Human papillomavirus: Difference between revisions

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A classic 1993 study on HPV came up with the following conclusions: "Uncircumcised men had a lower prevalence of genital warts than circumcised men... The presence of the foreskin may confer non specific protection of the proximal penis from acquisition of HPV infection."
A classic 1993 study on HPV came up with the following conclusions: "Uncircumcised men had a lower prevalence of genital warts than circumcised men... The presence of the foreskin may confer non specific protection of the proximal penis from acquisition of HPV infection."
<ref>{{REFjournal
<ref>{{REFjournal
  | last=Cook
  |last=Cook
  | first=LS
  |first=L.S.
  | coauthors=Koutsky LA, Holmes KK,
  |last2=Koutsky
  | title=Clinical presentation of genital warts among circumcised and uncircumcised heterosexual men attending an urban STD clinic
|first2=L.A.
  | journal=Genitourin Med
|last3=Holmes
  | volume=69
|first4=K.K.
  | issue=4
  |title=Clinical presentation of genital warts among circumcised and uncircumcised heterosexual men attending an urban STD clinic
  | pages=262-4
  |journal=Genitourin Med
  | url=http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1195083/
  |volume=69
  | quote=
  |issue=4
  | pubmedID=
  |pages=262-4
  | pubmedCID=1195083
  |url=http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1195083/
  | DOI=
  |quote=
  | date=1993 Aug
  |pubmedID=
  | accessdate=
  |pubmedCID=1195083
  |DOI=
  |date=1993 Aug
  |accessdate=
}}</ref>
}}</ref>


A meta-analysis performed by Dr. [[Robert Van Howe]] in 2006 found no significant association between circumcision status and HPV infection. "The medical literature does not support the claim that circumcision reduces the risk for genital HPV infection"<ref>{{REFjournal
A meta-analysis performed by Dr. [[Robert Van Howe]] in 2006 found no significant association between circumcision status and HPV infection. "The medical literature does not support the claim that circumcision reduces the risk for genital HPV infection"<ref>{{REFjournal
  | last=Van Howe
  |last=Van Howe
  | first=Robert S.
  |first=Robert S.
  | coauthors=
  |author-link=Robert Van Howe
  | title=Human papillomavirus and circumcision: A meta-analysis
  |title=Human papillomavirus and circumcision: A meta-analysis
  | journal=Journal of Infection
  |journal=Journal of Infection
  | volume=54
  |volume=54
  | issue=5
  |issue=5
  | pages=490-496
  |pages=490-496
  | url=http://www.cirp.org/library/disease/cancer/vanhowe2006b/
  |url=http://www.cirp.org/library/disease/cancer/vanhowe2006b/
  | quote=
  |quote=
  | pubmedID=
  |pubmedID=
  | pubmedCID=
  |pubmedCID=
  | DOI=
  |DOI=
  | date=May 2007
  |date=May 2007
  | accessdate=2008-09-18
  |accessdate=2008-09-18
}}</ref>.
}}</ref>.


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"The percentage of circumcised men reporting a diagnosis of genital warts was significantly higher than uncircumcised men, 4.5% (95% CI, 3.6%–5.6%) versus 2.4% (95% CI, 1.5%–4.0%)".
"The percentage of circumcised men reporting a diagnosis of genital warts was significantly higher than uncircumcised men, 4.5% (95% CI, 3.6%–5.6%) versus 2.4% (95% CI, 1.5%–4.0%)".
<ref>{{REFjournal
<ref>{{REFjournal
  | last=Dinh
  |last=Dinh
  | first=T.H.
  |first=T.H.
  | coauthors=M. Sternberg, E.F. Dunne and L.E. Markowitz
  |first2=M.
  | title=Genital Warts Among 18- to 59-Year-Olds in the United States, National Health and Nutrition Examination Survey, 1999–2004
|last2=Sternberg
  | journal=Sexually Transmitted Diseases
|first3=E.F.
  | volume=35
|last3=Dunne
  | issue=4
|first4=L.E.
  | pages=357-360
|last4=Markowitz
  | url=http://journals.lww.com/stdjournal/Fulltext/2008/04000/Seroepidemiology_of_Human_Papillomavirus_Type_11.8.aspx
  |title=Genital Warts Among 18- to 59-Year-Olds in the United States, National Health and Nutrition Examination Survey, 1999–2004
  | quote=
  |journal=Sexually Transmitted Diseases
  | pubmedID=
  |volume=35
  | pubmedCID=
  |issue=4
  | DOI=
  |pages=357-360
  | date=April 2008
  |url=http://journals.lww.com/stdjournal/Fulltext/2008/04000/Seroepidemiology_of_Human_Papillomavirus_Type_11.8.aspx
  | accessdate=2011-03-05
  |quote=
  |pubmedID=
  |pubmedCID=
  |DOI=
  |date=April 2008
  |accessdate=2011-03-05
}}</ref>
}}</ref>


A 2011 study on University of Washington students found no correlation between circumcision and HPV.<ref>{{REFjournal
A 2011 study on University of Washington students found no correlation between circumcision and HPV.<ref>{{REFjournal
  | last=VanBuskirk
  |last=VanBuskirk
  | first=Kelley PhD
  |first=Kelley
  | coauthors=Winer, Rachel L. PhD; Hughes, James P. PhD; Feng, Qinghua PhD; Arima, Yuzo PhD; Lee, Shu-Kuang MS; Stern, Michael E. MN, ARNP; O'Reilly, Sandra F. BS; Koutsky, Laura A. PhD
  |last2=Winer
  | title=Circumcision and Acquisition of Human Papillomavirus Infection in Young Men
|first2=Rachel L.
  | journal=Sexually Transmitted Diseases
|last3=Hughes
  | volume=38
|first3=James P.
  | issue=12
|last4=Feng
  | pages=
|first4=Qinghua
  | url=
|last5=Arima
  | quote=rates of acquiring clinically relevant HPV types... did not differ significantly by circumcision status
|first5=Yuzo
  | pubmedID=
|last6=Lee
  | pubmedCID=
|first6=Shu-Kuang
  | DOI=10.1097/OLQ.0b013e31822e60cb
|last7=Stern
  | date=December 2011
|first7=Michael E.
  | accessdate=2011-09-02
|last8=O'Reilly
|first8=Sandra F.
|last9=Koutsky
|first9=Laura A.
  |title=Circumcision and Acquisition of Human Papillomavirus Infection in Young Men
  |journal=Sexually Transmitted Diseases
  |volume=38
  |issue=12
  |pages=
  |url=
  |quote=rates of acquiring clinically relevant HPV types... did not differ significantly by circumcision status
  |pubmedID=
  |pubmedCID=
  |DOI=10.1097/OLQ.0b013e31822e60cb
  |date=December 2011
  |accessdate=2011-09-02
}}</ref> This study tested for HPV at three sites: the scrotum/shaft skin, the glans, and in urine samples. The authors of this study found that in circumcised men, the scrotum/shaft skin contained was most often the site of HPV infection. The authors also note that many large-scale studies fail to test for HPV on scrotum/shaft skin.
}}</ref> This study tested for HPV at three sites: the scrotum/shaft skin, the glans, and in urine samples. The authors of this study found that in circumcised men, the scrotum/shaft skin contained was most often the site of HPV infection. The authors also note that many large-scale studies fail to test for HPV on scrotum/shaft skin.