Changes

The link between the presence of [[human papillovirus]] (HPV) and genital cancer was established in the 1980s.<ref>zur Hausen H. Genital papillomavirus infections. ''Prog Med Virol'' 1985;32:15-21.</ref><ref>Kaufman RH, Adam E: [[Herpes]] simplex virus and human papilloma virus in the development of cervical carcinoma. ''Clin Obstet Gynecol'' 1986; 3: 678-692</ref><ref>McCance DJ, Kalache A., Ashdown K, et al. [http://www.cirp.org/library/disease/cancer/mccance/ Human papillomavirus types 16 and 18 in carcinomas of the penis from Brazil]. ''Int J Cancer'' 1986:37:55-59</ref><ref>Villa LL, Lopes A. Human papillomavirus DNA sequences in penile carcinomas in Brazil. ''Int J Cancer'' 1986;37(6):853-5.</ref><ref>McCance DJ. Human papillomaviruses and cancer. ''Biochem Biophys Acta'' 1986;823:195-206</ref><ref>Barrasso R, De Brux J, Croissant O, et al. High prevalence of papillomavirus-associated penile intraepithelial neoplasia in sexual partners of women with cervical intraepithelial neoplasia. ''N Engl J Med'' 1987 Oct 8;317(15):916-23.</ref> Poland identified human papilloma virus (HPV) types 16 and 18 as the cause of penile and cervical cancers in 1990, and that they could be spread by sexual contact.<ref name="poland1990">Poland RL. [http://www.cirp.org/library/general/poland/ The question of routine neonatal circumcision]. ''N Eng J Med'' 1990; 322:1312-5.</ref> At least one study suggests that circumcised men are at higher risk for HPV infection,<ref name="cook1993">Cook LS, Koutsky LA, Holmes KK. [http://www.cirp.org/library/disease/STD/cook2/ Clinical presentation of genital warts among circumcised and [[uncircumcised ]] heterosexual men attending an urban STD clinic]. ''Genitourin Med'' 1993;69:262-4</ref> making being circumcised a risk factor.