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Flechsig's error condemned millions of infant girls and boys to acute [[pain]], [[trauma]] and [[shock]] for more than a century and still persists today. Open heart surgery on infants was done without anesthesia. Boys may have suffered more than girls because of the practice of non-therapeutic neonatal [[circumcision]], including the after effects of behavior changes <ref>{{TaddioA KatzJ IlersichAL KorenG 1997}}</ref> and [[PTSD]].