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* Laser surgery - laser light is used to burn or cut away cancerous cells.
* [[Circumcision]] - cancerous foreskin is removed.
* [[Amputation ]] ([[penectomy]]) - a partial or total removal of the penis, and possibly the associated lymph nodes.
Radiation therapy is usually used adjuvantly with surgery to reduce the risk of recurrence. With earlier stages of penile cancer, a combination of topical chemotherapy and less invasive surgery may be used. More advanced stages of penile cancer usually require a combination of surgery, radiation and chemotherapy.