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→Protective functions: Create new section.
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}}</ref> Frisch & Simonsen (2016) reported the incidence of meatal stenosis to be 3.7 times higher in circumcised boys.<ref name="frisch2016" />
==Immunological Functions==
Fleiss ''et al''. (1998) have listed numerous immunological functions of the foreskin that help to protect the human body against infection. The sub-preputial moisture contains cathepsin B, chymotrypsin, neutrophil elastase, cytokines, and lysozyme, which has the capacity to desttroy the cell walls of bacteria. The preputial muscles keep the tip of the foreskin closed to keep out pathogens.
==Sexual Functions==