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Born in San Mateo, California, and professionally trained as a registered nurse, Milos started campaigning against [[circumcision]] with nurses and parents in 1979. The spark for her activism was an experience at a newborn nursery, where she had been instructed to attend a circumcision of an infant boy.<ref>Marilyn Fayre Milos, "Infant Circumcision: What I Wish I Had Known," ''Truth Seeker'', vol. 1, no. 3 (July–August 1989), p. 3.</ref> In 1985, when she was working as a nurse on an obstetrical service, Milos was forced to resign by the hospital administration for discussing circumcision with patients. In the same year, she founded [[NOCIRC]].<ref name="Glick">[[Leonard B. Glick]], ''Marked in Your Flesh: Circumcision from Ancient Judea to Modern America'' (New York: Oxford University Press, 2005), p. 4.</ref>