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==Honours==
His majesty King George VI recognised his contributions with a knighthood in 1950.<ref>{{URLwikipediaREFweb |url=https://en.wikipedia.org/wiki/1950_Birthday_Honours | title=1950 Birthday birthday Honours |last= |first= |init= |publisher=Wikipedia |date= |accessdate=2023-03-28}}</ref>
The British Paediatric Association created the James Spence Medal, which is awarded annually since 1960 for "outstanding contributions to the advancement or clarification of paediatric knowledge."<ref name="spence">{{REFjournal