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}}</ref> They also occur in the papillary dermis, particularly around blood vessels,<ref name=Wheaters /> as well as in the oral [[mucosa]], [[foreskin]], and [[vagina]].<ref name=pmid7558138 /> They can be found in other tissues, such as lymph nodes, particularly in association with the condition Langerhans cell histiocytosis (LCH).

Hussain & Lehner (2005) observed Langerhans cells have been observed in foreskin, vaginal, and oral [[mucosa ]] of humans; the lower concentrations in oral [[mucosa ]] suggest that it is not a likely source of [[HIV]] infection relative to foreskin and vaginal [[mucosa]].<ref name="pmid7558138">{{REFjournal