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Kigozi has been closely associated with the Rakai project to promote male circumcision as a prophylactic measure against HIV, HPV, and other diseases for many years. The Rakai Project produced one of the three deeply flawed RCTs. He has co-authored numerous papers on HIV and circumcision with [[Aaron Tobian]], [[Ronald H. Gray]] and , [[Maria Wawer]], and other authors. PubMed names Kigozi as an author of 189 papers, almost all of which promote male circumcision is some way. He is deeply immersed in the promotion of male circumcision.