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Masters & Johnson (1966) in their book, ''Human Sexual Response'', <ref name="masters-johnson1966" /> showed little interest or understanding of the human foreskin. One illustration, labelled normal [[penis]] anatomy, showed a drawing of a penis without a foreskin. A listing of penile pathology in their book included “[[uncircumcised]] penis”! Their work was done in St. Louis, located in the highly circumcised Midwest, and almost all of their subjects were circumcised. Their testing was quite limited. With regard to the foreskin, they said only:
<blockquote>
Routine neurologic testing for both exteroceptive and light tactile discrimination were conducted on the ventral and dorsal surfaces of the penile body, with particular attention directed toward the glans.</blockquote>