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'''Lower clinical neurophysiological elicitability of the penilo-cavernosus reflex''' is classified as a late [[complication]] of [[circumcision]] by Iacob et al. (2021).<ref name="iacob2021">{{REFjournal
|last=Iacob
}}</ref>
The bulbocavernosus reflex has been found to be delayed or absent at a higher rate than the general population of [[intact]] men in diabetic men with complaints of erectile impotence, and men whose penises have been circumcised or , and in intact men who have permanent retraction of the [[foreskin]] behind the [[glans penis]].<ref name="podnar2012" />
Podnar cited previous research in explaining his findings. Among other works, Taylor et al. (1996) carried out a histological study of the foreskin which found large numbers of [[Meissner's corpuscles]] arranged in a [[ridged band]].<ref name="taylor1996">{{TaylorJR LockwoodAP TaylorAJ 1996}}</ref> and Sorrells et al. (2007) carried out a study of the fine-touch pressure thresholds on the human penis and found that the most sensitive areas are all on the foreskin.)<ref name="sorrells2007">{{Sorrells etal 2007}}</ref>
Men who have suffered the loss of their foreskin to [[amputation]] and men whose foreskin has been desensitized by permanent retraction evidently are unable to sense the stimulation necessary to trigger the penilo-cavernosus reflex..<ref name="podnar2012" />
|ref=<ref name="podnar2012" />
}}
Podnar's study highlights the importance of the sensory input from the nerves of the foreskin in the regulation of physiological functions through the autonomic nervous system.
{{SEEALSO}}
* [[Foreskin sensitivity]]
* [[Sexual effects of circumcision]]
{{REF}}