Difference between revisions of "Microbiome"
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The '''microbiome''' is the complete genetic content of all the microorganisms that typically inhabit a particular environment, especially a site on or in the body, such as the skin or the gastrointestinal tract.<ref>{{REFweb | The '''microbiome''' is the complete genetic content of all the microorganisms that typically inhabit a particular environment, especially a site on or in the body, such as the skin or the gastrointestinal tract.<ref>{{REFweb | ||
|url=https://medical-dictionary.thefreedictionary.com/Microbiome | |url=https://medical-dictionary.thefreedictionary.com/Microbiome | ||
| Line 11: | Line 10: | ||
}}</ref> | }}</ref> | ||
| + | The Human Microbiome Project Consortium (2012) reported a remarkable diversity in the healthy human microbiome.<ref>{{REFjournal | ||
| + | |last=Human Microbiome Project Consortium | ||
| + | |first= | ||
| + | |init= | ||
| + | |author-link= | ||
| + | |etal=no | ||
| + | |title=Structure, function and diversity of the healthy human microbiome | ||
| + | |trans-title= | ||
| + | |language= | ||
| + | |journal=Nature | ||
| + | |location= | ||
| + | |date=2012-06-13 | ||
| + | |volume=486 | ||
| + | |issue=7402 | ||
| + | |article= | ||
| + | |pages=207-14 | ||
| + | |url=https://www.nature.com/articles/nature11234 | ||
| + | |archived= | ||
| + | |quote= | ||
| + | |pubmedID=22699609 | ||
| + | |pubmedCID=3564958 | ||
| + | |DOI=10.1038/nature11234 | ||
| + | |accessdate=2023-09-24 | ||
| + | }}</ref> | ||
| + | |||
| + | Segre (2023) pointed out that the microbiome is "good" and contributes to human health in various ways, such as digestion of food and prevention of colonization by pathogens.<ref name="segre2023">{{REFweb | ||
| + | |url=https://www.genome.gov/genetics-glossary/Microbiome | ||
| + | |title=Microbiome | ||
| + | |last=Segre | ||
| + | |first=Julie | ||
| + | |init= | ||
| + | |publisher=National Human Genome Research Institute | ||
| + | |date=2023-09-23 | ||
| + | |accessdate=2023-09-24 | ||
| + | }}</ref> | ||
| + | |||
| + | == Penile microbiome == | ||
| + | Mishra et al. (2023) surveyed the microbiome and mycobiome of eleven toilet-trained pediatric patients before and after elective non-therapeutic [[circumcision]]. Circumcision amputates the [[foreskin]] and destroys the [[preputial sac]] where the microbiome is found.<ref name="cold-taylor1999">{{ColdCJ TaylorJR 1999}}</ref> The authors reported a "significant drop" in the bacterial and fungal population after [[circumcision]], but did ''not'' report any improvement in patient health.<ref>{{REFjournal | ||
| + | |last=Mishra | ||
| + | |first= | ||
| + | |init=K | ||
| + | |author-link= | ||
| + | |last2=Isali | ||
| + | |first2= | ||
| + | |init2=I | ||
| + | |author2-link= | ||
| + | |last3=Sidhani | ||
| + | |first3= | ||
| + | |init3=M | ||
| + | |author3-link= | ||
| + | |last4=Prunty | ||
| + | |first4= | ||
| + | |init4=M | ||
| + | |author4-link= | ||
| + | |etal=yes | ||
| + | |title=Characterization of Changes in Penile Microbiome Following Pediatric Circumcision | ||
| + | |trans-title= | ||
| + | |language= | ||
| + | |journal=Eur Urol Focus | ||
| + | |location= | ||
| + | |date=2023-07 | ||
| + | |volume=9 | ||
| + | |issue=4 | ||
| + | |pages=660-80 | ||
| + | |url=https://www.eu-focus.europeanurology.com/article/S2405-4569(22)00290-5/fulltext | ||
| + | |archived= | ||
| + | |quote= | ||
| + | |pubmedID=36566099 | ||
| + | |pubmedCID= | ||
| + | |DOI=10.1016/j.euf.2022.12.007 | ||
| + | |accessdate=2023-09-25 | ||
| + | }}</ref> | ||
| + | {{SEEALSO}} | ||
| + | * [[Immunological and protective function of the foreskin]] | ||
{{REF}} | {{REF}} | ||
[[Category:Medical term]] | [[Category:Medical term]] | ||
| − | + | [[Category:Physiology]] | |
Latest revision as of 14:31, 26 April 2024
The microbiome is the complete genetic content of all the microorganisms that typically inhabit a particular environment, especially a site on or in the body, such as the skin or the gastrointestinal tract.[1]
The Human Microbiome Project Consortium (2012) reported a remarkable diversity in the healthy human microbiome.[2]
Segre (2023) pointed out that the microbiome is "good" and contributes to human health in various ways, such as digestion of food and prevention of colonization by pathogens.[3]
Penile microbiome
Mishra et al. (2023) surveyed the microbiome and mycobiome of eleven toilet-trained pediatric patients before and after elective non-therapeutic circumcision. Circumcision amputates the foreskin and destroys the preputial sac where the microbiome is found.[4] The authors reported a "significant drop" in the bacterial and fungal population after circumcision, but did not report any improvement in patient health.[5]
See also
References
- ↑
microbiome
, The Free Dictionary by Farlex. Retrieved 24 September 2023. - ↑
Human Microbiome Project Consortium. Structure, function and diversity of the healthy human microbiome. Nature. 13 June 2012; 486(7402): 207-14. PMID. PMC. DOI. Retrieved 24 September 2023.
- ↑ Segre, Julie (23 September 2023).
Microbiome
, National Human Genome Research Institute. Retrieved 24 September 2023. - ↑ Cold CJ, Taylor JR. The prepuce. BJU Int. January 1999; 83, Suppl. 1: 34-44. PMID. DOI. Retrieved 8 July 2021.
- ↑ Mishra K, Isali I, Sidhani M, Prunty M, et al. Characterization of Changes in Penile Microbiome Following Pediatric Circumcision. Eur Urol Focus. July 2023; 9(4): 660-80. PMID. DOI. Retrieved 25 September 2023.
