Stephen Moses: Difference between revisions

RCT in Kenya: Add information on problems with RCTs.
RCT in Kenya: Edit text.
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== RCT in Kenya ==
== RCT in Kenya ==
Of the three {{#tip-text:RCT|Randomized controlled trial}}s being used by the [[WHO]] to endorse circumcision as HIV prevention, Stephen Moses and [[Robert C. Bailey]] headed the {{#tip-text:RCT|Randomized controlled trial}} that was carried out in Kenya.<ref>Bailey RC, Moses S, Parker CB, et al. Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomised controlled trial. Lancet 2007;369:643-56. [http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(07)60312-2/abstract Abstract]</ref> All three trials were funded by the American [[National Institutes of Health]].<ref name='DOC 2008'>{{REFweb
Three trials were funded by the American [[National Institutes of Health]].<ref name='DOC 2008'>{{REFweb
  |quote=...funding from the United States National Institutes of Health to conduct randomized controlled trials ({{#tip-text:RCT|Randomized controlled trial}}s) in Africa.
  |quote=...funding from the United States National Institutes of Health to conduct randomized controlled trials ({{#tip-text:RCT|Randomized controlled trial}}s) in Africa.
  |last=
  |last=
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  |publisher=Doctors Opposing Circumcision
  |publisher=Doctors Opposing Circumcision
  |date=2008
  |date=2008
  |title=The Use of Male Circumcision to Prevent HIV Infection
  |title=HIV/AIDS
  |url=http://www.doctorsopposingcircumcision.org/info/HIVStatement.html
  |url=https://www.doctorsopposingcircumcision.org/for-professionals/alleged-medical-benefits/hivaids/
  |accessdate=2011-03-05
  |accessdate=2020-03-23
}}</ref>
}}</ref>Of the three {{#tip-text:RCT|Randomized controlled trial}}s being used by the [[WHO]] to endorse circumcision as HIV prevention, Stephen Moses and [[Robert C. Bailey]] headed the {{#tip-text:RCT|Randomized controlled trial}} that was carried out in Kenya.<ref>Bailey RC, Moses S, Parker CB, et al. Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomised controlled trial. ''Lancet'' 2007;369:643-56. [http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(07)60312-2/abstract Abstract]</ref> Moses obviously brought his pre-existing bias in favor of male circumcision into the trial, so he did not start from a neutral position.


Boyle & Hill (2011) reviewed the three randomized controlled trials (RCTs) and found disabling methodological and statistical errors in all three. Although a 60 percent ''relative'' reduction in HIV was claimed, the ''absolute'' reduction was a statistically insignificant 1.3 percent.<ref name="boyle-hill2011">{{REFjournal
Boyle & Hill (2011) reviewed the three randomized controlled trials (RCTs) and found disabling methodological and statistical errors in all three. Although a 60 percent ''relative'' reduction in HIV was claimed, the ''absolute'' reduction was a statistically insignificant 1.3 percent.<ref name="boyle-hill2011">{{REFjournal