Preputial sac: Difference between revisions

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  |accessdate=2022-10-07
  |accessdate=2022-10-07
}}</ref> The preputial sac may also be called the '''sub-preputial space''' or '''preputial cavity'''.
}}</ref> The preputial sac may also be called the '''sub-preputial space''' or '''preputial cavity'''.
==Description==


The preputial sac is lined with [[mucosa]] as is appropriate for an internal organ.<ref name="cold-taylor1999">{{ColdCJ TaylorJR 1999}}</ref>  
The preputial sac is lined with [[mucosa]] as is appropriate for an internal organ.<ref name="cold-taylor1999">{{ColdCJ TaylorJR 1999}}</ref>  
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}}</ref> Moistness also may be maintained by [[transudation]].<ref name="cold-taylor1999" />
}}</ref> Moistness also may be maintained by [[transudation]].<ref name="cold-taylor1999" />


Lakshmanan & Parkash (1980) described the muscle fibers in the prepuce (known as the [[dartos]]), which contract to keep the prepuce snugly close to the glans penis. The muscle fibers form a whorl at the tip to keep the tip of the [[foreskin]] and keep the preputial sac closed against the outside world and contamination.<ref>{{REFjournal
Lakshmanan & Parkash (1980) described the muscle fibers in the [[prepuce]] (known as the [[dartos]]), which contract to keep the prepuce snugly close to the [[glans penis]]. The muscle fibers form a whorl at the tip to keep the tip of the [[foreskin]] and keep the preputial sac closed against the outside world and contamination.<ref>{{REFjournal
  |last=Lakshmanan
  |last=Lakshmanan
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Cold & Taylor (1999) described a healthy microbiome that lives within the preputial sac.<ref name="cold-taylor1999" /> They also reported that Langerhans cells are found in the mucosa of the preputial sac. [[Langerhans cells]] are part of the immunological defenses of the penis. De Witte et al. (2007) reported that Langerhans cells produce a substance named ''langerin''. The langerin offers protection against HIV infection:
Cold & Taylor (1999) described a healthy microbiome that lives within the preputial sac.<ref name="cold-taylor1999" /> They also reported that Langerhans cells are found in the mucosa of the preputial sac. [[Langerhans cells]] are part of the immunological defenses of the [[penis]]. De Witte et al. (2007) reported that Langerhans cells produce a substance named ''langerin''. The langerin offers protection against HIV infection:


{{Citation
{{Citation
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  |ref=<ref>{{DeWitte etal 2007}}</ref>
  |ref=<ref>{{DeWitte etal 2007}}</ref>
}}
}}
 
==Washing==
Birley et al. (1993) studied 43 men with recurrent or persistent [[balanitis]] at an outpatient genitourinary disease clinic in London, [[United Kingdom| UK]] where most men are [[intact]]. Of the study group only 33 percent were [[circumcised]]. Birley and colleagues discovered that the men in that group washed frequently with soap or shower gel.  
Birley et al. (1993) studied 43 men with recurrent or persistent [[balanitis]] at an outpatient genitourinary disease clinic in London, [[United Kingdom| UK]] where most men are [[intact]]. Of the study group only 33 percent were [[circumcised]]. Birley and colleagues discovered that the men in that group washed frequently with soap or shower gel.