Difference between revisions of "Stephen Moses"
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'''Stephen Moses''', Professor, Departments of Medical Microbiology, Community Health Sciences and Medicine. Stephen Moses has been a circumcision proponent since at least 1994.<ref name="Moses1994">{{REFjournal | '''Stephen Moses''', Professor, Departments of Medical Microbiology, Community Health Sciences and Medicine. Stephen Moses has been a circumcision proponent since at least 1994.<ref name="Moses1994">{{REFjournal | ||
|last=Moses | |last=Moses | ||
| − | | | + | |init=S |
| − | | | + | |author-link=Stephen Moses |
| − | | | + | |last2=Plummer |
| − | | | + | |init2=FA |
| − | | | + | |last3=Bradley |
| − | | | + | |init3=JE |
| − | | | + | |last4=Ndinya-Achola |
| − | | | + | |init4=JO |
| − | | | + | |last5=Nagelkerke |
| − | | | + | |init5=NJ |
| − | | | + | |last6=Ronald |
| + | |init6=AR | ||
|title=The association between lack of male circumcision and risk for HIV infection: a review of the epidemiological data | |title=The association between lack of male circumcision and risk for HIV infection: a review of the epidemiological data | ||
|journal=Sex Transm Dis | |journal=Sex Transm Dis | ||
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}}</ref> Moses (along with [[Robert C. Bailey]]) was responsible for one of the three major African circumcision trials (funded by NIAID and the Canadian Institutes of Health Research)<ref>{{REFjournal | }}</ref> Moses (along with [[Robert C. Bailey]]) was responsible for one of the three major African circumcision trials (funded by NIAID and the Canadian Institutes of Health Research)<ref>{{REFjournal | ||
|last=Krieger | |last=Krieger | ||
| − | | | + | |init=JN |
|last2=Bailey | |last2=Bailey | ||
| − | | | + | |init2=RC |
|last3=Opeya | |last3=Opeya | ||
| − | | | + | |init3=J |
|etal=yes | |etal=yes | ||
|date=2005-11 | |date=2005-11 | ||
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|DOI=10.1111/j.1464-410X.2005.05810.x | |DOI=10.1111/j.1464-410X.2005.05810.x | ||
|accessdate= | |accessdate= | ||
| − | }}</ref> which are being used by the [[World Health Organization]] (under the guide of [[UNAIDS]]) to endorse circumcision as an HIV prevention method.<ref>{{REFweb | + | }}</ref> which are being used by the [[World Health Organization]] (under the guide of [[UNAIDS]]) to endorse circumcision as an [[HIV]] prevention method.<ref>{{REFweb |
|last=World Health Organization | |last=World Health Organization | ||
|first= | |first= | ||
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== Interests == | == Interests == | ||
| − | According to Stephen's bio, his interest is in biological and behavioural risk factors for STI/HIV transmission.<ref name='moses-bio'>{{REFweb | + | According to Stephen's bio, his interest is in biological and behavioural risk factors for STI/[[HIV]] transmission.<ref name='moses-bio'>{{REFweb |
| − | |last= | + | |last=Moses |
|first=Stephen | |first=Stephen | ||
| − | |title= | + | |title=Dr. Stephen Moses |
|url=http://umanitoba.ca/faculties/medicine/units/medical_microbiology/faculty/StephenMoses.html | |url=http://umanitoba.ca/faculties/medicine/units/medical_microbiology/faculty/StephenMoses.html | ||
| − | |publisher=University of Manitoba | + | |publisher={{UNI|University of Manitoba|UManitoba}} |
|date= | |date= | ||
|accessdate=2011-02-23 | |accessdate=2011-02-23 | ||
| Line 75: | Line 76: | ||
== RCT in Kenya == | == RCT in Kenya == | ||
| − | + | Three trials were funded by the American [[National Institutes of Health]].<ref name='DOC 2008'>{{REFweb | |
|quote=...funding from the United States National Institutes of Health to conduct randomized controlled trials ({{#tip-text:RCT|Randomized controlled trial}}s) in Africa. | |quote=...funding from the United States National Institutes of Health to conduct randomized controlled trials ({{#tip-text:RCT|Randomized controlled trial}}s) in Africa. | ||
|last= | |last= | ||
|first= | |first= | ||
| − | |publisher=Doctors Opposing Circumcision | + | |publisher=[[Doctors Opposing Circumcision (D.O.C.)]] |
| − | |date= | + | |date=2016 |
| − | |title= | + | |title=HIV/AIDS |
| − | |url= | + | |url=https://www.doctorsopposingcircumcision.org/for-professionals/alleged-medical-benefits/hivaids/ |
| − | |accessdate= | + | |accessdate=2020-03-23 |
| + | }}</ref>Of the three {{#tip-text:RCT|Randomized controlled trial}}s being used by the [[WHO]] to endorse circumcision as [[HIV]] prevention, Stephen Moses and [[Robert C. Bailey]] headed the {{#tip-text:RCT|Randomized controlled trial}} that was carried out in Kenya.<ref>{{RCT Bailey et al 2007}}</ref> Moses obviously brought his pre-existing bias in favor of male circumcision into the trial, so he did not start from a neutral position. | ||
| + | |||
| + | Moses' research on circumcision protection from [[HIV]] infection is now completely discredited. Boyle & Hill (2011) reviewed the three randomized controlled trials (RCTs) and found disabling methodological and statistical errors in all three. Although a 60 percent ''relative'' reduction in [[HIV]] was claimed, the ''absolute'' reduction was a statistically insignificant 1.3 percent.<ref name="boyle-hill2011">{{BoyleGJ HillG 2011}}</ref> [[Michel Garenne|Garenne]] & Matthews (2019) report that circumcised men have as much [[HIV]] infection as intact men.<ref>{{REFjournal | ||
| + | |last=Garenne | ||
| + | |init=M | ||
| + | |author-link=Michel Garenne | ||
| + | |last2=Matthews | ||
| + | |init2=A | ||
| + | |author2-link= | ||
| + | |etal=no | ||
| + | |title=Voluntary medical male circumcision and HIV in Zambia: expectations and observations | ||
| + | |trans-title= | ||
| + | |language= | ||
| + | |journal=J Biosoc Science | ||
| + | |location= | ||
| + | |date=2019-10-01 | ||
| + | |volume=14 | ||
| + | |issue= | ||
| + | |pages=1-13 | ||
| + | |url= | ||
| + | |quote= | ||
| + | |pubmedID=31608845 | ||
| + | |pubmedCID= | ||
| + | |DOI=10.1017/S0021932019000634 | ||
| + | |accessdate=2020-03-25 | ||
}}</ref> | }}</ref> | ||
== Active projects == | == Active projects == | ||
| − | * A randomized, controlled trial of male circumcision to reduce HIV incidence in Kisumu, Kenya.<ref name='moses-bio'/><br><small>[[National Institutes of Health]].</small> | + | * A randomized, controlled trial of male circumcision to reduce [[HIV]] incidence in Kisumu, Kenya.<ref name='moses-bio'/><br><small>[[National Institutes of Health]].</small> |
| − | * Scaling up HIV prevention in Karnataka and southern Maharashtra, Phase II.<ref name='moses-bio'/><br><small>[[Bill & Melinda Gates Foundation]].</small> | + | * Scaling up [[HIV]] prevention in Karnataka and southern Maharashtra, Phase II.<ref name='moses-bio'/><br><small>[[Bill & Melinda Gates Foundation]].</small> |
| − | * Monitoring and evaluation of the Avahan project in India.<ref name='moses-bio'/><br><small>[[Bill & Melinda Gates Foundation]].</small> | + | * Monitoring and evaluation of the Avahan project in [[India]].<ref name='moses-bio'/><br><small>[[Bill & Melinda Gates Foundation]].</small> |
| − | * Technical assistance to improve maternal, neonatal & child health through National Rural Health Mission, India.<ref name='moses-bio'/><br><small>[[Bill & Melinda Gates Foundation]].</small> | + | * Technical assistance to improve maternal, neonatal & child health through National Rural Health Mission, [[India]].<ref name='moses-bio'/><br><small>[[Bill & Melinda Gates Foundation]].</small> |
| − | * Mapping key populations for HIV prevention in Sri Lanka.<ref name='moses-bio'/><br><small>World Bank.</small> | + | * Mapping key populations for [[HIV]] prevention in Sri Lanka.<ref name='moses-bio'/><br><small>World Bank.</small> |
| − | + | {{PUB}} | |
| − | * | + | * {{REFjournal |
|last=Smith | |last=Smith | ||
| − | | | + | |init=JS |
|last2=Backes | |last2=Backes | ||
| − | | | + | |init2=DM |
|last3=Hudgens | |last3=Hudgens | ||
| − | | | + | |init3=MG |
| + | |last4=Bailey | ||
| + | |first4=Robert C. | ||
| + | |init4=RC | ||
| + | |author4-link=Robert C. Bailey | ||
| + | |last5=Agot | ||
| + | |init5=K | ||
| + | |last6=Ndinya-Achola | ||
| + | |init6=JO | ||
| + | |last7=Moses | ||
| + | |init7=S | ||
| + | |author7-link=Stephen Moses | ||
|etal=yes | |etal=yes | ||
|date=2010-01 | |date=2010-01 | ||
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|DOI=10.1002/ijc.24770 | |DOI=10.1002/ijc.24770 | ||
|accessdate= | |accessdate= | ||
| − | }} | + | }} |
| − | * | + | * {{REFjournal |
|last=Moses | |last=Moses | ||
| − | | | + | |init=S |
| + | |author-link=Stephen Moses | ||
|date=2009-10 | |date=2009-10 | ||
| − | |title=Male circumcision: a new approach to reducing HIV transmission | + | |title=Top Achievements in Health Research: Male circumcision: a new approach to reducing HIV transmission |
| − | |journal=CMAJ | + | |journal=CIHR/CMAJ |
|volume=181 | |volume=181 | ||
|issue=8 | |issue=8 | ||
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|DOI=10.1503/cmaj.090809 | |DOI=10.1503/cmaj.090809 | ||
|accessdate= | |accessdate= | ||
| − | }} | + | }} |
| − | * | + | * {{REFjournal |
|last=Mehta | |last=Mehta | ||
| − | | | + | |init=SD |
|last2=Gray | |last2=Gray | ||
| − | | | + | |init2=RH |
| + | |author2-link=Ronald H. Gray | ||
|last3=Auvert | |last3=Auvert | ||
| − | | | + | |init3=B |
| + | |author3-link=Bertran Auvert | ||
| + | |last4=Moses | ||
| + | |init4=S | ||
| + | |author4-link=Stephen Moses | ||
| + | |last5=Kigozi | ||
| + | |init5=G | ||
| + | |author5-link=Godfrey Kigozi | ||
| + | |last6=Taljaard | ||
| + | |init6=D | ||
| + | |last7=Puren | ||
| + | |init7=A | ||
| + | |last8=Agot | ||
| + | |init8=K | ||
| + | |last9=Serwadda | ||
| + | |init9=D | ||
| + | |other=Parker CB, [[Maria Wawer|Wawer MJ]], [[Robert C. Bailey|Bailey RC]] | ||
|etal=yes | |etal=yes | ||
|date=2007-07 | |date=2007-07 | ||
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|accessdate= | |accessdate= | ||
}} | }} | ||
| − | + | * {{RCT Bailey et al 2007}} | |
| − | * | + | * {{REFjournal |
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|last=Nagelkerke | |last=Nagelkerke | ||
| − | | | + | |init=NJD |
|last2=Moses | |last2=Moses | ||
| − | | | + | |init2=S |
| + | |author2-link=Stephen Moses | ||
|last3=de Vlas | |last3=de Vlas | ||
| − | | | + | |init3=SJ |
|last4=Bailey | |last4=Bailey | ||
| − | | | + | |init4=RC |
| + | |author4-link=Robert C. Bailey | ||
|date=2007 | |date=2007 | ||
|title=Modelling the public health impact of male circumcision for HIV prevention in high prevalence areas in Africa | |title=Modelling the public health impact of male circumcision for HIV prevention in high prevalence areas in Africa | ||
| Line 190: | Line 227: | ||
|DOI=10.1186/1471-2334-7-16 | |DOI=10.1186/1471-2334-7-16 | ||
|accessdate= | |accessdate= | ||
| − | }} | + | }} |
| − | * | + | * {{REFjournal |
|last=Krieger | |last=Krieger | ||
| − | | | + | |init=JN |
|last2=Bailey | |last2=Bailey | ||
| − | | | + | |init2=RC |
| − | |last3= | + | |author2-link=Robert C. Bailey |
| − | | | + | |last3=Agot |
| + | |init3=K | ||
| + | |last4=Parker | ||
| + | |init4=C | ||
| + | |last5=Ndinya-Achola | ||
| + | |init5=JO | ||
| + | |last6=Moses | ||
| + | |init6=S | ||
| + | |author6-link=Stephen Moses | ||
|etal=yes | |etal=yes | ||
|date=2007 | |date=2007 | ||
|title=Adult male circumcision outcomes: experience in a developing country setting | |title=Adult male circumcision outcomes: experience in a developing country setting | ||
| − | |journal=Urol | + | |journal=Urol Int |
|volume=78 | |volume=78 | ||
|issue=3 | |issue=3 | ||
| Line 210: | Line 255: | ||
|accessdate= | |accessdate= | ||
}} | }} | ||
| − | |||
{{SEEALSO}} | {{SEEALSO}} | ||
| − | |||
* [[Bias]] | * [[Bias]] | ||
| + | * [[Canada]] | ||
* [[Circumcised doctors]] | * [[Circumcised doctors]] | ||
| Line 221: | Line 265: | ||
{{DEFAULTSORT:Moses, Stephen}} | {{DEFAULTSORT:Moses, Stephen}} | ||
| − | [[Category: | + | [[Category:Person]] |
| + | [[Category:Male]] | ||
| + | |||
[[Category:Researcher]] | [[Category:Researcher]] | ||
| + | [[Category:Author]] | ||
| + | |||
| + | [[Category:Canada]] | ||
[[Category:Circumcision in Africa]] | [[Category:Circumcision in Africa]] | ||
| − | + | ||
[[Category:From CircLeaks]] | [[Category:From CircLeaks]] | ||
[[Category:From IntactWiki]] | [[Category:From IntactWiki]] | ||
[[de:{{FULLPAGENAME}}]] | [[de:{{FULLPAGENAME}}]] | ||
Latest revision as of 14:57, 8 July 2024
Stephen Moses, Professor, Departments of Medical Microbiology, Community Health Sciences and Medicine. Stephen Moses has been a circumcision proponent since at least 1994.[1] Moses (along with Robert C. Bailey) was responsible for one of the three major African circumcision trials (funded by NIAID and the Canadian Institutes of Health Research)[2] which are being used by the World Health Organization (under the guide of UNAIDS) to endorse circumcision as an HIV prevention method.[3]
|
| Stephen Moses |
| Associates With: |
| Gilgal Society Circlist |
| Colleagues & Benefactors: |
| Daniel T. Halperin Edgar J. Schoen Robert C. Bailey Bertran Auvert Maria J. Wawer Brian J. Morris |
Contents
Interests
According to Stephen's bio, his interest is in biological and behavioural risk factors for STI/HIV transmission.[4] Moses has been an advocate of circumcision since at least 1994.[1]
RCT in Kenya
Three trials were funded by the American National Institutes of Health.[5]Of the three RCTs being used by the WHO to endorse circumcision as HIV prevention, Stephen Moses and Robert C. Bailey headed the RCT that was carried out in Kenya.[6] Moses obviously brought his pre-existing bias in favor of male circumcision into the trial, so he did not start from a neutral position.
Moses' research on circumcision protection from HIV infection is now completely discredited. Boyle & Hill (2011) reviewed the three randomized controlled trials (RCTs) and found disabling methodological and statistical errors in all three. Although a 60 percent relative reduction in HIV was claimed, the absolute reduction was a statistically insignificant 1.3 percent.[7] Garenne & Matthews (2019) report that circumcised men have as much HIV infection as intact men.[8]
Active projects
- A randomized, controlled trial of male circumcision to reduce HIV incidence in Kisumu, Kenya.[4]
National Institutes of Health. - Scaling up HIV prevention in Karnataka and southern Maharashtra, Phase II.[4]
Bill & Melinda Gates Foundation. - Monitoring and evaluation of the Avahan project in India.[4]
Bill & Melinda Gates Foundation. - Technical assistance to improve maternal, neonatal & child health through National Rural Health Mission, India.[4]
Bill & Melinda Gates Foundation. - Mapping key populations for HIV prevention in Sri Lanka.[4]
World Bank.
Publications
Smith JS, Backes DM, Hudgens MG, Bailey RC, Agot K, Ndinya-Achola JO, Moses S, et al. Prevalence and risk factors of human papillomavirus infection by penile site in uncircumcised Kenyan men. Int. J. Cancer. January 2010; 126(2): 572–7. PMID. PMC. DOI.- Moses S. Top Achievements in Health Research: Male circumcision: a new approach to reducing HIV transmission. CIHR/CMAJ. October 2009; 181(8): E134–5. PMID. PMC. DOI.
- Mehta SD, Gray RH, Auvert B, Moses S, Kigozi G, Taljaard D, Puren A, Agot K, Serwadda D, et al. Does sex in the early period after circumcision increase HIV-seroconversion risk? Pooled analysis of adult male circumcision clinical trials. AIDS. July 2007; 23(12): 1557–64. PMID. PMC. DOI.
- Bailey RC, Moses S, Parker CB, et al. Male circumcision for HIV prevention in young men in Kisumu, Kenya: A randomised controlled trial. Lancet. 24 February 2007; 369(9562): 643–56. PMID. DOI. Retrieved 31 December 2021.
- Nagelkerke NJD, Moses S, de Vlas SJ, Bailey RC. Modelling the public health impact of male circumcision for HIV prevention in high prevalence areas in Africa. BMC Infect. Dis.. 2007; 7: 16. PMID. PMC. DOI.
- Krieger JN, Bailey RC, Agot K, Parker C, Ndinya-Achola JO, Moses S, et al. Adult male circumcision outcomes: experience in a developing country setting. Urol Int. 2007; 78(3): 235–40. PMID. DOI.
See also
References
- ↑ a b Moses S, Plummer FA, Bradley JE, Ndinya-Achola JO, Nagelkerke NJ, Ronald AR. The association between lack of male circumcision and risk for HIV infection: a review of the epidemiological data. Sex Transm Dis. 1994; 21: 201-210.
- ↑ Krieger JN, Bailey RC, Opeya J, et al. Adult male circumcision: results of a standardized procedure in Kisumu District, Kenya. BJU Int.. November 2005; 96(7): 1109–13. PMID. DOI.
- ↑
World Health Organization (27 March 2007). WHO and UNAIDS announce recommendations from expert consultation on male circumcision for HIV prevention
. Retrieved 23 February 2011. - ↑ a b c d e f Moses, Stephen.
Dr. Stephen Moses
, University of Manitoba. Retrieved 23 February 2011. - ↑ (2016).
HIV/AIDS
, Doctors Opposing Circumcision (D.O.C.). Retrieved 23 March 2020.
Quote:...funding from the United States National Institutes of Health to conduct randomized controlled trials (RCTs) in Africa.
- ↑ Bailey RC, Moses S, Parker CB, et al. Male circumcision for HIV prevention in young men in Kisumu, Kenya: A randomised controlled trial. Lancet. 24 February 2007; 369(9562): 643–56. PMID. DOI. Retrieved 31 December 2021.
- ↑ Boyle GJ, Hill G. Sub-Saharan African randomised clinical trials into male circumcision and HIV transmission: Methodological, ethical and legal concerns
. Thompson Reuter. December 2011; 19(2): 316-34. PMID. Retrieved 30 December 2020.
- ↑ Garenne M, Matthews A. Voluntary medical male circumcision and HIV in Zambia: expectations and observations. J Biosoc Science. 1 October 2019; 14: 1-13. PMID. DOI. Retrieved 25 March 2020.
