Foregen: Difference between revisions

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[[Image:Foregen logo.png|right]]
[[Image:Foregen logo.png|right]]
'''Foregen'''’s goal is to heal the physical detriment that is inherent to [[circumcision]].


'''Foregen''' is a registered Italian charity. Foregen was founded by Sig. [[Vincenzo Aiello]] of Italy to promote and arrange a clinical trial that would use regenerative techniques to regrow the tissue removed at circumcision. Foregen's goal is to heal the physical loss of functional tissue that is inherent to [[circumcision]]. Foregen's principal office is at Via Campi Flegrei 59, 00141 Rome, Italy.
==History==
After dismissing many unsatisfactory proposals from research institutions, Foregen decided to conduct its own research and clinical trials. Foregen has applied regenerative techniques to animal foreskins and will continue research on adult human foreskins.
Foregen announced in 2018 that it had completed a decellularized extracellular matrix–based biomaterial scaffold, which is to be used in foreskin regeneration.<ref>{{REFjournal
|last=Purpura
|first=Valeria
|init=V
|author-link=
|last2=Bondioli
|first2=Elena
|init2=E
|author2-link=
|last3=Cunningham
|first3=Eric J.
|init3=EC
|author3-link=
|etal=yes
|title=The development of a decellularized extracellular matrix–based biomaterial scaffold derived from human foreskin for the purpose of foreskin reconstruction in circumcised males
|journal=J Tissue Eng
|location=
|date=2018-12-22
|volume=
|issue=
|pages=
|url=https://journals.sagepub.com/doi/full/10.1177/2041731418812613
|quote=
|pubmedID=30622692
|pubmedCID=6304708
|DOI=10.1177/2041731418812613
|accessdate=2020-02-09
}}</ref>
Foregen announced in December 2021 that it is hoped that clinical trials would commence in April 2023.<ref>{{REFweb
|url=https://www.foregen.org/clinical-trials
|title=Human Clinical Trials Application Form
|last=
|first=
|date=2021-12
|accessdate=2021-12-20
}}</ref>
==Regenerative medicine==
Regenerative medical techniques now offer a greater possibility than ever to regrow human tissue, especially dermal tissue, lost in prior trauma. Regenerative medicine has been used to recreate vaginas of women with some congenital conditions<ref>{{REFnews
Regenerative medical techniques now offer a greater possibility than ever to regrow human tissue, especially dermal tissue, lost in prior trauma. Regenerative medicine has been used to recreate vaginas of women with some congenital conditions<ref>{{REFnews
  |last=Richardson
  |last=Richardson
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  |date=2014-04-22
  |date=2014-04-22
  |accessdate=2015-07-15
  |accessdate=2015-07-15
}}</ref>. However, regenerative medicine has not yet been applied to those who have been circumcised and no longer wish to be.
}}</ref>. However, regenerative medicine has not yet been applied to those who have been circumcised, but no longer wish to be.
 
==History==
Foregen was founded by Sig. [[Vincenzo Aiello]] of Italy to promote and arrange a clinical trial that would use regenerative techniques to regrow the tissue removed at circumcision. After dismissing many unsatisfactory proposals from research institutions, Foregen decided to conduct its own research and clinical trials. Foregen has applied regenerative techniques to animal foreskins and will continue research on adult human foreskins.


==Goals==
==Goals==
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==Progress reports==
==Progress reports==


Foregen announced in 2018 that it had completed a decellularized extracellular matrix–based biomaterial scaffold, which is to be used in foreskin regeneration.<ref>{{REFjournal
 
|last=Purpura
|first=Valeria
|init=V
|author-link=
|last2=Bondioli
|first2=Elena
|init2=E
|author2-link=
|last3=Cunningham
|first3=Eric J.
|init3=EC
|author3-link=
|etal=yes
|title=The development of a decellularized extracellular matrix–based biomaterial scaffold derived from human foreskin for the purpose of foreskin reconstruction in circumcised males
|journal=J Tissue Eng
|location=
|date=2018-12-22
|volume=
|issue=
|pages=
|url=https://journals.sagepub.com/doi/full/10.1177/2041731418812613
|quote=
|pubmedID=30622692
|pubmedCID=6304708
|DOI=10.1177/2041731418812613
|accessdate=2020-02-09
}}</ref>
== Social media ==
== Social media ==
* [https://www.youtube.com/channel/UCUPHstb4Zzc-e1lbJVrT5HA Youtube Channel]
* [https://www.youtube.com/channel/UCUPHstb4Zzc-e1lbJVrT5HA Youtube Channel]