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New England Journal of Medicine

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The research on EMLA and circumcision presented by Taddio et al. was proclaimed as a major advance.<ref>Taddio A, Stevens B, Craig K, Rastogi P, Ben-David S, Shennan A, Mulligan P, Koren G. Efficacy and safety of lidocaine-prilocaine cream for pain during circumcision. N Engl J Med 1997; 336:1197-1201.</ref> When the limitations of this form of local anesthesia was brought to the attention of the editors, they failed to print the criticism (see Abstracts & Analysis). They failed to point out that this form of local anesthesia (EMLA) did not prevent the long term negative behavioral response to pain previously reported in the Lancet. <ref>Taddio A, Katz J, Ilersich AL, Koren G. Effect of neonatal circumcision on pain response during subsequent routine vaccination. Lancet 1997; 349:599-603.</ref> The lack of effects of EMLA on long term negative behavioral changes caused by circumcision was printed in British medical journals.<ref>Taddio A, Katz J, Ilersich AL, Koren G. Effect of neonatal circumcision on pain response during subsequent routine vaccination. Lancet 1997; 349:599-603.</ref><ref>Taddio A, Goldbach M, Ipp M, Stevens B, Koren G Effect of neonatal circumcision on pain responses during vaccination in boys. Lancet 1995; 345:291-2.</ref>
==References==<div class='references-small'><references/></div>{{REF}}
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