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Advanced Tissue Sciences is a corporation based in La Jolla, CA. They are the makers of [[Dermagraft-TC]], which is an artifical skin created from harvested foreskins from infant circumcision.<ref name='Advanced Biohealing, 2010'>{{REFwebQuote
'''Advanced Tissue Sciences''' is a corporation based in La Jolla, {{USSC|CA}}. They are the makers of [[Dermagraft-TC]], which is an artifical [[skin]] created from harvested [[foreskin]]s from infant [[circumcision]].<ref name='Advanced Biohealing, 2010'>{{REFweb
  | quote=Dermagraft is manufactured from human fibroblast cells derived from newborn foreskin tissue.
  |quote=Dermagraft is manufactured from human fibroblast cells derived from newborn foreskin tissue.
  | last=
  |last=
  | first=
  |first=
  | publisher=Advanced Biohealing, Inc.
  |publisher=Advanced Biohealing, Inc.
  | year=
  |date=
  | urltitle=Dermagraft-TC: Overview
  |title=Dermagraft-TC: Overview
  | url=http://www.dermagraft.com/about/overview/
  |url=http://www.dermagraft.com/about/overview/
  | accessdate=2011-03-06
  |accessdate=2011-03-06
}}</ref> They are also the makers of [[NouriCel]], another product made from harvested foreskins,<ref name='Acroposthion 2011'>{{ REFwebQuote
}}</ref> They are also the makers of [[NouriCel]], another product made from harvested foreskins,<ref name='Acroposthion 2011'>{{REFweb
  | quote=TNS contains... NouriCel-MD which is... a combination of Natural Growth Factors, matrix proteins, and soluble collagen. Human Growth Factors extracted from cultured cells of foreskin...
  |quote=TNS contains... NouriCel-MD which is... a combination of Natural Growth Factors, matrix proteins, and soluble collagen. Human Growth Factors extracted from cultured cells of foreskin...
  | last=
  |last=
  | first=
  |first=
  | publisher=Acroposthion.com
  |publisher=Acroposthion.com
  | year=
  |date=
  | urltitle=The Foreskin Mafia
  |title=The Foreskin Mafia
  | url=http://www.acroposthion.com/acroposthion_019.htm
  |url=http://www.acroposthion.com/acroposthion_019.htm
  | accessdate=2011-03-06
  |accessdate=2011-03-06
}}</ref> and one of the main ingredients of [[SkinMedica]]'s [[TNS Recovery Complex]] product.<ref name='SkinMedica 2011'>{{REFwebQuote
}}</ref> and one of the main ingredients of [[SkinMedica]]'s [[TNS Recovery Complex]] product.<ref name='SkinMedica 2011'>{{REFweb
  | quote=TNS Recovery Complex is the only product containing a professional concentration of NouriCel®, a new cosmetic ingredient from leading tissue-engineering company Advanced Tissue Sciences.
  |quote=TNS Recovery Complex is the only product containing a professional concentration of NouriCel®, a new cosmetic ingredient from leading tissue-engineering company Advanced Tissue Sciences.
  | last=
  |last=
  | first=
  |first=
  | publisher=SkinMedica
  |publisher=SkinMedica
  | year=2002-02-12
  |date=2002-02-12
  | urltitle=SkinMedica Introduces TNS Recovery Complex
  |title=SkinMedica Introduces TNS Recovery Complex
  | url=http://www.corporate.skinmedica.com/press/2002/skinmedica-launches-tns-recovery-complex
  |url=http://www.corporate.skinmedica.com/press/2002/skinmedica-launches-tns-recovery-complex
  | accessdate=2011-03-06
  |accessdate=2011-03-06
}}</ref>
}}</ref>


== Earnings ==
== Earnings ==


Dermagraft-TC is FDA approved,<ref>{{REFwebQuote
Dermagraft-TC is FDA approved,<ref>{{REFweb
  | quote=Dermagraft-TC is the first human, fibroblast-derived temporary skin substitute for the treatment of partial-thickness burns that has been approved for marketing by the FDA.
  |quote=Dermagraft-TC is the first human, fibroblast-derived temporary [[skin]] substitute for the treatment of partial-thickness burns that has been approved for marketing by the FDA.
  | last=
  |last=
  | first=
  |first=
  | publisher=MediLexicon International Ltd
  |publisher=MediLexicon International Ltd
  | year=2011
  |date=2011
  | urltitle=Dermagraft-TC: General Information: Advanced Tissue Sciences
  |title=Dermagraft-TC: General Information: Advanced Tissue Sciences
  | url=http://www.medilexicon.com/drugs/dermagraft-tc.php#GeneralInformation
  |url=http://www.medilexicon.com/drugs/dermagraft-tc.php#GeneralInformation
  | accessdate=2011-05-07
  |accessdate=2011-05-07
}}</ref><ref>{{REFwebQuote
}}</ref><ref>{{REFweb
  | quote=the Food and Drug Administration has approved Dermagraft-TC
  |quote=the Food and Drug Administration has approved Dermagraft-TC
  | last=
  |last=
  | first=
  |first=
  | publisher=HighBeam Research
  |publisher=HighBeam Research
  | year=1997-03-28
  |date=1997-03-28
  | urltitle= Transplant News: Advanced Tissue Sciences' temporary wound covering Dermagraft-TC approved for marketing by FDA
  |title= Transplant News: Advanced Tissue Sciences' temporary wound covering Dermagraft-TC approved for marketing by FDA
  | url=http://www.highbeam.com/doc/1G1-47248437.html
  |url=http://www.highbeam.com/doc/1G1-47248437.html
  | accessdate=2011-05-07
  |accessdate=2011-05-07
}}</ref> and it sells for about $3,000 per square foot and one foreskin contains enough genetic material to grow 250,000 square feet of skin.<ref>Circumcision. Daecher M. Icon 1998;2(2):70-3.</ref>
}}</ref> and it sells for about $3,000 per square foot and one foreskin contains enough genetic material to grow 250,000 square feet of [[skin]].<ref>Circumcision. Daecher M. Icon 1998;2(2):70-3.</ref>


Advanced Tissue Sciences has sold about $1 million worth of cultured dermis to Proctor & Gamble, Helene Curtis, and other such businesses for pre-market testing. Advanced Tissue Science's foreskin-derived merchandise held a $32 million stock offering in the beginning of 1992.<ref>{{REFbook
Advanced Tissue Sciences has sold about $1 million worth of cultured dermis to Proctor & Gamble, Helene Curtis, and other such businesses for pre-market testing. Advanced Tissue Science's foreskin-derived merchandise held a $32 million stock offering in the beginning of 1992.<ref>{{REFbook
  | last=Pitta
  |last=Pitta
  | first=Julie
  |first=Julie
  | year=10 May 1993
  |init=J
  | title=Biosynthetics
|date=1993-05-10
  | url=
  |title=Biosynthetics
  | editor=
  |url=
  | edition=
  |editor=
  | volume=
  |edition=
  | chapter=
  |volume=
  | pages=170-171
  |chapter=
  | location=
  |pages=170-1
  | publisher=Forbes  
  |location=
  | isbn=
  |publisher=Forbes  
  | note=The 32-page Advanced Tissue Sciences, Inc. 1997 Annual Report refers to "fibroblasts" but does not contain the word "foreskin."
  |isbn=
| accessdate=
|accessdate=
  |note=The 32-page Advanced Tissue Sciences, Inc. 1997 Annual Report refers to "fibroblasts" but does not contain the word "foreskin."
}}</ref>
}}</ref>


In 1996 alone, Advanced Tissue Sciences could boast of a healthy $663.9 million market capitalization performance.<ref>Biotech's Big Discovery. Hall CT. San Francisco Chronicle. October 25, 1996: E1, E4.</ref>
In 1996 alone, Advanced Tissue Sciences could boast of a healthy $663.9 million market capitalization performance.<ref>{{REFjournal
|title=Biotech's Big Discovery
|last=Hall
|init=CT
|journal=San Francisco Chronicle
|date=1996-10-25
|pages=E1+E4
}}</ref>
 
{{SEEALSO}}
* [[Gail K. Naughton]]


{{REF}}
{{REF}}
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