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==Population-based studies==
September 2021 saw the publication of two huge population studies on the relationship of [[circumcision ]] and HIV infection:
# Mayan et al. (2021) carried out a massive empirical study of the male population of the province of Ontario, [[Canada]] (569,950 males), of whom 203,588 (35.7%) were [[circumcised]] between 1991 and 2017. The study concluded that circumcision status is not related to risk of HIV infection.<ref name="mayan2021">{{REFjournal
# [[Morten Frisch]] & Jacob Simonsen (2021) carried out a large scale empirical population study in [[Denmark]] of 855,654 males regarding the alleged value of male circumcision in preventing HIV and other sexually transmitted infections in men. They found that [[circumcised]] men have a higher rate of STI and HIV infection overall than [[intact]] men.<ref name="frisch2021">{{FrischM SimonsenJ 2021}}</ref>
No association between lack of circumcision status and risk of HIV infection was foundby either study.
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