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Foregen

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'''[[Image:Foregen'''’s goal is to heal the physical detriment that that is inherent to circumcisionlogo. png|right]]
'''Foregen''' is a registered Italian charity. Foregen was founded by Sig. [[Image:Vincenzo Aiello]] of Italy to promote and arrange a clinical trial that would use regenerative techniques to regrow the tissue removed at circumcision. Foregen logo.png's goal is to heal the physical loss of functional tissue that is inherent to [[circumcision]]. Foregen's principal office is at Via Campi Flegrei 59, 00141 Rome, Italy.==History==After dismissing many unsatisfactory proposals from research institutions, Foregen decided to conduct its own research and clinical trials. Foregen has applied regenerative techniques to animal foreskins and will continue research on adult human foreskins.
Foregen announced in 2018 that it had completed a decellularized extracellular matrix–based biomaterial scaffold, which is to be used in foreskin regeneration.<ref>{{REFjournal |last=Purpura |first=Valeria |init=V |author-link= |last2=Bondioli |first2=Elena |init2=E |author2-link= |last3=Cunningham |first3=Eric J. |init3=EC |author3-link= |etal=yes |title=The development of a decellularized extracellular matrix–based biomaterial scaffold derived from human foreskin for the purpose of foreskin reconstruction in circumcised males |journal=J Tissue Eng |location= |date=2018-12-22 |volume= |issue= |pages= |url=https://journals.sagepub.com/doi/full/10.1177/2041731418812613 |quote= |pubmedID=30622692 |pubmedCID=6304708 |DOI=10.1177/2041731418812613 |accessdate=2020-02-09}}</ref>  Foregen announced in December 2021 that it is hoped that clinical trials would commence in April 2023.<ref>{{REFweb |url=https://www.foregen.org/clinical-trials |title=Human Clinical Trials Application Form |last= |first= |date=2021-12 |accessdate=2021-12-20}}</ref> ==Regenerative medicine==Regenerative medical techniques now offer a greater possibility than ever to regrow human tissue, especially dermal tissue, lost in prior [[trauma]]. Regenerative medicine has been used to recreate vaginas of women with some congenital conditions<ref>{{REFnews | last=Richardson | first=Karen | coauthors= | url=http://www.wakehealth.edu/News-Releases/2014/Laboratory-Grown_Vaginas_Implanted_in_Patients,_Scientists_Report.htm | title=Laboratory-Grown Vaginas Implanted in Patients, Scientists Report | publisher=Wake Forest Baptist Medical Center | workwebsite= | quote= | date=2014-04-10 | accessdate=2015-07-15
}}</ref>. Experiments have been performed to regenerate the penis of rabbits.<ref>{{REFnews
| last=Geggel | first=Laura | coauthors= | url=http://www.cbsnews.com/news/scientists-developing-lab-grown-penis-for-transplant/ | title=Scientists developing lab-grown penis for transplant | publisher=CBS News | workwebsite=LiveScience | quote= | date=2014-10-09 | accessdate=2015-07-15
}}</ref> <ref>{{REFnews
| last= | first= | coauthors= | url=http://www.wakehealth.edu/Research/Urology/Regenerative-Medicine/Engineered-Penile-Erectile-Tissue.htm | title=Engineered Penile Erectile Tissue | publisher=Wake Forest School of Medicine | work= | quote= | date= | accessdate=2015-07-15
}}</ref><ref>{{REFnews
| last=Mohammadi | first=Dara | coauthors= | url=http://www.theguardian.com/education/2014/oct/04/penis-transplants-anthony-atala-interview | title=The lab-grown penis: approaching a medical milestone | publisher=The Guardian | work= | quote= | date=2014-10-04 | accessdate=2015-07-15
}}</ref> Also progress has been made in penile transplants<ref>{{REFnews
| last=Smith | first=David | coauthors= | url=http://www.theguardian.com/world/2015/mar/13/south-africa-man-penis-transplant | title=Man gets world's first successful penis transplant after botched circumcision | publisher=The Guardian | work= | quote= | date=2015-03-13 | accessdate=2015-07-15
}}</ref> <ref>{{REFnews
| last=Feltman | first=Rachel | coauthors= | url=http://www.independent.co.uk/life-style/health-and-families/health-news/man-who-had-worlds-first-penis-transplant-to-become-a-father-10315628.html | title=Man who had world's first penis transplant to become a father | publisher=The Independent | work= | quote= | date=2015-06-12 | accessdate=2015-07-15
}}</ref> and phalloplasties<ref>{{REFnews
| last=Ho | first=Vivian | coauthors= | url=http://www.sfgate.com/health/article/Man-may-be-1st-to-father-child-with-reconstructed-5416853.php | title=Man may be 1st to father child with reconstructed penis | publisher=SFGate | work= | quote= | date=2014-04-22 | accessdate=2015-07-15}}</ref>. However, regenerative medicine has not yet been applied to those who have been [[circumcised and ]], but no longer wish to be.
For more information on the science behind Foregen was founded by Mr. , read: [[Vincenzo Aiello]] to promote and arrange a clinical trial that would use regenerative techniques to regrow the tissue removed at circumcisionhttp://www. After dismissing many unsatisfactory proposals from research institutions, Foregen decided to conduct its own research and clinical trials. Foregen has applied regenerative techniques to animal foreskins and will continue research on adult human foreskinsforegen.org/science_of_regeneration The science of regeneration]
==Goals==
Foregen’s tasks are:
* To experiment with animal tissue to obtain a viable method of foreskin regeneration
* To apply the expirience experience from animal experiments to regenerate human foreskins
* To advance onto clinical trials once Foregen proves that regenerating human foreskin is possible
Foregen™ was created in 2010 thanks to donor funds. ==Foregen operates in the United States and Europe. Its head office is in Rome, Italy, where it is a registered charity (Reg. No. 6482, Serie 1T, 2010). See original founding documents here. Foregen is also tax-exempt under section 501(c)(3) of the internal revenue code and is headed by a board of charitable directors with participants and donors across both continents and beyond.==
For more information on Foregen™ was created in 2010 thanks to donor funds. Foregen operates in the science behind Foregen[[United States]] and Europe. Its head office is in Rome, Italy, where it is a registered charity (Reg. No. 6482, Serie 1T, read: [http://www2010).foregenSee original founding documents here.org/science_of_regeneration The science Foregen is also tax-exempt under section 501(c)(3) of regeneration]the Internal Revenue Code and is headed by a board of charitable directors with participants and donors across both continents and beyond.
== Website ==* http://wwwForeget announced on 19 December 2021 that its cummulative donations had exceeded $1 million.foregen.org/
== Videos ===== Message from Foregen's president, [[Vincenzo Aiello]].===<youtube>2ywXUcSW4kQ</youtube><br><br>
=== HUFO - The Missing Piece ===
<youtube>l0o411Lu8Yg</youtube>
 
===Foregen and the Science of Regeneration===
<youtube>JTOoc8ToSjc</youtube>
 
===Sheep Trials Part 1: Preparing the Sheep and Attaching ECMs===
<youtube>lI8TKqkF4Hw</youtube>
 
===Consultation with Dr. Dan mon O'Dey===
<youtube>5uxBJHiscJ8</youtube>
 
===Vincenzo Aiello announces success of sheep trials===
<youtube>SIsIg1gm5N8</youtube>
 
===Foreskin sensation===
<youtube>_t7uduP9egk</youtube>
 
==Progress reports==
 
Forgen released the results of a survey on 9 January 2023 which reported that 21 percent of American [[circumcised]] men (more than 18 million) would consider undergoing a procedure to regenerate their [[foreskin]].‍<ref>{{REFweb
|url=https://www.foregen.org/commentarium-articles/5-million-men-more-than-triple-that-over-18-million-american-men-would-consider-regenerating-their-foreskin
|title=5 Million Men? More Than Triple That: Over 18 Million American Men Would Consider Regenerating Their Foreskin.
|last=Serody
|first=Matthew R.
|init=
|publisher=Foregen
|date=2023-01-09
|accessdate=2023-01-11
}}</ref>
 
As of March 2024, Foregen has not yet regenerated a [[foreskin]].
== Social media ==
* [https://www.youtube.com/channel/UCUPHstb4Zzc-e1lbJVrT5HA Youtube Channelchannel]* [https://www.facebook.com/{{URL-FBpage|foregen Facebook page]|2021-12-20}}* [https://twitter.com/{{URLtwitter|foregen Twitter]|2021-12-20}}
== Foregen in the media ==
* [{{REFnews |title=How One Company Aims to Help Circumcised Men Grow Their Foreskin Back |url=http://motherboard.vice.com/read/regrowing-foreskins-like-salamander-arms |last=Millican |first=Arika |coauthors= |publisher=Vice |website= |date=2015-02-17 |accessdate=2020-02-09 |quote=}} * {{REFnews |title=Circumcised men may soon be able to REGROW their foreskin: How One Company Aims to Help Circumcised Men Grow Their Foreskin Back]New technique could help increasing number of men angry they were given the procedure* [ |url=http://www.dailymail.co.uk/health/article-2958422/Circumcised-men-soon-able-REGROW-foreskin-New-technique-help-increasing-number-men-angry-given-procedure.html |last=Davies |first=Madlen |coauthors= |publisher=The Daily Mail: |website= |date=2015-02-20 |accessdate=2020-02-09 |quote=}}* {{REFnews |title=Circumcised men may soon be able ? Foregen wants to REGROW their regrow your foreskin: New technique could help increasing number of men angry they were given the procedure]and restore sexual pleasure* [ |url=http://www.mirror.co.uk/news/technology-science/science/circumcised-foregen-wants-regrow-your-5185843 |last=Solon |first=Oliva |coauthors= |publisher=Mirror: Circumcised? Foregen wants to regrow your foreskin and restore sexual pleasure] |website= |date=2015-02-19 |accessdate=2020-02-09 |quote=}}* [http://www.queerty.com/circumcised-men-may-soon-be-able-to-regrow-their-foreskin-thanks-to-new-miracle-therapy-20150219 QuertyQueerty: Circumcised Men May Soon Be Able To Regrow Their Foreskin Thanks To New Miracle Therapy]
* [http://www.queerty.com/queerty-readers-respond-to-news-that-men-will-soon-be-able-to-regrow-their-foreskin-20150220 Queerty: Queerty Readers Respond To News That Men Will Soon Be Able To Regrow Their Foreskin]
* [http://www.thegailygrind.com/2015/02/19/circumcised-men-may-soon-able-regrow-foreskin-new-therapy/ The gaily grind: Circumcised Men May Soon Be Able To Regrow Their Foreskin With New Therapy]
{{SEEALSO}}
* [[Foreskin]]
* [[Penis]]
* [[Restoration]]
* [[Ridged band]]
* [[Psychological issues of male circumcision]]
* [[Basics of foreskin restoration]]
* [[Surgical foreskin restoration]]
* [[Literature about foreskin restoration]]
 
{{LINKS}}
* {{URLwebsite|http://www.foregen.org|2019-09-16}}
* [https://en.wikipedia.org/wiki/Genital_regeneration Wikipedia: Genital regeneration]
{{REF}}
[[Category:Under constructionForegen]]
[[Category:Foreskin restoration]]
[[Category:From IntactWiki]]
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