Foregen

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Foregen’s goal is to heal the physical detriment that is inherent to circumcision.

Foregen logo.png

Regenerative medical techniques now offer a greater possibility than ever to regrow human tissue, especially dermal tissue, lost in prior trauma. Regenerative medicine has been used to recreate vaginas of women with some congenital conditions[1]. Experiments have been performed to regenerate the penis of rabbits.[2] [3][4] Also progress has been made in penile transplants[5] [6] and phalloplasties[7]. However, regenerative medicine has not yet been applied to those who have been circumcised and no longer wish to be.

Contents

History

Foregen was founded by Sig. Vincenzo Aiello of Italy to promote and arrange a clinical trial that would use regenerative techniques to regrow the tissue removed at circumcision. After dismissing many unsatisfactory proposals from research institutions, Foregen decided to conduct its own research and clinical trials. Foregen has applied regenerative techniques to animal foreskins and will continue research on adult human foreskins.

Goals

Foregen’s tasks are:

  • To experiment with animal tissue to obtain a viable method of foreskin regeneration
  • To apply the experience from animal experiments to regenerate human foreskins
  • To advance onto clinical trials once Foregen proves that regenerating human foreskin is possible

Foregen is a charity

Foregen™ was created in 2010 thanks to donor funds. Foregen operates in the United States and Europe. Its head office is in Rome, Italy, where it is a registered charity (Reg. No. 6482, Serie 1T, 2010). See original founding documents here. Foregen is also tax-exempt under section 501(c)(3) of the Internal Revenue Code and is headed by a board of charitable directors with participants and donors across both continents and beyond.

For more information on the science behind Foregen, read: The science of regeneration

Video

Message from Foregen's president, Vincenzo Aiello.




Progress reports

Foregen announced in 2018 that it had completed a decellularized extracellular matrix–based biomaterial scaffold, which is to be used in foreskin regeneration.[8]

Social media

Foregen in the media

See also

External links

References

  1.   Richardson, Karen (10 April 2014)."Laboratory-Grown Vaginas Implanted in Patients, Scientists Report", Wake Forest Baptist Medical Center. Retrieved 15 July 2015.
  2.   Geggel, Laura (9 October 2014)."Scientists developing lab-grown penis for transplant", LiveScience, CBS News. Retrieved 15 July 2015.
  3.   "Engineered Penile Erectile Tissue", Wake Forest School of Medicine. Retrieved 15 July 2015.
  4.   Mohammadi, Dara (4 October 2014)."The lab-grown penis: approaching a medical milestone", The Guardian. Retrieved 15 July 2015.
  5.   Smith, David (13 March 2015)."Man gets world's first successful penis transplant after botched circumcision", The Guardian. Retrieved 15 July 2015.
  6.   Feltman, Rachel (12 June 2015)."Man who had world's first penis transplant to become a father", The Independent. Retrieved 15 July 2015.
  7.   Ho, Vivian (22 April 2014)."Man may be 1st to father child with reconstructed penis", SFGate. Retrieved 15 July 2015.
  8.   Purpura, Valeria, Bondioli, Elena, Cunningham, Eric J., et al. The development of a decellularized extracellular matrix–based biomaterial scaffold derived from human foreskin for the purpose of foreskin reconstruction in circumcised males. J Tissue Eng. 22 December 2018; PMID. PMC. DOI. Retrieved 9 February 2020.