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[[Image:Keratinization_intact_vs_circumcised.JPG |thumbnail|right|200px| The glans and mucosa of intact and circumcised human penises in adult males.]]
|DOI=
|date=2010-03-27
|accessdate=2020-06-07
}}</ref> Another study found that "no difference can be clearly visualized between the inner and outer foreskin."<!-- <ref>{{REFcontribution
| contribution=HIV-1 Interactions and Infection in Adult Male Foreskin Explant Cultures
}}</ref>--> Be that as it may, this hypothesis continues to be popular among researchers who advocate for circumcision as STD prevention.
Higher incidence of [[Circumcision and HIV|HIV infection]] is found in circumcised men who lack the immunological protection of the [[foreskin]] and its [[Langerhans cells]].<ref name="rosenberg2018">{{REFjournal |last=Rosenberg |first=Molly S. |author-link= |last2=Gómez-Olivé |first2=FX |author2-link= |last3=Ronr |first3=Julia K |author3-link= |last4=Kahn |first4=Kathleen |author4-link= |last5=Bärnighausen |first5=Till W |author5-link= |etal=no |title=Are circumcised men safer sex partners? Findings from the HAALSI cohort in rural South Africa |trans-title= |language= |journal=PLOS ONE |date=2018-08-01 |volume=13 |issue=8 |page=e0201445 |url=https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0201445 |quote= |pubmedID=30067842 |pubmedCID=6070310 |DOI= https://doi.org/10.1371/journal.pone.0201445 |accessdate=2019-10-20}}</ref>
==Treatment==
[[Foreskin restoration]] by non-surgical means has been found to reduce keratinization and to improve appearance and sensation. {{SEEALSO}} * [[Immunological and protective function of the foreskin]]
{{REF}}
[[Category:Physiology]]
[[Category:Penile disorders]]
[[Category:Foreskin anatomy]]
[[Category:From Intactipedia]]
[[Category:From IntactWiki]]
[[de:Keratinisierung]]