Langerhans cells
Langerhans cells are dendritic cells (antigen-presenting immune cells) of the skin and mucosa, and contain large granules called Birbeck granules. They are present in all layers of the epidermis, but are most prominent in the stratum spinosum.[2] They also occur in the papillary dermis, particularly around blood vessels,[2] as well as in the oral mucosa, foreskin, and vagina.[3] They can be found in other tissues, such as lymph nodes, particularly in association with the condition Langerhans cell histiocytosis (LCH).
History
The Langerhans cell is named after Paul Langerhans, a German physician and anatomist, who discovered the cells at the age of 21 while he was a medical student.[4] Because of their dendritic nature, he mistakenly identified the cells as part of the nervous system.[5]
Function
In skin infections, the local Langerhans cells take up and process microbial antigens to become fully functional antigen-presenting cells.
Generally, dendritic cells in biological tissue are active in the capture, uptake and processing of antigens. Once dendritic cells arrive in secondary lymphoid tissue, however, they lose these properties while gaining the capacity to interact with naive T-cells.
Langerhans cells derive from the cellular differentiation of monocytes with the marker "Gr-1" (also known as "Ly-6G/Ly-6C"). This differentiation requires stimulation by colony stimulating factor (CSF)-1.[6] They are similar in morphology and function to macrophages.
Langerin is a protein found in Langerhans cells,[7] and other types of dendritic cells.[8]
Clinical significance
LCH
In the rare disease Langerhans cell histiocytosis (LCH), an excess of these cells is produced. This can cause damage to skin, bone and other organs.
HIV
Former hypothesis
Kawamura et al. (2005) suggested Langerhans cells may be initial cellular targets in the sexual transmission of HIV,[9] and as a target, reservoir, and vector of dissemination.[10]
Hussain & Lehner (2005) observed Langerhans cells have been observed in foreskin, vaginal, and oral mucosa of humans; the lower concentrations in oral mucosa suggest that it is not a likely source of HIV infection relative to foreskin and vaginal mucosa.[3]
Present view
On 4 March 2007 the online Nature Medicine magazine published the letter "Langerin is a natural barrier to HIV-1 transmission by Langerhans cells."[11] One of the authors of the study, Teunis Geijtenbeek, said that "Langerin is able to scavenge viruses from the surrounding environment, thereby preventing infection" and "since generally all tissues on the outside of our bodies have Langerhans cells, we think that the human body is equipped with an antiviral defense mechanism, destroying incoming viruses."[12]
Population-based studies
September 2021 saw the publication of two huge population studies on the relationship of circumcision and HIV infection:
- Mayan et al. (2021) carried out a massive empirical study of the male population of the province of Ontario, Canada (569,950 males), of whom 203,588 (35.7%) were circumcised between 1991 and 2017. The study concluded that circumcision status is not related to risk of HIV infection.[13]
- Morten Frisch & Jacob Simonsen (2021) carried out a large scale empirical population study in Denmark of 855,654 males regarding the alleged value of male circumcision in preventing HIV and other sexually transmitted infections in men. They found that circumcised men have a higher rate of STI and HIV infection overall than intact men.[14]
No association between lack of circumcision and risk of HIV infection was found by either study. There now is credible evidence that the massive, expensive African circumcision programs have not been effective in preventing HIV infection.
Two African surveys
The previously reported studies were from developed Western nations. Now we have information from Sub_Saharan Africa.
French scientist Michel Garenne, Ph.D. has published two reports in 2022 comparing the incidence of HIV infection in circumcised and intact men.
In his first report, Garenne presented the findings from a study in Lesotho, the enclave in South Africa. He reported:
In couple studies, the effect of circumcision and VMMC on HIV was not significant, with similar transmission from female to male and male to female. The study questions the amount of effort and money spent on VMMC in Lesotho.[15]
In his second report, Garenne (2022) presented information from six Sub-Saharan African nations (Eswatini, Lesotho, Malawi, Namibia, Zambia, Zimbabwe). He reported:
"Results matched earlier observations made in South Africa that circumcised and intact men had similar levels of HIV infection."[16]
See also
References
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Quote: |}} - ↑ REFjournal {{#if:Ginhoux|{{#if:|{{#if:F|[[{{{author-link}}}|Ginhoux F]]|[[{{{author-link}}}|Ginhoux{{#if:Florent|, Florent|}}]]}}|{{#if:F|Ginhoux F|Ginhoux{{#if:Florent|, Florent|}}|}}|}}|}}{{#if:Tacke|{{#if:|{{#if:F|, [[{{{author2-link}}}|Tacke F]]|, [[{{{author2-link}}}|Tacke{{#if:Frank|, Frank|}}]]}}|{{#if:F|, Tacke F|, Tacke{{#if:Frank|, Frank|}}|}}|}}|}}{{#if:Angeli|{{#if:|{{#if:V|, [[{{{author3-link}}}|Angeli V]]|, [[{{{author3-link}}}|Angeli{{#if:Veronique|, Veronique|}}]]}}|{{#if:V|, Angeli V|, Angeli{{#if:Veronique|, Veronique|}}|}}|}}|}}{{#if:Bogunovic|{{#if:|{{#if:M|, [[{{{author4-link}}}|Bogunovic M]]|, [[{{{author4-link}}}|Bogunovic{{#if:Milena|, Milena|}}]]}}|{{#if:M|, Bogunovic M|, Bogunovic{{#if:Milena|, Milena|}}|}}|}}|}}{{#if:Loubeau|{{#if:|{{#if:M|, [[{{{author5-link}}}|Loubeau M]]|, [[{{{author5-link}}}|Loubeau{{#if:Martine|, Martine|}}]]}}|{{#if:M|, Loubeau M|, Loubeau{{#if:Martine|, Martine|}}|}}|}}|}}{{#if:Dai|{{#if:|{{#if:XM|, [[{{{author6-link}}}|Dai XM]]|, [[{{{author6-link}}}|Dai{{#if:Xu-Ming|, Xu-Ming|}}]]}}|{{#if:XM|, Dai XM|, Dai{{#if:Xu-Ming|, Xu-Ming|}}|}}|}}|}}{{#if:Stanley|{{#if:|{{#if:ER|, [[{{{author7-link}}}|Stanley ER]]|, [[{{{author7-link}}}|Stanley{{#if:E. Richard|, E. Richard|}}]]}}|{{#if:ER|, Stanley ER|, Stanley{{#if:E. Richard|, E. Richard|}}|}}|}}|}}{{#if:Randolph|{{#if:|{{#if:GJ|, [[{{{author8-link}}}|Randolph GJ]]|, [[{{{author8-link}}}|Randolph{{#if:Gwendalyn J.|, Gwendalyn J.|}}]]}}|{{#if:GJ|, Randolph GJ|, Randolph{{#if:Gwendalyn J.|, Gwendalyn J.|}}|}}|}}|}}{{#if:Merad|{{#if:|{{#if:M|, [[{{{author9-link}}}|Merad M]]|, [[{{{author9-link}}}|Merad{{#if:Miriam|, Miriam|}}]]}}|{{#if:M|, Merad M|, Merad{{#if:Miriam|, Miriam|}}|}}|}}|}}{{#if:|; with {{{coauthors}}} [deprecated REFjournal parameter used: <coauthors> - please use <last2>, etc.]|}}{{#ifeq:|yes|, et al.|{{#if:Ginhoux|.|}}}}{{#if:| ({{{publisher}}})|}} {{#if:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727824/%7CLangerhans cells arise from monocytes in vivo{{#if:| PDF|}}{{#ifeq:|yes| (archive URL)|}}|Langerhans cells arise from monocytes in vivo}}{{#if:| [{{{trans-title}}}]{{#if:| ({{{language}}})|}}|}}{{#if:Nature Immunology|. Nature Immunology{{#if:| ({{{location}}})}}.|}}{{#if:2016-01-26| {{#switch:{{#invoke:String|len|s=2016-01-26}}
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|3 |4 |5 = {{#time:Y|2016-01-26 }}
|6 |7 |8 = {{#time:F Y|2016-01-26 }}
|9 |10 = {{#time:j F Y|2016-01-26 }}
|#default = error
}}{{#if:| ({{{season}}})|}}; | }}{{#if:7| 7|}}{{#if:3|(3)|}}{{#if: 265-273|{{#if:|: [{{{article}}}]|}}{{#if:|: {{{page}}}|}}{{#if:265-273|: 265-273|}}.|}}{{#if:16444257| PMID.|}}{{#if:| PMC.|}}{{#if:10.1038/ni1307| DOI.|}}{{#if:| DOI.|}}{{#if:2019-10-20| Retrieved {{#switch:{{#invoke:String|len|s=2019-10-20}}
|0 |1 |2 =
|3 |4 |5 = {{#time:Y|2019-10-20 }}
|6 |7 |8 = {{#time:F Y|2019-10-20 }}
|9 |10 = {{#time:j F Y|2019-10-20 }}
|#default = error
}}.|}}{{#if:|
Quote: |}} - ↑ REFjournal {{#if:Valladeau|{{#if:|{{#if:J|[[{{{author-link}}}|Valladeau J]]|[[{{{author-link}}}|Valladeau{{#if:Jenny|, Jenny|}}]]}}|{{#if:J|Valladeau J|Valladeau{{#if:Jenny|, Jenny|}}|}}|}}|}}{{#if:Dezutter-Dambuyant|{{#if:|{{#if:C|, [[{{{author2-link}}}|Dezutter-Dambuyant C]]|, [[{{{author2-link}}}|Dezutter-Dambuyant{{#if:Colette|, Colette|}}]]}}|{{#if:C|, Dezutter-Dambuyant C|, Dezutter-Dambuyant{{#if:Colette|, Colette|}}|}}|}}|}}{{#if:Saeland|{{#if:|{{#if:S|, [[{{{author3-link}}}|Saeland S]]|, [[{{{author3-link}}}|Saeland{{#if:Sem|, Sem|}}]]}}|{{#if:S|, Saeland S|, Saeland{{#if:Sem|, Sem|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author4-link}}}|{{{last4}}} {{{init4}}}]]|, [[{{{author4-link}}}|{{{last4}}}{{#if:|, {{{first4}}}|}}]]}}|{{#if:|, {{{last4}}} {{{init4}}}|, {{{last4}}}{{#if:|, {{{first4}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author5-link}}}|{{{last5}}} {{{init5}}}]]|, [[{{{author5-link}}}|{{{last5}}}{{#if:|, {{{first5}}}|}}]]}}|{{#if:|, {{{last5}}} {{{init5}}}|, {{{last5}}}{{#if:|, {{{first5}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author6-link}}}|{{{last6}}} {{{init6}}}]]|, [[{{{author6-link}}}|{{{last6}}}{{#if:|, {{{first6}}}|}}]]}}|{{#if:|, {{{last6}}} {{{init6}}}|, {{{last6}}}{{#if:|, {{{first6}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author7-link}}}|{{{last7}}} {{{init7}}}]]|, [[{{{author7-link}}}|{{{last7}}}{{#if:|, {{{first7}}}|}}]]}}|{{#if:|, {{{last7}}} {{{init7}}}|, {{{last7}}}{{#if:|, {{{first7}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author8-link}}}|{{{last8}}} {{{init8}}}]]|, [[{{{author8-link}}}|{{{last8}}}{{#if:|, {{{first8}}}|}}]]}}|{{#if:|, {{{last8}}} {{{init8}}}|, {{{last8}}}{{#if:|, {{{first8}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author9-link}}}|{{{last9}}} {{{init9}}}]]|, [[{{{author9-link}}}|{{{last9}}}{{#if:|, {{{first9}}}|}}]]}}|{{#if:|, {{{last9}}} {{{init9}}}|, {{{last9}}}{{#if:|, {{{first9}}}|}}|}}|}}|}}{{#if:|; with {{{coauthors}}} [deprecated REFjournal parameter used: <coauthors> - please use <last2>, etc.]|}}{{#ifeq:|yes|, et al.|{{#if:Valladeau|.|}}}}{{#if:| ({{{publisher}}})|}} {{#if:https://link.springer.com/article/10.1385/IR:28:2:93%7CLangerin/CD207 Sheds Light on Formation of Birbeck Granules and Their Possible Function in Langerhans Cells{{#if:| PDF|}}{{#ifeq:|yes| (archive URL)|}}|Langerin/CD207 Sheds Light on Formation of Birbeck Granules and Their Possible Function in Langerhans Cells}}{{#if:| [{{{trans-title}}}]{{#if:| ({{{language}}})|}}|}}{{#if:Immunologic Research|. Immunologic Research{{#if:| ({{{location}}})}}.|}}{{#if:2003-10| {{#switch:{{#invoke:String|len|s=2003-10}}
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|3 |4 |5 = {{#time:Y|2003-10 }}
|6 |7 |8 = {{#time:F Y|2003-10 }}
|9 |10 = {{#time:j F Y|2003-10 }}
|#default = error
}}{{#if:| ({{{season}}})|}}; | }}{{#if:28| 28|}}{{#if:2|(2)|}}{{#if: 93-107|{{#if:|: [{{{article}}}]|}}{{#if:|: {{{page}}}|}}{{#if:93-107|: 93-107|}}.|}}{{#if:14610287| PMID.|}}{{#if:| PMC.|}}{{#if:10.1385/IR:28:2:93| DOI.|}}{{#if:| DOI.|}}{{#if:2010-10-20| Retrieved {{#switch:{{#invoke:String|len|s=2010-10-20}}
|0 |1 |2 =
|3 |4 |5 = {{#time:Y|2010-10-20 }}
|6 |7 |8 = {{#time:F Y|2010-10-20 }}
|9 |10 = {{#time:j F Y|2010-10-20 }}
|#default = error
}}.|}}{{#if:|
Quote: |}} - ↑ REFjournal {{#if:Poulin|{{#if:|{{#if:LF|[[{{{author-link}}}|Poulin LF]]|[[{{{author-link}}}|Poulin{{#if:Lionel Franz|, Lionel Franz|}}]]}}|{{#if:LF|Poulin LF|Poulin{{#if:Lionel Franz|, Lionel Franz|}}|}}|}}|}}{{#if:Henri|{{#if:|{{#if:S|, [[{{{author2-link}}}|Henri S]]|, [[{{{author2-link}}}|Henri{{#if:Sandrine|, Sandrine|}}]]}}|{{#if:S|, Henri S|, Henri{{#if:Sandrine|, Sandrine|}}|}}|}}|}}{{#if:de Bovis|{{#if:|{{#if:B|, [[{{{author3-link}}}|de Bovis B]]|, [[{{{author3-link}}}|de Bovis{{#if:Béatrice|, Béatrice|}}]]}}|{{#if:B|, de Bovis B|, de Bovis{{#if:Béatrice|, Béatrice|}}|}}|}}|}}{{#if:Devilard|{{#if:|{{#if:E|, [[{{{author4-link}}}|Devilard E]]|, [[{{{author4-link}}}|Devilard{{#if:Elisabeth|, Elisabeth|}}]]}}|{{#if:E|, Devilard E|, Devilard{{#if:Elisabeth|, Elisabeth|}}|}}|}}|}}{{#if:Kissenpfennig|{{#if:|{{#if:A|, [[{{{author5-link}}}|Kissenpfennig A]]|, [[{{{author5-link}}}|Kissenpfennig{{#if:Adrien|, Adrien|}}]]}}|{{#if:A|, Kissenpfennig A|, Kissenpfennig{{#if:Adrien|, Adrien|}}|}}|}}|}}{{#if:Malissen|{{#if:|{{#if:B|, [[{{{author6-link}}}|Malissen B]]|, [[{{{author6-link}}}|Malissen{{#if:Bernard|, Bernard|}}]]}}|{{#if:B|, Malissen B|, Malissen{{#if:Bernard|, Bernard|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author7-link}}}|{{{last7}}} {{{init7}}}]]|, [[{{{author7-link}}}|{{{last7}}}{{#if:|, {{{first7}}}|}}]]}}|{{#if:|, {{{last7}}} {{{init7}}}|, {{{last7}}}{{#if:|, {{{first7}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author8-link}}}|{{{last8}}} {{{init8}}}]]|, [[{{{author8-link}}}|{{{last8}}}{{#if:|, {{{first8}}}|}}]]}}|{{#if:|, {{{last8}}} {{{init8}}}|, {{{last8}}}{{#if:|, {{{first8}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author9-link}}}|{{{last9}}} {{{init9}}}]]|, [[{{{author9-link}}}|{{{last9}}}{{#if:|, {{{first9}}}|}}]]}}|{{#if:|, {{{last9}}} {{{init9}}}|, {{{last9}}}{{#if:|, {{{first9}}}|}}|}}|}}|}}{{#if:|; with {{{coauthors}}} [deprecated REFjournal parameter used: <coauthors> - please use <last2>, etc.]|}}{{#ifeq:|yes|, et al.|{{#if:Poulin|.|}}}}{{#if:| ({{{publisher}}})|}} {{#if:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150992/%7CThe dermis contains langerin+ dendritic cells that develop and function independently of epidermal Langerhans cells{{#if:| PDF|}}{{#ifeq:|yes| (archive URL)|}}|The dermis contains langerin+ dendritic cells that develop and function independently of epidermal Langerhans cells}}{{#if:| [{{{trans-title}}}]{{#if:| ({{{language}}})|}}|}}{{#if:Journal of Experimental Medicine|. Journal of Experimental Medicine{{#if:| ({{{location}}})}}.|}}{{#if:2007-12-24| {{#switch:{{#invoke:String|len|s=2007-12-24}}
|0 |1 |2 =
|3 |4 |5 = {{#time:Y|2007-12-24 }}
|6 |7 |8 = {{#time:F Y|2007-12-24 }}
|9 |10 = {{#time:j F Y|2007-12-24 }}
|#default = error
}}{{#if:| ({{{season}}})|}}; | }}{{#if:204| 204|}}{{#if:13|(13)|}}{{#if: 3119-3131|{{#if:|: [{{{article}}}]|}}{{#if:|: {{{page}}}|}}{{#if:3119-3131|: 3119-3131|}}.|}}{{#if:18086861| PMID.|}}{{#if:2150992| PMC.|}}{{#if:10.1084/jem.20071724| DOI.|}}{{#if:| DOI.|}}{{#if:2019-10-20| Retrieved {{#switch:{{#invoke:String|len|s=2019-10-20}}
|0 |1 |2 =
|3 |4 |5 = {{#time:Y|2019-10-20 }}
|6 |7 |8 = {{#time:F Y|2019-10-20 }}
|9 |10 = {{#time:j F Y|2019-10-20 }}
|#default = error
}}.|}}{{#if:|
Quote: |}} - ↑ REFjournal {{#if:Kawamura|{{#if:|{{#if:T|[[{{{author-link}}}|Kawamura T]]|[[{{{author-link}}}|Kawamura{{#if:Tatsuyoshi|, Tatsuyoshi|}}]]}}|{{#if:T|Kawamura T|Kawamura{{#if:Tatsuyoshi|, Tatsuyoshi|}}|}}|}}|}}{{#if:Kurtz|{{#if:|{{#if:SE|, [[{{{author2-link}}}|Kurtz SE]]|, [[{{{author2-link}}}|Kurtz{{#if:Stephen E.|, Stephen E.|}}]]}}|{{#if:SE|, Kurtz SE|, Kurtz{{#if:Stephen E.|, Stephen E.|}}|}}|}}|}}{{#if:Blauvelt|{{#if:|{{#if:A|, [[{{{author3-link}}}|Blauvelt A]]|, [[{{{author3-link}}}|Blauvelt{{#if:Andrew|, Andrew|}}]]}}|{{#if:A|, Blauvelt A|, Blauvelt{{#if:Andrew|, Andrew|}}|}}|}}|}}{{#if:Shimada|{{#if:|{{#if:S|, [[{{{author4-link}}}|Shimada S]]|, [[{{{author4-link}}}|Shimada{{#if:Shinji|, Shinji|}}]]}}|{{#if:S|, Shimada S|, Shimada{{#if:Shinji|, Shinji|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author5-link}}}|{{{last5}}} {{{init5}}}]]|, [[{{{author5-link}}}|{{{last5}}}{{#if:|, {{{first5}}}|}}]]}}|{{#if:|, {{{last5}}} {{{init5}}}|, {{{last5}}}{{#if:|, {{{first5}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author6-link}}}|{{{last6}}} {{{init6}}}]]|, [[{{{author6-link}}}|{{{last6}}}{{#if:|, {{{first6}}}|}}]]}}|{{#if:|, {{{last6}}} {{{init6}}}|, {{{last6}}}{{#if:|, {{{first6}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author7-link}}}|{{{last7}}} {{{init7}}}]]|, [[{{{author7-link}}}|{{{last7}}}{{#if:|, {{{first7}}}|}}]]}}|{{#if:|, {{{last7}}} {{{init7}}}|, {{{last7}}}{{#if:|, {{{first7}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author8-link}}}|{{{last8}}} {{{init8}}}]]|, [[{{{author8-link}}}|{{{last8}}}{{#if:|, {{{first8}}}|}}]]}}|{{#if:|, {{{last8}}} {{{init8}}}|, {{{last8}}}{{#if:|, {{{first8}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author9-link}}}|{{{last9}}} {{{init9}}}]]|, [[{{{author9-link}}}|{{{last9}}}{{#if:|, {{{first9}}}|}}]]}}|{{#if:|, {{{last9}}} {{{init9}}}|, {{{last9}}}{{#if:|, {{{first9}}}|}}|}}|}}|}}{{#if:|; with {{{coauthors}}} [deprecated REFjournal parameter used: <coauthors> - please use <last2>, etc.]|}}{{#ifeq:|yes|, et al.|{{#if:Kawamura|.|}}}}{{#if:| ({{{publisher}}})|}} {{#if:https://www.sciencedirect.com/science/article/pii/S0923181105002586%7CThe role of Langerhans cells in the sexual transmission of HIV{{#if:| PDF|}}{{#ifeq:|yes| (archive URL)|}}|The role of Langerhans cells in the sexual transmission of HIV}}{{#if:| [{{{trans-title}}}]{{#if:| ({{{language}}})|}}|}}{{#if:Journal of Dermatological Science|. Journal of Dermatological Science{{#if:| ({{{location}}})}}.|}}{{#if:2005-12| {{#switch:{{#invoke:String|len|s=2005-12}}
|0 |1 |2 =
|3 |4 |5 = {{#time:Y|2005-12 }}
|6 |7 |8 = {{#time:F Y|2005-12 }}
|9 |10 = {{#time:j F Y|2005-12 }}
|#default = error
}}{{#if:| ({{{season}}})|}}; | }}{{#if:40| 40|}}{{#if:3|(3)|}}{{#if: 147-155|{{#if:|: [{{{article}}}]|}}{{#if:|: {{{page}}}|}}{{#if:147-155|: 147-155|}}.|}}{{#if:16226431| PMID.|}}{{#if:| PMC.|}}{{#if:10.1016/j.jdermsci.2005.08.009| DOI.|}}{{#if:| DOI.|}}{{#if:| Retrieved {{#switch:{{#invoke:String|len|s=}}
|0 |1 |2 =
|3 |4 |5 = {{#time:Y| }}
|6 |7 |8 = {{#time:F Y| }}
|9 |10 = {{#time:j F Y| }}
|#default = error
}}.|}}{{#if:|
Quote: |}} - ↑ REFjournal {{#if:Dezutter-Dambuyant|{{#if:|{{#if:C|[[{{{author-link}}}|Dezutter-Dambuyant C]]|[[{{{author-link}}}|Dezutter-Dambuyant{{#if:|, {{{first}}}|}}]]}}|{{#if:C|Dezutter-Dambuyant C|Dezutter-Dambuyant{{#if:|, {{{first}}}|}}|}}|}}|}}{{#if:Charbonnier|{{#if:|{{#if:AS|, [[{{{author2-link}}}|Charbonnier AS]]|, [[{{{author2-link}}}|Charbonnier{{#if:|, {{{first2}}}|}}]]}}|{{#if:AS|, Charbonnier AS|, Charbonnier{{#if:|, {{{first2}}}|}}|}}|}}|}}{{#if:Schmitt|{{#if:|{{#if:D|, [[{{{author3-link}}}|Schmitt D]]|, [[{{{author3-link}}}|Schmitt{{#if:|, {{{first3}}}|}}]]}}|{{#if:D|, Schmitt D|, Schmitt{{#if:|, {{{first3}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author4-link}}}|{{{last4}}} {{{init4}}}]]|, [[{{{author4-link}}}|{{{last4}}}{{#if:|, {{{first4}}}|}}]]}}|{{#if:|, {{{last4}}} {{{init4}}}|, {{{last4}}}{{#if:|, {{{first4}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author5-link}}}|{{{last5}}} {{{init5}}}]]|, [[{{{author5-link}}}|{{{last5}}}{{#if:|, {{{first5}}}|}}]]}}|{{#if:|, {{{last5}}} {{{init5}}}|, {{{last5}}}{{#if:|, {{{first5}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author6-link}}}|{{{last6}}} {{{init6}}}]]|, [[{{{author6-link}}}|{{{last6}}}{{#if:|, {{{first6}}}|}}]]}}|{{#if:|, {{{last6}}} {{{init6}}}|, {{{last6}}}{{#if:|, {{{first6}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author7-link}}}|{{{last7}}} {{{init7}}}]]|, [[{{{author7-link}}}|{{{last7}}}{{#if:|, {{{first7}}}|}}]]}}|{{#if:|, {{{last7}}} {{{init7}}}|, {{{last7}}}{{#if:|, {{{first7}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author8-link}}}|{{{last8}}} {{{init8}}}]]|, [[{{{author8-link}}}|{{{last8}}}{{#if:|, {{{first8}}}|}}]]}}|{{#if:|, {{{last8}}} {{{init8}}}|, {{{last8}}}{{#if:|, {{{first8}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author9-link}}}|{{{last9}}} {{{init9}}}]]|, [[{{{author9-link}}}|{{{last9}}}{{#if:|, {{{first9}}}|}}]]}}|{{#if:|, {{{last9}}} {{{init9}}}|, {{{last9}}}{{#if:|, {{{first9}}}|}}|}}|}}|}}{{#if:|; with {{{coauthors}}} [deprecated REFjournal parameter used: <coauthors> - please use <last2>, etc.]|}}{{#ifeq:|yes|, et al.|{{#if:Dezutter-Dambuyant|.|}}}}{{#if:| ({{{publisher}}})|}} {{#if:|[ Cellules dendritiques épithéliales et infection par HIV-1 in vivo et in vitro]{{#if:| PDF|}}{{#ifeq:|yes| (archive URL)|}}|Cellules dendritiques épithéliales et infection par HIV-1 in vivo et in vitro}}{{#if:Epithelial dendritic cells and HIV-1 infection in vivo and in vitro| [Epithelial dendritic cells and HIV-1 infection in vivo and in vitro]{{#if:French| (French)|}}|}}{{#if:Pathologie Biologie|. Pathologie Biologie{{#if:| ({{{location}}})}}.|}}{{#if:1995-12| {{#switch:{{#invoke:String|len|s=1995-12}}
|0 |1 |2 =
|3 |4 |5 = {{#time:Y|1995-12 }}
|6 |7 |8 = {{#time:F Y|1995-12 }}
|9 |10 = {{#time:j F Y|1995-12 }}
|#default = error
}}{{#if:| ({{{season}}})|}}; | }}{{#if:43| 43|}}{{#if:10|(10)|}}{{#if: 882-888|{{#if:|: [{{{article}}}]|}}{{#if:|: {{{page}}}|}}{{#if:882-888|: 882-888|}}.|}}{{#if:8786894| PMID.|}}{{#if:| PMC.|}}{{#if:| DOI.|}}{{#if:| DOI.|}}{{#if:2019-10-20| Retrieved {{#switch:{{#invoke:String|len|s=2019-10-20}}
|0 |1 |2 =
|3 |4 |5 = {{#time:Y|2019-10-20 }}
|6 |7 |8 = {{#time:F Y|2019-10-20 }}
|9 |10 = {{#time:j F Y|2019-10-20 }}
|#default = error
}}.|}}{{#if:|
Quote: |}} - ↑ REFjournal {{#if:de Witte|{{#if:|{{#if:L|[[{{{author-link}}}|de Witte L]]|[[{{{author-link}}}|de Witte{{#if:Lot|, Lot|}}]]}}|{{#if:L|de Witte L|de Witte{{#if:Lot|, Lot|}}|}}|}}|}}{{#if:Nabatov|{{#if:|{{#if:A|, [[{{{author2-link}}}|Nabatov A]]|, [[{{{author2-link}}}|Nabatov{{#if:Alexey|, Alexey|}}]]}}|{{#if:A|, Nabatov A|, Nabatov{{#if:Alexey|, Alexey|}}|}}|}}|}}{{#if:Pion|{{#if:|{{#if:M|, [[{{{author3-link}}}|Pion M]]|, [[{{{author3-link}}}|Pion{{#if:Marjorie|, Marjorie|}}]]}}|{{#if:M|, Pion M|, Pion{{#if:Marjorie|, Marjorie|}}|}}|}}|}}{{#if:Fluitsma|{{#if:|{{#if:D|, [[{{{author4-link}}}|Fluitsma D]]|, [[{{{author4-link}}}|Fluitsma{{#if:Donna|, Donna|}}]]}}|{{#if:D|, Fluitsma D|, Fluitsma{{#if:Donna|, Donna|}}|}}|}}|}}{{#if:de Jong|{{#if:|{{#if:MAWP|, [[{{{author5-link}}}|de Jong MAWP]]|, [[{{{author5-link}}}|de Jong{{#if:Marein A.W.P.|, Marein A.W.P.|}}]]}}|{{#if:MAWP|, de Jong MAWP|, de Jong{{#if:Marein A.W.P.|, Marein A.W.P.|}}|}}|}}|}}{{#if:de Gruijl|{{#if:|{{#if:T|, [[{{{author6-link}}}|de Gruijl T]]|, [[{{{author6-link}}}|de Gruijl{{#if:Tanja|, Tanja|}}]]}}|{{#if:T|, de Gruijl T|, de Gruijl{{#if:Tanja|, Tanja|}}|}}|}}|}}{{#if:Piguet|{{#if:|{{#if:V|, [[{{{author7-link}}}|Piguet V]]|, [[{{{author7-link}}}|Piguet{{#if:Vincent|, Vincent|}}]]}}|{{#if:V|, Piguet V|, Piguet{{#if:Vincent|, Vincent|}}|}}|}}|}}{{#if:van Kooyk|{{#if:|{{#if:Y|, [[{{{author8-link}}}|van Kooyk Y]]|, [[{{{author8-link}}}|van Kooyk{{#if:Yvette|, Yvette|}}]]}}|{{#if:Y|, van Kooyk Y|, van Kooyk{{#if:Yvette|, Yvette|}}|}}|}}|}}{{#if:Geijtenbeek|{{#if:|{{#if:TBH|, [[{{{author9-link}}}|Geijtenbeek TBH]]|, [[{{{author9-link}}}|Geijtenbeek{{#if:Teunis B.H.|, Teunis B.H.|}}]]}}|{{#if:TBH|, Geijtenbeek TBH|, Geijtenbeek{{#if:Teunis B.H.|, Teunis B.H.|}}|}}|}}|}}{{#if:|; with {{{coauthors}}} [deprecated REFjournal parameter used: <coauthors> - please use <last2>, etc.]|}}{{#ifeq:|yes|, et al.|{{#if:de Witte|.|}}}}{{#if:| ({{{publisher}}})|}} {{#if:http://www.circumcisionandhiv.com/files/de_Witte_2007.pdf%7CLangerin is a natural barrier to HIV-1 transmission by Langerhans cells{{#if:PDF| PDF|}}{{#ifeq:|yes| (archive URL)|}}|Langerin is a natural barrier to HIV-1 transmission by Langerhans cells}}{{#if:| [{{{trans-title}}}]{{#if:| ({{{language}}})|}}|}}{{#if:Nature Medicine|. Nature Medicine{{#if:| ({{{location}}})}}.|}}{{#if:2007-03-04| {{#switch:{{#invoke:String|len|s=2007-03-04}}
|0 |1 |2 =
|3 |4 |5 = {{#time:Y|2007-03-04 }}
|6 |7 |8 = {{#time:F Y|2007-03-04 }}
|9 |10 = {{#time:j F Y|2007-03-04 }}
|#default = error
}}{{#if:| ({{{season}}})|}}; | }}{{#if:13| 13|}}{{#if:3|(3)|}}{{#if: 367-71|{{#if:|: [{{{article}}}]|}}{{#if:|: {{{page}}}|}}{{#if:367-71|: 367-71|}}.|}}{{#if:17334373| PMID.|}}{{#if:10.1038/nm1541| PMC.|}}{{#if:10.1038/nm1541| DOI.|}}{{#if:| DOI.|}}{{#if:2022-10-06| Retrieved {{#switch:{{#invoke:String|len|s=2022-10-06}}
|0 |1 |2 =
|3 |4 |5 = {{#time:Y|2022-10-06 }}
|6 |7 |8 = {{#time:F Y|2022-10-06 }}
|9 |10 = {{#time:j F Y|2022-10-06 }}
|#default = error
}}.|}}{{#if:|
Quote:{{{quote}}}
|}} - ↑ REFnews {{#if:Mundell|{{#if:|[[{{{author-link}}}|Mundell{{#if:E. J.|, E. J.|}}]]|Mundell{{#if:E. J.|, E. J.|}}|}}|}}{{#if:| / {{#if:|[[{{{author2-link}}}|{{#if:|{{{first2}}}|}} {{{last2}}}]]|{{#if:|{{{first2}}}|}} {{{last2}}}}}}}{{#if:| / {{#if:|[[{{{author3-link}}}|{{#if:|{{{first3}}}|}} {{{last3}}}]]|{{#if:|{{{first3}}}|}} {{{last3}}}}}}}{{#if:| / {{#if:|[[{{{author4-link}}}|{{#if:|{{{first4}}}|}} {{{last4}}}]]|{{#if:|{{{first4}}}|}} {{{last4}}}}}}}{{#if:| / {{#if:|[[{{{author5-link}}}|{{#if:|{{{first5}}}|}} {{{last5}}}]]|{{#if:|{{{first5}}}|}} {{{last5}}}}}}}{{#if:| / {{#if:|[[{{{author6-link}}}|{{#if:|{{{first6}}}|}} {{{last6}}}]]|{{#if:|{{{first6}}}|}} {{{last6}}}}}}}{{#if:| / {{#if:|[[{{{author7-link}}}|{{#if:|{{{first7}}}|}} {{{last7}}}]]|{{#if:|{{{first7}}}|}} {{{last7}}}}}}}{{#if:| / {{#if:|[[{{{author8-link}}}|{{#if:|{{{first8}}}|}} {{{last8}}}]]|{{#if:|{{{first8}}}|}} {{{last8}}}}}}}{{#if:| / {{#if:|[[{{{author9-link}}}|{{#if:|{{{first9}}}|}} {{{last9}}}]]|{{#if:|{{{first9}}}|}} {{{last9}}}}}}}{{#if:|; with {{{coauthors}}} [deprecated REFjournal parameter used: <coauthors> - please use <last2>, etc.]|}}{{#ifeq:|yes|, et al.|}}{{#if:2007-03-05|{{#if:Mundell| |}}({{#switch:{{#invoke:String|len|s=2007-03-05}}
|0 |1 |2 =
|3 |4 |5 = {{#time:Y|2007-03-05 }}
|6 |7 |8 = {{#time:F Y|2007-03-05 }}
|9 |10 = {{#time:j F Y|2007-03-05 }}
|#default = error
}}). |{{#if:|{{#if:Mundell| |}}({{{season}}}). |{{#if:Mundell|. |}}}}}}{{#if:http://health.msn.com/health-topics/articlepage.aspx?cp-documentid=100157237%7C"Scientists Discover 'Natural Barrier' to HIV"{{#if: | File:Icons-mini-file pdf.svg|}}{{#if:| (PDF)|}}|"Scientists Discover 'Natural Barrier' to HIV"{{#if:| File:Icons-mini-file acrobat.gif|}}{{#if:| (PDF)|}}}}{{#ifeq:|yes| (archive URL)|}}{{#if:| [{{{trans-title}}}]{{#if:| ({{{language}}})|}}|}}{{#if:HealthDay|, HealthDay|}}{{#if:MSN|, MSN|}}{{#if:2012-06-27|. Retrieved {{#switch:{{#invoke:String|len|s=2012-06-27}}
|0 |1 |2 =
|3 |4 |5 = {{#time:Y|2012-06-27 }}
|6 |7 |8 = {{#time:F Y|2012-06-27 }}
|9 |10 = {{#time:j F Y|2012-06-27 }}
|#default = error
}}|}}.{{#if:|
Quote: |}} - ↑ REFjournal {{#if:Mayan|{{#if:|{{#if:M|[[|Mayan M]]|[[|Mayan{{#if:Madhur|, Madhur|}}]]}}|{{#if:M|Mayan M|Mayan{{#if:Madhur|, Madhur|}}|}}|}}|}}{{#if:Hamilton|{{#if:|{{#if:RJ|, [[|Hamilton RJ]]|, [[|Hamilton{{#if:Robert J.|, Robert J.|}}]]}}|{{#if:RJ|, Hamilton RJ|, Hamilton{{#if:Robert J.|, Robert J.|}}|}}|}}|}}{{#if:Juurlink|{{#if:|{{#if:DN|, [[|Juurlink DN]]|, [[|Juurlink{{#if:David N.|, David N.|}}]]}}|{{#if:DN|, Juurlink DN|, Juurlink{{#if:David N.|, David N.|}}|}}|}}|}}{{#if:Austin|{{#if:|{{#if:PC|, [[|Austin PC]]|, [[|Austin{{#if:Peter C.|, Peter C.|}}]]}}|{{#if:PC|, Austin PC|, Austin{{#if:Peter C.|, Peter C.|}}|}}|}}|}}{{#if:Jarvi|{{#if:|{{#if:KA|, [[|Jarvi KA]]|, [[|Jarvi{{#if:Keith A.|, Keith A.|}}]]}}|{{#if:KA|, Jarvi KA|, Jarvi{{#if:Keith A.|, Keith A.|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author6-link}}}|{{{last6}}} {{{init6}}}]]|, [[{{{author6-link}}}|{{{last6}}}{{#if:|, {{{first6}}}|}}]]}}|{{#if:|, {{{last6}}} {{{init6}}}|, {{{last6}}}{{#if:|, {{{first6}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author7-link}}}|{{{last7}}} {{{init7}}}]]|, [[{{{author7-link}}}|{{{last7}}}{{#if:|, {{{first7}}}|}}]]}}|{{#if:|, {{{last7}}} {{{init7}}}|, {{{last7}}}{{#if:|, {{{first7}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author8-link}}}|{{{last8}}} {{{init8}}}]]|, [[{{{author8-link}}}|{{{last8}}}{{#if:|, {{{first8}}}|}}]]}}|{{#if:|, {{{last8}}} {{{init8}}}|, {{{last8}}}{{#if:|, {{{first8}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author9-link}}}|{{{last9}}} {{{init9}}}]]|, [[{{{author9-link}}}|{{{last9}}}{{#if:|, {{{first9}}}|}}]]}}|{{#if:|, {{{last9}}} {{{init9}}}|, {{{last9}}}{{#if:|, {{{first9}}}|}}|}}|}}|}}{{#if:|; with {{{coauthors}}} [deprecated REFjournal parameter used: <coauthors> - please use <last2>, etc.]|}}{{#ifeq:no|yes|, et al.|{{#if:Mayan|.|}}}}{{#if:| ({{{publisher}}})|}} {{#if:https://www.auajournals.org/doi/pdf/10.1097/JU.0000000000002234%7CCircumcision and Risk of HIV Among Males From Ontario, Canada{{#if:| PDF|}}{{#ifeq:|yes| (archive URL)|}}|Circumcision and Risk of HIV Among Males From Ontario, Canada}}{{#if:| [{{{trans-title}}}]{{#if:| ({{{language}}})|}}|}}{{#if:J Urol|. J Urol{{#if:| ({{{location}}})}}.|}}{{#if:2021-09-23| {{#switch:{{#invoke:String|len|s=2021-09-23}}
|0 |1 |2 =
|3 |4 |5 = {{#time:Y|2021-09-23 }}
|6 |7 |8 = {{#time:F Y|2021-09-23 }}
|9 |10 = {{#time:j F Y|2021-09-23 }}
|#default = error
}}{{#if:| ({{{season}}})|}}; | }}{{#if:| {{{volume}}}|}}{{#if:|({{{issue}}})|}}{{#if: |{{#if:|: [{{{article}}}]|}}{{#if:|: {{{page}}}|}}{{#if:|: {{{pages}}}|}}.|}}{{#if:34551593| PMID.|}}{{#if:| PMC.|}}{{#if:10.1097/JU.0000000000002234| DOI.|}}{{#if:| DOI.|}}{{#if:2022-08-21| Retrieved {{#switch:{{#invoke:String|len|s=2022-08-21}}
|0 |1 |2 =
|3 |4 |5 = {{#time:Y|2022-08-21 }}
|6 |7 |8 = {{#time:F Y|2022-08-21 }}
|9 |10 = {{#time:j F Y|2022-08-21 }}
|#default = error
}}.|}}{{#if:We found that circumcision was not independently associated with the risk of acquiring HIV among men from Ontario, Canada.|
Quote:We found that circumcision was not independently associated with the risk of acquiring HIV among men from Ontario, Canada.
|}} - ↑ REFjournal {{#if:Frisch|{{#if:Morten Frisch|{{#if:M|Frisch M|Frisch{{#if:Morten|, Morten|}}}}|{{#if:M|Frisch M|Frisch{{#if:Morten|, Morten|}}|}}|}}|}}{{#if:Simonsen|{{#if:|{{#if:J|, [[|Simonsen J]]|, [[|Simonsen{{#if:Jacob|, Jacob|}}]]}}|{{#if:J|, Simonsen J|, Simonsen{{#if:Jacob|, Jacob|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author3-link}}}|{{{last3}}} {{{init3}}}]]|, [[{{{author3-link}}}|{{{last3}}}{{#if:|, {{{first3}}}|}}]]}}|{{#if:|, {{{last3}}} {{{init3}}}|, {{{last3}}}{{#if:|, {{{first3}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author4-link}}}|{{{last4}}} {{{init4}}}]]|, [[{{{author4-link}}}|{{{last4}}}{{#if:|, {{{first4}}}|}}]]}}|{{#if:|, {{{last4}}} {{{init4}}}|, {{{last4}}}{{#if:|, {{{first4}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author5-link}}}|{{{last5}}} {{{init5}}}]]|, [[{{{author5-link}}}|{{{last5}}}{{#if:|, {{{first5}}}|}}]]}}|{{#if:|, {{{last5}}} {{{init5}}}|, {{{last5}}}{{#if:|, {{{first5}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author6-link}}}|{{{last6}}} {{{init6}}}]]|, [[{{{author6-link}}}|{{{last6}}}{{#if:|, {{{first6}}}|}}]]}}|{{#if:|, {{{last6}}} {{{init6}}}|, {{{last6}}}{{#if:|, {{{first6}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author7-link}}}|{{{last7}}} {{{init7}}}]]|, [[{{{author7-link}}}|{{{last7}}}{{#if:|, {{{first7}}}|}}]]}}|{{#if:|, {{{last7}}} {{{init7}}}|, {{{last7}}}{{#if:|, {{{first7}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author8-link}}}|{{{last8}}} {{{init8}}}]]|, [[{{{author8-link}}}|{{{last8}}}{{#if:|, {{{first8}}}|}}]]}}|{{#if:|, {{{last8}}} {{{init8}}}|, {{{last8}}}{{#if:|, {{{first8}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author9-link}}}|{{{last9}}} {{{init9}}}]]|, [[{{{author9-link}}}|{{{last9}}}{{#if:|, {{{first9}}}|}}]]}}|{{#if:|, {{{last9}}} {{{init9}}}|, {{{last9}}}{{#if:|, {{{first9}}}|}}|}}|}}|}}{{#if:|; with {{{coauthors}}} [deprecated REFjournal parameter used: <coauthors> - please use <last2>, etc.]|}}{{#ifeq:no|yes|, et al.|{{#if:Frisch|.|}}}}{{#if:| ({{{publisher}}})|}} {{#if:https://link.springer.com/article/10.1007/s10654-021-00809-6%7CNon-therapeutic male circumcision in infancy or childhood and risk of human immunodeficiency virus and other sexually transmitted infections: national cohort study in Denmark{{#if:| PDF|}}{{#ifeq:|yes| (archive URL)|}}|Non-therapeutic male circumcision in infancy or childhood and risk of human immunodeficiency virus and other sexually transmitted infections: national cohort study in Denmark}}{{#if:| [{{{trans-title}}}]{{#if:| ({{{language}}})|}}|}}{{#if:Eur J Epidemiol|. Eur J Epidemiol{{#if:| ({{{location}}})}}.|}}{{#if:2021-09-26| {{#switch:{{#invoke:String|len|s=2021-09-26}}
|0 |1 |2 =
|3 |4 |5 = {{#time:Y|2021-09-26 }}
|6 |7 |8 = {{#time:F Y|2021-09-26 }}
|9 |10 = {{#time:j F Y|2021-09-26 }}
|#default = error
}}{{#if:| ({{{season}}})|}}; | }}{{#if:37| 37|}}{{#if:|({{{issue}}})|}}{{#if: 251–9|{{#if:|: [{{{article}}}]|}}{{#if:|: {{{page}}}|}}{{#if:251–9|: 251–9|}}.|}}{{#if:34564796| PMID.|}}{{#if:| PMC.|}}{{#if:10.1007/s10654-021-00809-6| DOI.|}}{{#if:| DOI.|}}{{#if:2022-01-16| Retrieved {{#switch:{{#invoke:String|len|s=2022-01-16}}
|0 |1 |2 =
|3 |4 |5 = {{#time:Y|2022-01-16 }}
|6 |7 |8 = {{#time:F Y|2022-01-16 }}
|9 |10 = {{#time:j F Y|2022-01-16 }}
|#default = error
}}.|}}{{#if:|
Quote:{{{quote}}}
|}} - ↑ REFjournal {{#if:Garenne|{{#if:Michel Garenne|{{#if:M|Garenne M|Garenne{{#if:Michel|, Michel|}}}}|{{#if:M|Garenne M|Garenne{{#if:Michel|, Michel|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author2-link}}}|{{{last2}}} {{{init2}}}]]|, [[{{{author2-link}}}|{{{last2}}}{{#if:|, {{{first2}}}|}}]]}}|{{#if:|, {{{last2}}} {{{init2}}}|, {{{last2}}}{{#if:|, {{{first2}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author3-link}}}|{{{last3}}} {{{init3}}}]]|, [[{{{author3-link}}}|{{{last3}}}{{#if:|, {{{first3}}}|}}]]}}|{{#if:|, {{{last3}}} {{{init3}}}|, {{{last3}}}{{#if:|, {{{first3}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author4-link}}}|{{{last4}}} {{{init4}}}]]|, [[{{{author4-link}}}|{{{last4}}}{{#if:|, {{{first4}}}|}}]]}}|{{#if:|, {{{last4}}} {{{init4}}}|, {{{last4}}}{{#if:|, {{{first4}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author5-link}}}|{{{last5}}} {{{init5}}}]]|, [[{{{author5-link}}}|{{{last5}}}{{#if:|, {{{first5}}}|}}]]}}|{{#if:|, {{{last5}}} {{{init5}}}|, {{{last5}}}{{#if:|, {{{first5}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author6-link}}}|{{{last6}}} {{{init6}}}]]|, [[{{{author6-link}}}|{{{last6}}}{{#if:|, {{{first6}}}|}}]]}}|{{#if:|, {{{last6}}} {{{init6}}}|, {{{last6}}}{{#if:|, {{{first6}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author7-link}}}|{{{last7}}} {{{init7}}}]]|, [[{{{author7-link}}}|{{{last7}}}{{#if:|, {{{first7}}}|}}]]}}|{{#if:|, {{{last7}}} {{{init7}}}|, {{{last7}}}{{#if:|, {{{first7}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author8-link}}}|{{{last8}}} {{{init8}}}]]|, [[{{{author8-link}}}|{{{last8}}}{{#if:|, {{{first8}}}|}}]]}}|{{#if:|, {{{last8}}} {{{init8}}}|, {{{last8}}}{{#if:|, {{{first8}}}|}}|}}|}}|}}{{#if:|{{#if:|{{#if:|, [[{{{author9-link}}}|{{{last9}}} {{{init9}}}]]|, [[{{{author9-link}}}|{{{last9}}}{{#if:|, {{{first9}}}|}}]]}}|{{#if:|, {{{last9}}} {{{init9}}}|, {{{last9}}}{{#if:|, {{{first9}}}|}}|}}|}}|}}{{#if:|; with {{{coauthors}}} [deprecated REFjournal parameter used: <coauthors> - please use <last2>, etc.]|}}{{#ifeq:|yes|, et al.|{{#if:Garenne|.|}}}}{{#if:| ({{{publisher}}})|}} {{#if:https://pubmed.ncbi.nlm.nih.gov/35373731/%7CChanging relationships between HIV prevalence and circumcision in Lesotho{{#if:| PDF|}}{{#ifeq:|yes| (archive URL)|}}|Changing relationships between HIV prevalence and circumcision in Lesotho}}{{#if:| [{{{trans-title}}}]{{#if:| ({{{language}}})|}}|}}{{#if:J Biosoc Sci|. J Biosoc Sci{{#if:| ({{{location}}})}}.|}}{{#if:2022-04-04| {{#switch:{{#invoke:String|len|s=2022-04-04}}
|0 |1 |2 =
|3 |4 |5 = {{#time:Y|2022-04-04 }}
|6 |7 |8 = {{#time:F Y|2022-04-04 }}
|9 |10 = {{#time:j F Y|2022-04-04 }}
|#default = error
}}{{#if:| ({{{season}}})|}}; | }}{{#if:online ahead of print| online ahead of print|}}{{#if:|({{{issue}}})|}}{{#if: 1-16|{{#if:|: [{{{article}}}]|}}{{#if:|: {{{page}}}|}}{{#if:1-16|: 1-16|}}.|}}{{#if:35373731| PMID.|}}{{#if:| PMC.|}}{{#if:10.1017/S0021932022000153| DOI.|}}{{#if:| DOI.|}}{{#if:2022-10-28| Retrieved {{#switch:{{#invoke:String|len|s=2022-10-28}}
|0 |1 |2 =
|3 |4 |5 = {{#time:Y|2022-10-28 }}
|6 |7 |8 = {{#time:F Y|2022-10-28 }}
|9 |10 = {{#time:j F Y|2022-10-28 }}
|#default = error
}}.|}}{{#if:|
Quote:{{{quote}}}
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|9 |10 = {{#time:j F Y|2022-10-26 }}
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|3 |4 |5 = {{#time:Y|2022-10-27 }}
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|9 |10 = {{#time:j F Y|2022-10-27 }}
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