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===Foreskin in infancy and childhood===
Baby boys are born with the foreskin fused with the glans penis by a [[synechia| synechial membrane]]. The tip of the foreskin is usually too narrow to allow [[retraction of the foreskin]].The preputial cavity is closed and cannot be infected.<ref name="fleiss-hodges-vanhowe1998"/>
Thorvaldsen & Meyhoff (2005) conducted a survey of 4,000 boys in Denmark. They report that the mean age of first foreskin retraction is 10.4 years in Denmark.<ref name="Thorvaldsen-meyhoff2005">{{REFjournal
===Foreskin in adulthood===
The foreskin (also known as the prepuce) is the double-layered fold of smooth muscle tissue, blood vessels, neurons, skin, and mucous membrane part of the penis that covers and protects the glans penis and the urinary meatus.<ref name="cold-taylor1999"/> The adult foreskin comprises more than fifty percent of the epithelium of the penismeasures about 3 inches by 5 inches or 15 square inches.<ref name="taylor1996">{{REFjournal
|last=Taylor
|first=J.R.
|last3=Van Howe
|first3=R.S.
|author3-link=Robert S. Van Howe
|title=Immunological functions of the human prepuce
|journal=Sex Trans Infect