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|DOI=https://doi.org/10.1002/ar.1090570409
|accessdate=2023-05-23
}}</ref> so it cannot be [[Infection| infected]]. The preputial sac will remain closed for a variable number of years.
The preputial sac is lined with [[mucosa]] as is appropriate for an internal organ where moisture is present.<ref name="cold-taylor1999">{{ColdCJ TaylorJR 1999}}</ref> Urine and other sources of moisture are not harmful to it.
}}</ref>, a natural, normal, benign, healthy, and beneficial product of the body, which will collect in the preputial sac.
Wetness in the preputial sac is associated with having a longer [[foreskin| prepuce]].<ref name="ofarrell2008">{{REFjournal
|last=O'Farrell
|first=