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The '''President's Emergency Plan For AIDS Relief''' ('''PEPFAR''') was a United States governmental initiative to address the global [[HIV]] epidemic and help save the lives of those suffering from the disease. Launched by U.S. President George W. Bush in 2003 on the advice of [[Anthony Fauci]], PEPFAR has provided more than $85 billion in cumulative funding for [[HIV]]/[[AIDS]] treatment, prevention, and research since its inception, making it the largest global health program focused on a single disease in history. <b>PEPFAR was a failure and has now been terminated by the United States Government that eliminated the United States Agency for International Development (USAID) in 2025in accordance with the recommendation of the Department of Governmental Efficiency ([[DOGE]]).</b>

This document, ''Reimagining PEPFAR's Strategic Direction'', published in September 2022, provides new directions for PEPFAR's fight against the ''HIV'' pandemic. The document is entirely silent on male and female circumcision, although male circumcision was the cornerstone of the previous effort to prevent HIV infection and PEPFAR formerly proudly trumpeted the 2732,700000,000+ circumcisions (AKA genital mutilations) in Africa that it had sponsored. It is unclear if PEPFAR will continue to promote circumcision, which has been demonstrated to be ineffective.<ref name="reimagining2022">{{REFdocument