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Meissner's corpuscles

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'''Meissner's corpuscles''' are a type of mechanoreceptor discovered by anatomist Georg Meissner ({{LifeData|1829|1905}}) and Rudolf Wagner.<ref name="meissner1905">{{REFweb
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They are a type of nerve ending in the [[skin ]] that is responsible for sensitivity to light touch. In particular, they have their highest sensitivity (lowest threshold) when sensing vibrations between 10 and 50 hertz. They are rapidly adaptive receptors. They are most concentrated in thick hairless [[skin]], especially at the finger pads.
==Description==
Meissner's corpuscles are encapsulated , unmyelinated nerve endings, surrounded by Schwann cells. The encapsulation consists of flattened supportive cells arranged as horizontal lamellae surrounded by a connective tissue capsule. They are found in abundance in the human [[foreskin]].<ref name="meissner2011winkleman1956">{{REFweb |url=http://www.anatomybox.com/meissners-corpuscles/ |title=Meissner’s CorpusclesREFjournal |last=Winkelmann
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|init=RK |author-link= |etal=no |title=The cutaneous innervation of human newborn prepuce |trans-title= |language= |journal=J Invest Dermatol |location= |date=20111956-0401 |volume=26 |issue=1 |article= |page= |pages=53-67 |url=https://www.jidonline.org/article/S0022-202X(15)48804-049/pdf |archived= |quote= |pubmedID=13295637 |pubmedCID= |DOI=10.1038/jid.1956.5 |doi= |format=PDF |accessdate=20202023-1007-2512}}</ref> The encapsulation consists <ref name="garcía-mesa2021">{{REFjournal |last=García-Mesa |first=Yolanda |init= |author-link= |last2=García-Piqueras |first2=Jorge |init2= |author2-link= |last3=Cobo |first3=Ramón |init3= |author3-link= |last4=Martín-Cruces |first4=José |init4= |author4-link= |last5=Suazo |first5=Iván |init5= |author5-link= |last6=García-Suárez |first6=Olivia |init6= |author6-link= |last7=Feito |first7=Jorge |init7= |author7-link= |last8= |first8=Vega |init8=José A. |author8-link= |etal=no |title=Sensory innervation of the human male prepuce: Meissner's corpuscles predominate |trans-title= |language= |journal=Journal of flattened supportive cells arranged as horizontal lamellae surrounded by a connective tissue capsuleAnatomy |location= |date=2021-10 |volume=239 |issue=4 |article= |page= |pages=892-902 |url=https://onlinelibrary.wiley.com/doi/full/10.1111/joa.13481 |archived= |quote= |pubmedID=34120333 |pubmedCID=8450466 |DOI=10.1111/joa.13481 |accessdate=2021-11-15}}</ref>
==Location==
They are distributed on various areas of the [[skin]], but concentrated in areas especially sensitive to light touch, such as the fingers and lips. More specifically, they are primarily located in glabrous (non-hair bearing) [[skin ]] just beneath the epidermis within the dermal papillae.
Taylor, Lockwood, & Taylor (1996) carried out a gross and histological examination of the [[foreskin| prepuce]]. They reported that numerous Meissner's corpuscles are found in a [[ridged band]] area where the Meissner corpuscles are found near the tops of the ridges.<ref name="taylor1996">{{REFjournal |last=Taylor |first=J.R. |author-link=John R. Taylor |last2=Lockwood |first2=A.P. |author2-link= |last3=Taylor |first3=A.J. |title=The prepuce: specialized mucosa of the penis and its loss to circumcision |journal=Brit J Urol |date=TaylorJR LockwoodAP TaylorAJ 1996 |volume=77 |issue= |pages=291-5 |url=https://www.arclaw.org/wp-content/uploads/Taylor-Prepuce-SpecMucosa-BJU-1996.pdf |quote= |pubmedID=8800902 |pubmedCID= |DOI=10.1046/j.1464-410X.1996.85023.x |accessdate=2020-10-25}}</ref>
Cold & Taylor (1999) describe the innervation of the prepuce as follows:
<blockquote>
Although the sensory and autonomic innervation ofthe penis and [[clitoris ]] are similar, there is a remarkabledifference in their encapsulated somatosensory receptors.Sensory receptors can be classified as mechanoreceptors,e.g. Meissner’s corpuscles, Vater-Pacinian cor-puscles (Fig. 5) corpuscles and Merkel cells (Fig. 6); and nocioceptors(free nerve endings). A multitude of names havebeen used to describe these encapsulated receptors, e.g.Krause, Dogiel, genital corpuscles, Endkalpsen and muco-cutaneous end-organs, but the term corpuscular (encapsulated) receptors will be used here to include allof these mechanoreceptors. Most of the encapsulatedreceptors of the prepuce are Meissner corpuscles, as theycontact the epithelial basement membrane.<ref name="cold-taylor1999">{{REFjournalColdCJ TaylorJR 1999}}</ref></blockquote> |last==Sensation==Cold Winkelmann (1959) identified the [[Foreskin|first=Cprepuce]] and the [[glans penis]] (where Meissner's corpuscles are found) as ''specific erogenous zones''.J. |author-link<ref name="winklemann1959">{{WinkelmannRK 1959}}</ref> |last2=Taylor |first2=JSorrells et al.R(2007) used a Semmes-Weinstein monofilament touch-test to map the fine-touch pressure thresholds of the [[penis]]. |author2The areas most sensitive to fine-link=John Rtouch were the tip of the [[foreskin]] the mucocutaneous junction, the [[ridged band]], and the [[frenulum]]. These areas correspond to the location of Meissner's corpuscles. (These areas are not found on the [[circumcised]] [[penis]]. Taylor |title)<ref name=The prepuce"sorrells2007">{{Sorrells etal 2007}}</ref> |journal=BJU Int |dateMost [[intact]] men note that movement of the [[foreskin]] produces a pleasurable sensation.<ref name=1999"garcía-01-01mesa2021" /><ref name="berkeley1993">{{REFbook |volumelast=83 Suppl 1Berkeley |issuefirst=Bud |pagesinit=34-44B |urltitle=https[[Foreskin://onlinelibrary.wiley.com/doi/epdf/10.1046/j.1464-410x.1999.0830s1034.x |quote= |pubmedID=1034941A Closer Look]] |pubmedCIDyear=1993 |DOIpublisher=10.1046/j.1464-410x.1999.0830s1034.x Alyson Books |accessdateisbn=2020-10978-251555832124
}}</ref>
</blockquote>
{{SEEALSO}}
* [[Foreskin sensitivity]]
 
{{LINKS}}
* {{REFdocument
|title=Meissner's Tactile Corpuscle
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|language=English
|url=https://www.anatomyatlases.org/MicroscopicAnatomy/Section06/Plate06123.shtml
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|last=Bergman
|first=Ronald A.
|author-link=
|last2=Afifi
|first2=Adel K.
|author2-link=
|last3=Heidger
|first3=Paul M.
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|publisher=Anatomy Atlases
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|accessdate=2020-10-27
}}
* {{REFweb
|url=https://intactamerica.org/what-do-the-eyelids-lips-fingertips-the-intact-penis-have-in-common/
|title=What Do The Eyelids, Lips, Fingertips & The Intact Penis Have in Common?
|last=Anonymous
|first=
|init=
|publisher=Intact America
|date=2024-02-17
|accessdate=2024-02-18
}}
{{REF}}
 
[[Category:Education]]
[[Category:Physiology]]
[[Category:Male sexuality]]
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