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→The immunological function of the foreskin: Wikify "Langerhans cells".
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}}</ref> which is a very important non-antibody protein that generates immune response when in contact with specific agents. Plasma cells which increase in number in response to pathogens levels, secrete immunoglobulin.<ref name="flower1983"/>
It is also very important to note that [[Langerhans cells ]] that are present in the foreskin produce ''Langerin'', a substance that has been proven to kill human immunodeficency virus (HIV) on contact.<ref>{{REFjournal
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