Meissner's corpuscles

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Meissner's corpuscles are a type of mechanoreceptor discovered by anatomist Georg Meissner (1829 – 1905) and Rudolf Wagner.[1][2]

They are a type of nerve ending in the skin that is responsible for sensitivity to light touch. In particular, they have their highest sensitivity (lowest threshold) when sensing vibrations between 10 and 50 hertz. They are rapidly adaptive receptors. They are most concentrated in thick hairless skin, especially at the finger pads.

Description

Meissner's corpuscles are encapsulated unmyelinated nerve endings, surrounded by Schwann cells.[3] The encapsulation consists of flattened supportive cells arranged as horizontal lamellae surrounded by a connective tissue capsule.

Location

They are distributed on various areas of the skin, but concentrated in areas especially sensitive to light touch, such as the fingers and lips. More specifically, they are primarily located in glabrous (non-hair bearing) skin just beneath the epidermis within the dermal papillae.

Taylor, Lockwood, & Taylor (1996) carried out a gross and histological examination of the prepuce. They reported that numerous Meissner's corpuscles are found in a ridged band area where the Meissner corpuscles are found near the tops of the ridges.[4]


References

  1. REFweb Georg Meissner. Retrieved 21 October 2020.
  2. REFjournal Paré, Michel, Elde, Robert, Mazurkiewicz, Joseph E., Smith, Allan M., Rice, Frank L.. The Meissner Corpuscle Revised: A Multiafferented Mechanoreceptor with Nociceptor Immunochemical Properties. J Neurosci. 15 September 2001; 21(18): 7236-46. PMID. PMC. DOI. Retrieved 21 October 2020.
  3. REFweb (4 April 2011). Meissner’s Corpuscles. Retrieved 25 October 2020.
  4. REFjournal Taylor, J.R., Lockwood, A.P., Taylor, A.J.. The prepuce: specialized mucosa of the penis and its loss to circumcision. Brit J Urol. 1996; 77: 291-5. PMID. DOI. Retrieved 25 October 2020.