How Does Circumcision Affect Your Penis?

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By DNews
How Does Circumcision Affect Your Penis? provides information on the changes that occur in the microbiome[1] of the penis after circumcision, however it is otherwise inaccurate.


This video mentions a "Mayo clinic study". This study was not performed by Mayo clinic, or at the Mayo clinic locations, or by its staff, or commissioned by Mayo clinic. This was a very biased paper submitted by pro-circumcision advocates Brian J. Morris and Thomas E. Wiswell to Mayo Clinic Proceedings.

This dated video contains totally inaccurate information about circumcision and HIV infection. The Langerhans cells in the foreskin actually protect against HIV infection. deWitte et. al. (2007) found that not only are Langerhans cells found all over the body and that their complete removal is virtually impossible, but furthermore, deWitte found that Langerhans cells that are present in the foreskin produce Langerin, a substance that has been proven to kill the HIV virus on contact, acting as a natural barrier to HIV-1 transmission by Langerhans cells.[2]


  1. The microbiome is the collection of all microbes, such as bacteria, fungi, viruses, and their genes, that naturally live on our bodies and inside us. Although microbes are so small that they require a microscope to see them, they contribute in big ways to human health and wellness. They protect us against pathogens, help our immune system develop, and enable us to digest food to produce energy.
  2. REFjournal de Witte L, Nabatov A, Pion M, Fluitsma D, de Jong MAWP, de Gruijl T, Piguet V, van Kooyk Y, Geijtenbeek TBH. Langerin is a natural barrier to HIV-1 transmission by Langerhans cells PDF. Nature Medicine. 4 March 2007; 13(3): 367-71. PMID. PMC. DOI. Retrieved 6 October 2022.