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The association of HPV transmission with circumcision has been a heavily debated topic for many years. As more recent studies enact more rigorous controls and use larger study groups, the association between circumcision and HPV has become more clear.
A classic 1993 study on HPV came up with the following conclusions: "Uncircumcised men had a lower prevalence of genital warts than circumcised men... The presence of the foreskin may confer non specific protection of the proximal penis from acquisition of HPV infection."
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| last=Cook
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A meta-analysis Performed by Dr. [[Robert Van Howe ]] in 2006 found no significant association between circumcision status and HPV infection. "The medical literature does not support the claim that circumcision reduces the risk for genital HPV infection"<ref>{{REFjournal
| last=Van Howe
| first=Robert S.