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'''{{FULLPAGENAME}}''' is the term applied to the creation of a [[foreskin]] by the application of tissue engineering and regenerative medicine to regeneration of the lost foreskin for those men who have lost their [[foreskin]] to [[circumcision]].
'''{{FULLPAGENAME}}''' is the term applied to the creation of a foreskin for those men who have lost their [[foreskin]] to [[circumcision]] by the application of organ regeneration science.  
   
   
'''{{FULLPAGENAME}}''' remains experimental in the Spring of 2024 as no foreskin has yet been regenerated. It would use a different process from [[foreskin restoration]] as has been [[Epispasm| practiced since ancient times]].
{{FULLPAGENAME}} remains experimental and under development in the Spring of 2024 as no foreskin has yet been regenerated.  


'''{{FULLPAGENAME}}''' has been promoted by [[Vincenzo Aiello]] of Rome, Italy, who has created an Italian charitable organization, [[Foregen]], to advance the development of foreskin regeneration.
{{FULLPAGENAME}} would use a different process from [[foreskin restoration]] as has been [[Epispasm| practiced since ancient times]].


{{FULLPAGENAME}} has been promoted by [[Vincenzo Aiello]] of Rome, Italy, who has created [[Foregen]], an Italian charitable organization, in 2010, to advance the development of foreskin regeneration.
== Progress reports ==
* [[Foregen]] announced in 2018 that it had completed a decellularized extracellular matrix–based biomaterial scaffold, which is to be used in foreskin regeneration.<ref>{{REFjournal
|last=Purpura
|first=Valeria
|init=V
|author-link=
|last2=Bondioli
|first2=Elena
|init2=E
|author2-link=
|last3=Cunningham
|first3=Eric J.
|init3=EC
|author3-link=
|etal=yes
|title=The development of a decellularized extracellular matrix–based biomaterial scaffold derived from human foreskin for the purpose of foreskin reconstruction in circumcised males
|journal=J Tissue Eng
|location=
|date=2018-12-22
|volume=
|issue=
|pages=
|url=https://journals.sagepub.com/doi/full/10.1177/2041731418812613
|quote=
|pubmedID=30622692
|pubmedCID=6304708
|DOI=10.1177/2041731418812613
|accessdate=2024-03-16
}}</ref>
* Aiello (April 2023) announced the successful completion of animal trials using sheep.
* Novatna et al. (2023) compared two different methods of decellularization techniques of human foreskin and found that both methods are satisfactory.<ref>{{REFjournal
|last=Novatna
|first=
|init=O
|author-link=
|last2=Varchulova Novakova,
|first2=
|init2=V
|author2-link=
|last3=Galfiova
|first3=
|init3=P
|author3-link=
|last4=Lorencova
|first4=
|init4=P
|author4-link=
|last5=Klein
|first5=
|init5=M
|author5-link=
|last6=Žiaran
|first6=
|init6=A
|author6-link=
|last7=Kuniakova
|first7=
|init7=M
|author7-link=
|etal=no
|title=Decellularization techniques of human foreskin for tissue engineering application
|trans-title=
|language=
|journal=Physiol Res
|location=
|date=2023-10-27
|volume=72
|issue=S3
|article=
|page=
|pages=S287-S297
|url=https://www.biomed.cas.cz/physiolres/pdf/2023/72_S287.pdf
|archived=
|quote=
|pubmedID=37888972
|pubmedCID=10669949
|DOI=10.33549/physiolres.935185
|doi=
|accessdate=2023-03-16
}}</ref>
== Video ==
=== Progress update April 2023 (by Mr. Aiello) ===
<youtube>v=SIsIg1gm5N8</youtube>
== Economics ==
[[Brendon Marotta]] estimates that the market for foreskin regeneration may be more than $200 billion.<ref name="marotta2023">{{REFweb
|url=https://www.hegemonmedia.com/p/survey-data-shows-the-foreskin-regeneration
|title=Survey Data Shows The Foreskin Regeneration Market Is Over 200 Billion Dollars
|last=Marotta
|first=Brendon
|init=
|author-link=Brendon Marotta
|publisher=Hegemon Media
|date=2023-06-28
|accessdate=2024-03-16
}}</ref>
{{SEEALSO}}
* [[Intro to Foregen - non-profit agency to promote foreskin regeneration]]
* [[Medical_literature_about_foreskin_restoration#Foreskin_regeneration| Foreskin regeneration medical articles]]
{{LINKS}}
* {{REFweb
|url=https://www.nibib.nih.gov/science-education/science-topics/tissue-engineering-and-regenerative-medicine
|title=Tissue engineering and regenerative medicine
|last=Anonymous
|first=
|init=
|publisher=National Institutes of Health,
|date=
|accessdate=2024-03-18
}}
* {{URLwikipedia|Regeneration_in_humans|Regeneration in humans|2024-06-14}}
{{REF}}


[[Category:Body modification]]
[[Category:Body modification]]
[[Category:Foregen]]
[[Category:Medical term]]
[[Category:Medical term]]
[[Category:term]]
[[Category:Term]]
 
[[Category:Italy]]
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