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'''Foregen'''’s goal is to heal the physical detriment that that is inherent to [[circumcision]].
[[Image:Foregen logo.png|right]]


[[Image:Foregen logo.png]]
'''Foregen''' is a registered Italian charity. Foregen was founded by Sig. [[Vincenzo Aiello]] of Italy to promote and arrange a clinical trial that would use regenerative techniques to regrow the tissue removed at circumcision. Foregen's goal is to heal the physical loss of functional tissue that is inherent to [[circumcision]]. Foregen's principal office is at Via Campi Flegrei 59, 00141 Rome, Italy.
==History==
After dismissing many unsatisfactory proposals from research institutions, Foregen decided to conduct its own research and clinical trials. Foregen has applied regenerative techniques to animal foreskins and will continue research on adult human foreskins.
 
Foregen announced in 2018 that it had completed a decellularized extracellular matrix–based biomaterial scaffold, which is to be used in foreskin regeneration.<ref>{{REFjournal
|last=Purpura
|first=Valeria
|init=V
|author-link=
|last2=Bondioli
|first2=Elena
|init2=E
|author2-link=
|last3=Cunningham
|first3=Eric J.
|init3=EC
|author3-link=
|etal=yes
|title=The development of a decellularized extracellular matrix–based biomaterial scaffold derived from human foreskin for the purpose of foreskin reconstruction in circumcised males
|journal=J Tissue Eng
|location=
|date=2018-12-22
|volume=
|issue=
|pages=
|url=https://journals.sagepub.com/doi/full/10.1177/2041731418812613
|quote=
|pubmedID=30622692
|pubmedCID=6304708
|DOI=10.1177/2041731418812613
|accessdate=2020-02-09
}}</ref>


Regenerative medical techniques now offer a greater possibility than ever to regrow human tissue, especially dermal tissue, lost in prior trauma. Regenerative medicine has been used to recreate vaginas of women with some congenital conditions<ref>{{REFnews
Foregen announced in December 2021 that it is hoped that clinical trials would commence in April 2023.<ref>{{REFweb
|url=https://www.foregen.org/clinical-trials
|title=Human Clinical Trials Application Form
|last=
|first=
|date=2021-12
|accessdate=2021-12-20
}}</ref>
 
==Regenerative medicine==
Regenerative medical techniques now offer a greater possibility than ever to regrow human tissue, especially dermal tissue, lost in prior [[trauma]]. Regenerative medicine has been used to recreate vaginas of women with some congenital conditions<ref>{{REFnews
  |last=Richardson
  |last=Richardson
  |first=Karen
  |first=Karen
Line 68: Line 109:
  |date=2014-04-22
  |date=2014-04-22
  |accessdate=2015-07-15
  |accessdate=2015-07-15
}}</ref>. However, regenerative medicine has not yet been applied to those who have been circumcised and no longer wish to be.
}}</ref>. However, regenerative medicine has not yet been applied to those who have been [[circumcised]], but no longer wish to be.
 
For more information on the science behind Foregen, read: [http://www.foregen.org/science_of_regeneration The science of regeneration]


==History==
Foregen was founded by Mr. [[Vincenzo Aiello]] to promote and arrange a clinical trial that would use regenerative techniques to regrow the tissue removed at circumcision. After dismissing many unsatisfactory proposals from research institutions, Foregen decided to conduct its own research and clinical trials. Foregen has applied regenerative techniques to animal foreskins and will continue research on adult human foreskins.
==Goals==
==Goals==
Foregen’s tasks are:
Foregen’s tasks are:
Line 81: Line 122:
==Foregen is a charity==
==Foregen is a charity==


Foregen™ was created in 2010 thanks to donor funds. Foregen operates in the United States and Europe. Its head office is in Rome, Italy, where it is a registered charity (Reg. No. 6482, Serie 1T, 2010). See original founding documents here. Foregen is also tax-exempt under section 501(c)(3) of the Internal Revenue Code and is headed by a board of charitable directors with participants and donors across both continents and beyond.
Foregen™ was created in 2010 thanks to donor funds. Foregen operates in the [[United States]] and Europe. Its head office is in Rome, Italy, where it is a registered charity (Reg. No. 6482, Serie 1T, 2010). See original founding documents here. Foregen is also tax-exempt under section 501(c)(3) of the Internal Revenue Code and is headed by a board of charitable directors with participants and donors across both continents and beyond.
 
Foreget announced on 19 December 2021 that its cummulative donations had exceeded $1 million.


For more information on the science behind Foregen, read: [http://www.foregen.org/science_of_regeneration The science of regeneration]
== Videos ==
===Foregen Explained: Who We Are and What We Do===
<youtube>v=yJ0rDhoTjmA</youtube>
=== Message from Foregen's president, [[Vincenzo Aiello]] ===
<youtube>2ywXUcSW4kQ</youtube>
=== HUFO - The Missing Piece ===
<youtube>l0o411Lu8Yg</youtube>
===Foregen and the Science of Regeneration===
<youtube>JTOoc8ToSjc</youtube>
 
===Sheep Trials Part 1: Preparing the Sheep and Attaching ECMs===
<youtube>lI8TKqkF4Hw</youtube>
 
===Consultation with Dr. Dan mon O'Dey===
<youtube>5uxBJHiscJ8</youtube>
 
===Vincenzo Aiello announces success of sheep trials===
<youtube>SIsIg1gm5N8</youtube>
===Foreskin Regeneration Nonprofit Raises Half a Million Dollars===
<youtube>v=Az2a17-RQMg</youtube>
===Foreskin sensation===
<youtube>_t7uduP9egk</youtube>
 
==Progress reports==
 
Forgen released the results of a survey on 9 January 2023 which reported that 21 percent of American [[circumcised]] men (more than 18 million) would consider undergoing a procedure to regenerate their [[foreskin]].‍<ref>{{REFweb
|url=https://www.foregen.org/commentarium-articles/5-million-men-more-than-triple-that-over-18-million-american-men-would-consider-regenerating-their-foreskin
|title=5 Million Men? More Than Triple That: Over 18 Million American Men Would Consider Regenerating Their Foreskin.
|last=Serody
|first=Matthew R.
|init=
|publisher=Foregen
|date=2023-01-09
|accessdate=2023-01-11
}}</ref>


==Video==
As of March 2024, Foregen has not yet regenerated a [[foreskin]].


Message from Foregen's president, [[Vincenzo Aiello]].
Some of Foregen's principal employees resigned in 2025 to start a for-profit stock tissue-engineering company named [[Αkroprint]].
<br>
<youtube>2ywXUcSW4kQ</youtube><br><br>


<youtube>l0o411Lu8Yg</youtube>
<br>
== Social media ==
== Social media ==
* [https://www.youtube.com/channel/UCUPHstb4Zzc-e1lbJVrT5HA Youtube Channel]
* [https://www.youtube.com/channel/UCUPHstb4Zzc-e1lbJVrT5HA Youtube channel]
* [https://www.facebook.com/foregen Facebook page]
* {{URL-FBpage|foregen|2021-12-20}}
* [https://twitter.com/foregen Twitter]
* {{URLtwitter|foregen|2021-12-20}}


== Foregen in the media ==
== Foregen in the media ==
* {{REFnews
* {{REFnews
  |title=How One Company Aims to Help Circumcised Men Grow Their Foreskin Back
  |title=How One Company Aims to Help Circumcised Men Grow Their Foreskin Back
Line 124: Line 196:
  |quote=
  |quote=
}}
}}
* {{REFnews
* {{REFnews
  |title=Circumcised? Foregen wants to regrow your foreskin and restore sexual pleasure
  |title=Circumcised? Foregen wants to regrow your foreskin and restore sexual pleasure
Line 137: Line 208:
  |quote=
  |quote=
}}
}}
 
* [http://www.queerty.com/circumcised-men-may-soon-be-able-to-regrow-their-foreskin-thanks-to-new-miracle-therapy-20150219 Queerty: Circumcised Men May Soon Be Able To Regrow Their Foreskin Thanks To New Miracle Therapy]
* [http://www.queerty.com/circumcised-men-may-soon-be-able-to-regrow-their-foreskin-thanks-to-new-miracle-therapy-20150219 Querty: Circumcised Men May Soon Be Able To Regrow Their Foreskin Thanks To New Miracle Therapy]
* [http://www.queerty.com/queerty-readers-respond-to-news-that-men-will-soon-be-able-to-regrow-their-foreskin-20150220 Queerty: Queerty Readers Respond To News That Men Will Soon Be Able To Regrow Their Foreskin]
* [http://www.queerty.com/queerty-readers-respond-to-news-that-men-will-soon-be-able-to-regrow-their-foreskin-20150220 Queerty: Queerty Readers Respond To News That Men Will Soon Be Able To Regrow Their Foreskin]
* [http://www.thegailygrind.com/2015/02/19/circumcised-men-may-soon-able-regrow-foreskin-new-therapy/ The gaily grind: Circumcised Men May Soon Be Able To Regrow Their Foreskin With New Therapy]
* [http://www.thegailygrind.com/2015/02/19/circumcised-men-may-soon-able-regrow-foreskin-new-therapy/ The gaily grind: Circumcised Men May Soon Be Able To Regrow Their Foreskin With New Therapy]
Line 144: Line 214:


{{SEEALSO}}
{{SEEALSO}}
* [https://en.wikipedia.org/wiki/Genital_regeneration Wikipedia: Genital regeneration]
* [[Foreskin]]
* [[Penis]]
* [[Restoration]]
* [[Ridged band]]
* [[Psychological issues of male circumcision]]
* [[Basics of foreskin restoration]]
* [[Surgical foreskin restoration]]
* [[Literature about foreskin restoration]]


{{LINKS}}
{{LINKS}}
* {{URLwebsite|http://www.foregen.org|2019-09-16}}
* {{URLwebsite|http://www.foregen.org|2019-09-16}}
* [https://en.wikipedia.org/wiki/Genital_regeneration Wikipedia: Genital regeneration]


{{REF}}
{{REF}}


[[Category:Under construction]]
[[Category:Foregen]]
[[Category:Foreskin regeneration]]
[[Category:Foreskin restoration]]
[[Category:Foreskin restoration]]


[[Category:From IntactWiki]]
[[Category:From IntactWiki]]
[[de:Foregen]]
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