Changes

Stretching the skin beyond normal expansion invokes several mechanotransduction pathways which increase [[mitosis| mitotic]] activity and promote collagen synthesis. As a result, the skin surface area increases.<ref>{{REFjournal |last=Zöllner |first=Alexander M. |author-link= |coauthors=Tepole AB, Kuhl E |title=On the biomechanics and mechanobiology of growing skin |trans-title= |language= |journal=Theoretical Biology |date=2012 |volume=297 |issue= |pages=166-75 |url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278515/ |quote= |pubmedID=3278515 |pubmedCID=22227432 |DOI=10.1016/j.jtbi.2011.12.022 |accessdate=2019-10-10}}</ref>