last2=Snyder
|first2=James L.
|last2init2=SnyderJD
|title=Fine-touch pressure thresholds in the adult penis
|journal=BJU International