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Adhanom Ghebreyesus was born in Ethiopia in 1965. <ref name="CV">{{REFweb |url=https://www.who.int/dg/election/cv-tedros-en.pdf |title=Curriculum Vitae |last= |first= |accessdate=2021-11-25}}</ref> In 1986, he received a Bachelor of Science degree in biology from the [https://www.alluniversity.info/eritrea/university-of-asmara/ University of Asmara]. <ref name="CV" /> In 1986, after his first degree, he joined the [https://www.ethiopia.gov.et/ministries/ministry-of-health/ Ethiopian Ministry of Health] as a junior public health expert.

He studied at the [https://www.lshtm.ac.uk/ London School of Hygiene & Tropical Medicine] and was awarded a Master of Science degree in immunology of infectious diseases from the [https://london.ac.uk/ University of London] in 1992.<ref name="CV" />