Changes

Fleiss et al. (1998) have listed numerous immunological functions of the foreskin that help to protect the human body against [[infection]]. The foreskin maintains the moistness of the [[preputial mucosa]] and the [[glans penis]] by [[transudation]]. The sub-preputial moisture contains cathepsin B, chymotrypsin, neutrophil elastase, cytokines, and lysozyme, which has the capacity to destroy the cell walls of bacteria. The preputial muscles keep the tip of the foreskin closed to keep moisture in, while also keeping pathogens and other contaminants out pathogens.<ref name="fleiss-hodges-vanhowe1998"/>