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|date=2012
|accessdate=2022-10-07
}}</ref> The preputial sac is lined with [[mucosa]] as is appropriate for an internal location. Moistness is maintained by [[transudation]].
Moistness is maintained by [[Smegmatransudation]]. Parkash et al. (1973) reported that epithelial debris accumulates in the preputial sac and forms [[smegma]].<ref name="parkash1873">{{REFjournal |last=Parkash |first= |init=S |author-link= |last2=Jayakumar |first2= |init2=S |author2-link= |last3=Subramanyan |first3= |init3=K |author3-link= |last4=Chaudhuri |first4= |init4=S |author4-link= |last5= |etal=no |title=Human subpreputial collection: its nature and formation. |trans-title= |language= |journal=J. Urol. |location= |date=1973-08 |season= |volume=110 |issue=2 |article= |page= |pages=111-2 |url=http://www.cirp.org/library/anatomy/parkash/ |archived= |quote= |pubmedID=4722614 |pubmedCID= |DOI=10.1016/s0022-5347(17)60164-2 |accessdate=2022-10-07}}</ref>, a natural, normal, benign, healthy, and beneficial product of the body, which will collect in the preputial sac.