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'''Professor Sir {{FULLPAGENAME}}''', M.D., F.R.C.P., ({{LifeData |birth=1892-03-19 |birthplace= |birthcountry= |death=1954-05-26}}) was a prominent British paediatrician in the early twentieth century.  He practised established his practice at Newcastle upon Tyne where he developed an interest in social paediatrics. [[Douglas Gairdner]] joined him in 1945 as his first assistantand stayed until 1948 during which time Spence served as a mentor to the younger Gairdner.