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[[Amputation]] Debridement of the dead tissue appears to be the most common treatment for gangrene.<ref>{{REFweb |url=https://my.clevelandclinic.org/health/diseases/21070-gangrene |title=Gangrene |last=Anonymous |first= |init= |author-link= |publisher=Cleveland Clinic |date= |accessdate=2025-12-13}}</ref>
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Gangrene of the [[foreskin]] is a legitimate [[medical indication]] for [[circumcision]] of the foreskin.