Foreskin regeneration
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Foreskin regeneration is the term applied to the creation of a foreskin for those men who have lost their foreskin to circumcision by the application of organ regeneration science.
Foreskin regeneration remains experimental in the Spring of 2024 as no foreskin has yet been regenerated. It would use a different process from foreskin restoration as has been practiced since ancient times.
Foreskin regeneration has been promoted by Vincenzo Aiello of Rome, Italy, who has created an Italian charitable organization, Foregen, to advance the development of foreskin regeneration.
Progress reports
- Foregen announced in 2018 that it had completed a decellularized extracellular matrix–based biomaterial scaffold, which is to be used in foreskin regeneration.[1]
- Sig. Aiello (April 2023) announced the successful completion of animal trials using sheep.
- Novatna et al. (2023) compared two different methods of decellularization techniques of human foreskin and found that both methods are satisfactory.[2]
Video
Progress update by Sig. Aiello
References
- ↑
Purpura V, Bondioli E, Cunningham EC, et al. The development of a decellularized extracellular matrix–based biomaterial scaffold derived from human foreskin for the purpose of foreskin reconstruction in circumcised males. J Tissue Eng. 22 December 2018; PMID. PMC. DOI. Retrieved 16 March 2024.
- ↑ Novatna O, Varchulova Novakova, V, Galfiova P, Lorencova P, Klein M, Žiaran A, Kuniakova M. Decellularization techniques of human foreskin for tissue engineering application. Physiol Res. 27 October 2023; 72(S3): S287-S297. PMID. PMC. DOI. Retrieved 16 March 2023.
