Changes

Individuals with 5-ARD are born with male gonads, including testicles and Wolffian structures. They can have normal male external genitalia, ambiguous genitalia, or normal female genitalia, but usually tend towards a female appearance. As a consequence, they are often raised as girls, but usually have a male gender identity. There is a tendency towards a macroclitoris macro[[clitoris]] or micropenis, and the [[urethra ]] may attach to the [[penis| phallus]].

If the condition has not already been diagnosed, it usually becomes apparent at puberty around age twelve with primary amenorrhoea and virilization. This may include descending of the testes, hirsutism (facial/body hair considered normal in males - not to be confused with hypertrichosis), deepening of the voice, and enlargement of the [[clitoris]].

In general, individuals with 5-ARD are capable of producing viable sperm. In individuals with feminized or ambiguous genitalia, the phallus may be capable of ejaculations as well as erections, but may be insufficient for intercourse. Fertility is further compromised by the underdevelopment of [[seminal vesicles ]] and prostate.